Results 121 to 130 of about 3,847 (182)

Minimized sample consumption for time-resolved serial crystallography applied to the redox cycle of human NQO1

Communications Chemistry
Sample consumption for serial femtosecond crystallography with X-ray free electron lasers remains a major limitation preventing broader use in macromolecular crystallography.
Diandra Doppler, Alice Grieco, Domin Koh, Abhik Manna, Adil Ansari, Roberto Alvarez, Konstantinos Karpos, Hung Le, Mukul Sonker, Gihan K. Ketawala, Samira Mahmud, Isabel Quereda-Moraleda, Sayantee Sen, Angel L. Pey, Romain Letrun, Katerina Dörner, Jayanath C. P. Koliyadu, Raphael de Wijn, Johan Bielecki, Huijong Han, Chan Kim, Faisal H. M. Koua, Adam Round, Abhisakh Sarma, Tokushi Sato, Christina Schmidt, Mohammad Vakili, Dmitrii Zabelskii, Richard Bean, Adrian P. Mancuso, Joachim Schulz, Raimund Fromme, Milagros Medina, Thomas D. Grant, Petra Fromme, Richard A. Kirian, Sabine Botha, Jose Manuel Martin-Garcia, Alexandra Ros   +38 more
doaj   +1 more source

Preliminary Serial Femtosecond Crystallography Studies of Myoglobin from Equine Skeletal Muscle

Crystals
Myoglobin (Mb), a heme-containing protein, plays crucial roles in storing and transporting oxygen in muscle cells. Various Mb structures have been extensively determined using conventional cryogenic crystallography, providing valuable information for ...
Jaehyun Park, Sehan Park, Ki Hyun Nam
doaj   +1 more source

Convergent-beam attosecond x-ray crystallography

Structural Dynamics
Sub-ångström spatial resolution of electron density coupled with sub-femtosecond to few-femtosecond temporal resolution is required to directly observe the dynamics of the electronic structure of a molecule after photoinitiation or some other ultrafast ...
Henry N. Chapman, Chufeng Li, Saša Bajt, Mansi Butola, J. Lukas Dresselhaus, Dmitry Egorov, Holger Fleckenstein, Nikolay Ivanov, Antonia Kiene, Bjarne Klopprogge, Viviane Kremling, Philipp Middendorf, Dominik Oberthuer, Mauro Prasciolu, T. Emilie S. Scheer, Janina Sprenger, Jia Chyi Wong, Oleksandr Yefanov, Margarita Zakharova, Wenhui Zhang   +19 more
doaj   +1 more source

Serial millisecond crystallography of membrane and soluble protein microcrystals using synchrotron radiation

IUCrJ, 2017
Crystal structure determination of biological macromolecules using the novel technique of serial femtosecond crystallography (SFX) is severely limited by the scarcity of X-ray free-electron laser (XFEL) sources. However, recent and future upgrades render
Jose M. Martin-Garcia, Chelsie E. Conrad, Garrett Nelson, Natasha Stander, Nadia A. Zatsepin, James Zook, Lan Zhu, James Geiger, Eugene Chun, David Kissick, Mark C. Hilgart, Craig Ogata, Andrii Ishchenko, Nirupa Nagaratnam, Shatabdi Roy-Chowdhury, Jesse Coe, Ganesh Subramanian, Alexander Schaffer, Daniel James, Gihan Ketwala, Nagarajan Venugopalan, Shenglan Xu, Stephen Corcoran, Dale Ferguson, Uwe Weierstall, John C. H. Spence, Vadim Cherezov, Petra Fromme, Robert F. Fischetti, Wei Liu   +29 more
doaj   +1 more source

The scaling of exploding liquid jets under intense X-ray pulses

, 2018
A general scaling of the evolution of an exploding liquid jet under an ultra short and intense X-ray pulse from a X-ray free electron laser (XFEL) is proposed.
Ganan-Calvo, Alfonso M.
core   +1 more source

Serial femtosecond crystallography structure of cytochrome c oxidase at room temperature

Scientific Reports, 2017
Cytochrome c oxidase catalyses the reduction of molecular oxygen to water while the energy released in this process is used to pump protons across a biological membrane.
Rebecka Andersson, Cecilia Safari, Robert Dods, Eriko Nango, Rie Tanaka, Ayumi Yamashita, Takanori Nakane, Kensuke Tono, Yasumasa Joti, Petra Båth, Elin Dunevall, Robert Bosman, Osamu Nureki, So Iwata, Richard Neutze, Gisela Brändén   +15 more
doaj   +1 more source

Review of serial femtosecond crystallography including the COVID-19 pandemic impact and future outlook. [PDF]

Structure, 2023
Botha S, Fromme P.
europepmc   +1 more source

Detection of a Geminate Photoproduct of Bovine Cytochrome c Oxidase by Time-Resolved Serial Femtosecond Crystallography. [PDF]

J Am Chem Soc, 2023
Ishigami I, Carbajo S, Zatsepin N, Hikita M, Conrad CE, Nelson G, Coe J, Basu S, Grant T, Seaberg MH, Sierra RG, Hunter MS, Fromme P, Fromme R, Rousseau DL, Yeh SR.   +15 more
europepmc   +1 more source

Low-pass spectral analysis of time-resolved serial femtosecond crystallography data. [PDF]

Struct Dyn, 2023
Casadei CM, Hosseinizadeh A, Bliven S, Weinert T, Standfuss J, Fung R, Schertler GFX, Santra R.   +7 more
europepmc   +1 more source

Serial Femtosecond Crystallography Reveals that Photoactivation in a Fluorescent Protein Proceeds via the Hula Twist Mechanism. [PDF]

J Am Chem Soc, 2023
Fadini A, Hutchison CDM, Morozov D, Chang J, Maghlaoui K, Perrett S, Luo F, Kho JCX, Romei MG, Morgan RML, Orr CM, Cordon-Preciado V, Fujiwara T, Nuemket N, Tosha T, Tanaka R, Owada S, Tono K, Iwata S, Boxer SG, Groenhof G, Nango E, van Thor JJ.   +22 more
europepmc   +1 more source