Results 91 to 100 of about 154,271 (296)

Sequential decision problems, dependently typed solutions

open access: yes, 2013
We propose a dependently typed formalization for a simple class of sequential decision problems. For this class of problems, we im- plement a generic version of Bellman's backwards induction algorithm [2] and a machine checkable proof that the proposed ...
Botta, Nicola   +2 more
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Parsing a perceptual decision into a sequence of moments of thought

open access: yesFrontiers in Integrative Neuroscience, 2011
Theoretical, computational and experimental studies have converged to a model of decision-making in which sensory evidence is stochastically integrated to a threshold, implementing a shift from an analog to a discrete form of computation.
Martin eGraziano   +3 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Adequate Moods for Non-EU Decision Making in a Sequential Framework [PDF]

open access: yes
In a dynamic (sequential) framework, departures from the independence axiom (IND) are reputed to induce violations of dynamic consistency (DC), which may in turn have undesirable normative consequences.
Nathalie Etchart(-Vincent)
core  

The Effect of Behavioral Synchrony on Choosing Compensation in Adolescents and Adults’ Decision-Making [PDF]

open access: yesپژوهش‌های کاربردی روانشناختی
The objective of this study was to investigate the impact of behavioral synchrony on compensation in sequential decision-making among individuals aged 15 to 25.
Fatemeh Ebrahimi   +2 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

The Sequencing Problem in Sequential Investigation Processes [PDF]

open access: yes
Many decision problems in various fields of application can be characterized as diagnostic problems trying to assess the true state (of the world) of given cases.
Jürgen-Peter Kretschmer
core  

Failing Despite Knowing. Repeated Decision-Making During Binary Random Sequences with Asymmetric Probabilities

open access: yesOpen Psychology
Previous research shows that people often misinterpret randomness, expecting short-term outcomes to balance out, known as negative recency. Most studies have focused on binary events with equal odds (1:1).
Uatkán Ajna   +2 more
doaj   +1 more source

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