Results 31 to 40 of about 3,312,497 (352)
SVhound: detection of regions that harbor yet undetected structural variation
BMC Bioinformatics, 2023 Background Recent population studies are ever growing in number of samples to investigate the diversity of a population or species. These studies reveal new polymorphism that lead to important insights into the mechanisms of evolution, but are also ...
Luis F. Paulin +5 more
doaj +1 more source
Frontiers in Molecular Biosciences, 2022 Background and Objective: One of the most recent forms of programmed cell death, ferroptosis, is crucial in tumorigenesis. Ferroptosis is characterized by iron-dependent oxidative destruction of cellular membranes following the antioxidant system’s ...
Salem Baldi +11 more
doaj +1 more source
High-throughput Quant-iT PicoGreen assay using an automated liquid handling system
BioTechniques, 2019 Workflows in NGS facilities require high-standard practices and high-throughput pipelines to process the large number of samples received in a timely manner. Downstream protocols such as NGS library preparation require accurate estimation of nucleic acid
Kay Anantanawat +3 more
doaj +1 more source
Journal of Molecular Pathology, 2021 Given the increase in genomic testing in routine clinical use, there is a growing need for digital technology solutions to assist pathologists, oncologists, and researchers in translating variant calls into actionable knowledge to personalize patient ...
Stephanie J. Yaung, Adeline Pek
doaj +1 more source
Comparison of SARS-CoV-2 sequencing using the ONT GridION and the Illumina MiSeq
BMC Genomics, 2022 Background Over 4 million SARS-CoV-2 genomes have been sequenced globally in the past 2 years. This has been crucial in elucidating transmission chains within communities, the development of new diagnostic methods, vaccines, and antivirals.
Derek Tshiabuila +12 more
doaj +1 more source
Pyrosequencing/Sanger Plant Genome Assembly (Limitations, Problems And Solutions) - On The Way To Cucumber (Cucumis sativus L. cv. Borszczagowski) Draft Genome Sequence Publishing [PDF]
, 2010 Genome sequencing give us an opportunity to broaden the range and improve the quality of omics studies. New sequencing technologies make it possible to achieve the sequencing reads fast and cheap.
Rafal Woycicki, Zbigniew Przybecki
core +2 more sources
Microbial Biotechnology, 2021 Summary Phi29 DNA polymerase (Phi29 Pol) has been successfully applied in DNA nanoball‐based sequencing, real‐time DNA sequencing from single polymerase molecules and nanopore sequencing employing the sequencing by synthesis (SBS) method.
Yaping Gao +6 more
doaj +1 more source
16S rRNA gene sequencing of mock microbial populations- impact of DNA extraction method, primer choice and sequencing platform [PDF]
, 2016 peer-reviewedBackground Next-generation sequencing platforms have revolutionised our ability to investigate the microbiota composition of complex environments, frequently through 16S rRNA gene sequencing of the bacterial component of the
Claesson, Marcus J. +4 more
core +2 more sources
BMC Genomics, 2020 Background Orang-utans comprise three critically endangered species endemic to the islands of Borneo and Sumatra. Though whole-genome sequencing has recently accelerated our understanding of their evolutionary history, the costs of implementing routine ...
Graham L. Banes +8 more
doaj +1 more source
International Journal of Microbiology, 2022 Background. Antimicrobial resistance is limiting treatment options for Neisseria gonorrhoeae infections. To aid or replace culture and the syndromic management approach, molecular assays are required for antimicrobial susceptibility testing to guide ...
Nireshni Mitchev +10 more
doaj +1 more source