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Mathematics, 2022 Given an n-element point set in the plane, in how many ways can it be peeled off until no point remains? Only one extreme point can be removed at a time. The answer obviously depends on the point set. If the points are in convex position, there are exactly n! ways, which is the maximum number of ways for n points. But what is the minimum number?
Adrian Dumitrescu, Géza Tóth
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Sequencing technologies and genome sequencing [PDF]
Journal of Applied Genetics, 2011 The high-throughput - next generation sequencing (HT-NGS) technologies are currently the hottest topic in the field of human and animals genomics researches, which can produce over 100 times more data compared to the most sophisticated capillary sequencers based on the Sanger method.
Pareek, Chandra Shekhar +2 more
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Recognizing Sequences of Sequences
PLoS Computational Biology, 2009 The brain's decoding of fast sensory streams is currently impossible to emulate, even approximately, with artificial agents. For example, robust speech recognition is relatively easy for humans but exceptionally difficult for artificial speech recognition systems.
Kiebel, S J +3 more
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Tournament Sequences and Meeussen Sequences [PDF]
The Electronic Journal of Combinatorics, 2000 A tournament sequence is an increasing sequence of positive integers $(t_1,t_2,\ldots)$ such that $t_1=1$ and $t_{i+1} \leq 2t_i$. A Meeussen sequence is an increasing sequence of positive integers $(m_1,m_2,\ldots)$ such that $m_1=1$, every nonnegative integer is the sum of a subset of the $\{m_i\}$, and each integer $m_i-1$ is the sum of a unique ...
Cook, Matthew, Kleber, Michael
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Legislative and Administrative Processes. By Hans A. Linde and George Bunn; Introduction to the American Public Law System: Cases and Materials. By Jerry L. Mashaw and Richard A. Merrill [PDF]
, 1977 Background: Genome and transcriptome sequencing applications that rely on variation in sequence depth can be negatively affected if there are systematic biases in coverage.
Ekblom, Robert +2 more
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Genomic variant benchmark: if you cannot measure it, you cannot improve it
Genome Biology, 2023 Genomic benchmark datasets are essential to driving the field of genomics and bioinformatics. They provide a snapshot of the performances of sequencing technologies and analytical methods and highlight future challenges.
Sina Majidian +4 more
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An Ultrahigh-throughput Microfluidic Platform for Single-cell Genome Sequencing. [PDF]
, 2018 Sequencing technologies have undergone a paradigm shift from bulk to single-cell resolution in response to an evolving understanding of the role of cellular heterogeneity in biological systems.
Abate, Adam R +3 more
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Deep convolutional neural networks for accurate somatic mutation detection
Nature Communications, 2019 Somatic mutations are crucial to the understanding of cancer genesis, progression, and treatment, but are still challenging to detect. Here the authors present NeuSomatic, a convolutional neural network approach for accurate somatic mutation detection ...
Sayed Mohammad Ebrahim Sahraeian +5 more
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BMC Genomics, 2017 Background Characterization of genomic structural variation (SV) is essential to expanding the research and clinical applications of genome sequencing.
Oliver A. Hampton +10 more
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BMC Cancer, 2020 Background Identifying and tracking somatic mutations in cell-free DNA (cfDNA) by next-generation sequencing (NGS) has the potential to transform the clinical management of subjects with advanced non-small cell lung cancer (NSCLC). Methods Baseline tumor
John Jiang +14 more
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