Results 131 to 140 of about 10,678 (163)

Glioblastoma stem cells resist cuproptosis with circadian variation of copper levels. [PDF]

J Clin Invest
Yuan F, Wu X, Yuan H, Wang D, Huang T, Zhang P, Mi H, Wu W, Taori S, Chan P, Miki K, Ghoche MT, Zhao L, Abdullah KG, Kay SA, Wu Q, Rich JN.   +16 more
europepmc   +1 more source

Mitochondrial autophagy inhibits nucleotide-binding oligomerization domain-like receptor protein 3-mediated pyroptosis and alleviates endothelial cell injury in pregnancy-induced hypertension. [PDF]

Cytojournal
Zhang M, Zhang X, Mao L.
europepmc   +1 more source

A special issue of Essays in Biochemistry on proteasome and protein degradation. [PDF]

Essays Biochem
Sahu I, Glickman MH.
europepmc   +1 more source

SQSTM1/p62 at the Crossroads of Autophagy, Inflammation, and Lethal Infection. [PDF]

Cells
Zhang R, Kang R, Tang D.
europepmc   +1 more source

Early Taurine Administration Decreases the Levels of Receptor-Interacting Serine/Threonine Protein Kinase 1 in the Duchenne Mouse Model <i>mdx</i>. [PDF]

Brain Sci
Dias M, Dhuyvetter H, Byttebier E, Merckx C, De Bleecker JL, De Paepe B.   +5 more
europepmc   +1 more source

p62-dependent caspase-2 activation governs TDP-43 clearance and neuronal fate in ALS. [PDF]

Cell Death Dis
Volik PI, Kopeina GS, Zhivotovsky B, Zamaraev AV.   +3 more
europepmc   +1 more source

Sequestosome 1 (SQSTM1/p62) maintains protein folding capacity under endoplasmic reticulum stress in mouse hypothalamic organotypic culture

Sequestosome 1 (SQSTM1/p62) maintains protein folding capacity under endoplasmic reticulum stress in mouse hypothalamic organotypic culture
openaire  

The sequestosome 1 protein: therapeutic vulnerabilities in ovarian cancer

Clinical and Translational Oncology, 2023
Ovarian cancer (OC) is the most deadly tumor that may develop in a woman's reproductive system. It is also one of the most common causes of death among those who have been diagnosed with cancer in women. An adapter protein known as sequestosome 1(SQSTM1) or p62 is primarily responsible for the transportation, degradation, and destruction of a wide ...
Seyedeh Mojgan Ghalandarpoor-Attar, Maryam Rabiei   +1 more
exaly   +4 more sources

Sequestosome 1/p62: a multi-domain protein with multi-faceted functions

Frontiers in Biology, 2012
The Sequestosome 1/p62 protein has been implicated in the regulation of a multitude of cellular processes such as NF-κB signaling, NRF2-driven oxidative stress response, protein turnover through the ubiquitin-proteasome pathway and the autophagosome/lysosome pathway, apoptosis and cellular metabolism.
József Gal, Haining Zhu, Zhu Haining
exaly   +4 more sources

Inhibition of sequestosome 1/p62 up-regulation prevents aggregation of ubiquitinated proteins induced by prostaglandin J2 without reducing its neurotoxicity

Molecular and Cellular Neurosciences, 2005
The mechanisms implicated in the aggregation of ubiquitinated proteins detected in neurodegenerative disorders remain elusive. We report that prostaglandin J2 (PGJ2), an endogenous product of inflammation, up-regulates sequestosome 1/p62 in a time- and dose-dependent manner in human neuroblastoma SK-N-SH cells.
Maria E Figueiredo-Pereira
exaly   +4 more sources