Results 121 to 130 of about 7,626 (235)
Protein Science, Volume 35, Issue 6, June 2026.Abstract Membrane fusion between HIV and host cells requires interaction between the N‐terminal and C‐terminal repeat regions (NHR and CHR) of the gp41 envelope subunit. A deep hydrophobic pocket (HP) on the surface of NHR is considered crucial in this interaction.
Daniel Polo‐Megías +9 more
wiley +1 more source
IUCrJTime-resolved X-ray crystallography is undergoing a renaissance due to the development of serial crystallography at synchrotron and XFEL beamlines. Crucial to such experiments are efficient and effective methods for uniformly initiating time-dependent ...
Peter Smyth +20 more
doaj +1 more source
Elucidating metal–organic framework structures using synchrotron serial crystallography
CrystEngCommMetal organic frameworks (MOFs) are porous crystalline materials that display a wide variety of physical and chemical properties.
de Zitter, Elke +9 more
openaire +4 more sources
Protein Science, Volume 35, Issue 6, June 2026.Abstract The intrinsic dynamic asymmetry between homologous PDZ domains in multidomain scaffold proteins offers insight into how they achieve multivalent partner recognition. Through a systematic x‐ray crystallographic analysis of tandem PDZ1–PDZ2 domains in human syntenin‐1 (SDCBP/MDA‐9), we solved nine high‐resolution structures and uncovered ...
Natsuno Ando +8 more
wiley +1 more source
Stabilizing Plasmodium falciparum proteins for small molecule drug discovery
Protein Science, Volume 35, Issue 6, June 2026.Abstract Early‐stage drug discovery relies on the availability of stable protein for reliable biophysical characterization of ligand binding. However, many Plasmodium falciparum proteins are challenging to produce in heterologous systems, which limits their experimental utility.
Marius Amann +3 more
wiley +1 more source
Structural Analysis and Inhibitor Modeling of Bacterioferritin From Brucella abortus
Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 6, Page 1170-1181, June 2026.ABSTRACT Iron homeostasis in various pathogenic bacteria is regulated by bacterioferritins (Bfr) which function to store Fe3+ and release Fe2+ as needed for metabolic processes. The Bfr structure consists of 18 kDa subunits in which dimer pairs bind a heme molecule and are assembled into a highly symmetrical 24‐meric spherical structure with an ...
Lijun Liu +9 more
wiley +1 more source
Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 6, Page 1245-1258, June 2026.ABSTRACT We present the first x‐ray crystallographic structural evidence of an archaeal DNA ligase showing the AMP covalent adduct together with further cofactor hydrolysis, capturing a transient intermediary in the first step of the ligation reaction, triggered by the pyrophosphate hydrolysis.
A. X. Quintana‐Armas +3 more
wiley +1 more source
Asymmetry of the Ferroelectric Phase Transition in BaTiO3
Advanced Materials, Volume 38, Issue 25, 4 May 2026.Phase transitions are typically assumed to behave identically in forward and reverse. This work shows that in the ferroelectric material barium titanate this is not true: heating drives an abrupt, first‐order jump, while cooling gives a smooth, continuous change.
Asaf Hershkovitz +14 more
wiley +1 more source
ChemistryEurope, Volume 4, Issue 5, May 2026.Polyoxometalates (POMs), illustrated as lemon‐like cars racing along a winding road, symbolize the accelerating progress of POM research toward technological applications. Global research communities, recent advances, and emerging opportunities highlight how coordinated efforts drive the transition of POM science from molecular discovery to deployable ...
Kirill Monakhov +15 more
wiley +1 more source
SAD phasing of XFEL data depends critically on the error model. [PDF]
, 2019 A nonlinear least-squares method for refining a parametric expression describing the estimated errors of reflection intensities in serial crystallographic (SX) data is presented.
Bhowmick, Asmit +5 more
core +1 more source