Results 71 to 80 of about 2,317,928 (319)
Efficient Method for Molecular Characterization of the 5′ and 3′ Ends of the Dengue Virus Genome
Dengue is a mosquito-borne disease that is of major importance in public health. Although it has been extensively studied at the molecular level, sequencing of the 5′ and 3′ ends of the untranslated regions (UTR) commonly requires specific approaches for
Alicia Rosales-Munar +4 more
doaj +1 more source
Assessing Incrementality in Sequence-to-Sequence Models [PDF]
Since their inception, encoder-decoder models have successfully been applied to a wide array of problems in computational linguistics. The most recent successes are predominantly due to the use of different variations of attention mechanisms, but their cognitive plausibility is questionable.
Ulmer, D., Hupkes, D., Bruni, E.
openaire +3 more sources
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider +15 more
wiley +1 more source
Species identification and profiling of complex microbial communities using shotgun Illumina sequencing of 16S rRNA amplicon sequences. [PDF]
The high throughput and cost-effectiveness afforded by short-read sequencing technologies, in principle, enable researchers to perform 16S rRNA profiling of complex microbial communities at unprecedented depth and resolution. Existing Illumina sequencing
Niranjan Nagarajan +23 more
core +1 more source
ABSTRACT Background Childhood aplastic anemia (AA) is a rare disease, and both the disease itself and its treatment cause significant morbidity. We aimed to determine the contemporary incidence of childhood AA in Finland, to compare the clinical characteristics of AA against inherited bone marrow failure syndromes (IBMFS) and refractory cytopenia of ...
Lauri‐Matti Kulmala +8 more
wiley +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
ParMap, an Algorithm for the Identification of Complex Genomic Variations in Nextgen Sequencing Data [PDF]
Next-generation sequencing produces high-throughput data, albeit with greater error and shorter reads than traditional Sanger sequencing methods. This complicates the detection of genomic variations, especially, small insertions and deletions.
Raul Rabadan +4 more
core +1 more source
estMOI: estimating multiplicity of infection using parasite deep sequencing data. [PDF]
Individuals living in endemic areas generally harbour multiple parasite strains. Multiplicity of infection (MOI) can be an indicator of immune status and transmission intensity.
Sutherland, Colin J +5 more
core +1 more source
K-mer analysis of long-read alignment pileups for structural variant genotyping
Accurately genotyping structural variant (SV) alleles is crucial to genomics research. We present a novel method (kanpig) for genotyping SVs that leverages variant graphs and k-mer vectors to rapidly generate accurate SV genotypes.
Adam C. English +4 more
doaj +1 more source
Modeling Confidence in Sequence-to-Sequence Models [PDF]
Recently, significant improvements have been achieved in various natural language processing tasks using neural sequence-to-sequence models. While aiming for the best generation quality is important, ultimately it is also necessary to develop models that can assess the quality of their output.
Niehues, J., Pham, N.-Q.
openaire +3 more sources

