Results 161 to 170 of about 470,172 (244)

A Python package based on robust statistical analysis for serial crystallography data processing. [PDF]

Acta Crystallogr D Struct Biol, 2023
Hadian-Jazi M, Sadri A.
europepmc   +1 more source

Site‐Selective Ligand Selection by Mutational Profiling for Covalent RNA Targeting

Angewandte Chemie, EarlyView.
Using a mutational profiling approach an RNA‐targeted covalent probe was developed that is highly selective for the FMN riboswitch. The covalency was further supported by mass spectrometry experiments. The covalent probe selectively modifies the riboswitch at low micromolar concentrations within 10 min and remains functional when applied to an entire ...
Phillip Yesley, Georgia Poulladofonou, Danny Incarnato, Willem A. Velema   +3 more
wiley   +1 more source

Testing the limits: serial crystallography using unpatterned fixed targets. [PDF]

IUCrJ
Gorel A, Shoeman RL, Hartmann E, Nizinski S, Appleby MV, Beale EV, Dworkowski F, Gotthard GC, Beale JH, Holton J, Doak RB, Barends TRM, Schlichting I.   +12 more
europepmc   +1 more source

Correction of rhodopsin serial crystallography diffraction intensities for a lattice-translocation defect. [PDF]

Acta Crystallogr D Struct Biol, 2023
Rodrigues MJ, Casadei CM, Weinert T, Panneels V, Schertler GFX.   +4 more
europepmc   +1 more source

Diffractive imaging and serial crystallography [PDF]

Acta Crystallographica Section A Foundations of Crystallography, 2008
U.J. Weierstall, J.C.H. Spence, D. Starodub, K. Schmidt, R.B. Doak, D. Shapiro, H. Chapman, S. Marchesini   +7 more
openaire   +1 more source

Real-time capture of domain movements during copper amine oxidase catalysis by mix-and-inject serial crystallography. [PDF]

Nat Commun
Murakawa T, Suzuki M, Fukui K, Masuda T, Mizohata E, Miyahara I, Kurauchi I, Murakami T, Matsunaga H, Montawa Y, Nakajima N, Oozeki T, Sakai K, Son T, Higuchi T, Sunami T, Kimura T, Tono K, Tanaka T, Sugahara M, Arima T, Fangjia L, Kang J, Tanaka R, Iwata S, Nango E, Tosha T, Yano T, Tanizawa K, Okajima T.   +29 more
europepmc   +1 more source

Fixed-target serial crystallography at the Structural Biology Center. [PDF]

J Synchrotron Radiat, 2022
Sherrell DA, Lavens A, Wilamowski M, Kim Y, Chard R, Lazarski K, Rosenbaum G, Vescovi R, Johnson JL, Akins C, Chang C, Michalska K, Babnigg G, Foster I, Joachimiak A.   +14 more
europepmc   +1 more source

Serial crystallography with multi-stage merging of thousands of images. [PDF]

Acta Crystallogr F Struct Biol Commun, 2022
Soares AS, Yamada Y, Jakoncic J, McSweeney S, Sweet RM, Skinner J, Foadi J, Fuchs MR, Schneider DK, Shi W, Andi B, Andrews LC, Bernstein HJ.   +12 more
europepmc   +1 more source

Serial protein crystallography in cellulo

Elucidation of high-resolution three-dimensional protein structures via X-ray crystallography requires protein crystals for signal enhancement. Protein crystals have been observed in living cells from all domains of life. This cumulative dissertation refines and expands a systematic approach for crystallization of recombinantly introduced proteins in ...
openaire   +2 more sources

Probing the modulation of enzyme kinetics by multi-temperature, time-resolved serial crystallography. [PDF]

Nat Commun
Schulz EC, Prester A, von Stetten D, Gore G, Hatton CE, Bartels K, Leimkohl JP, Schikora H, Ginn HM, Tellkamp F, Mehrabi P.   +10 more
europepmc   +1 more source