Results 261 to 270 of about 938,109 (291)

Identification of covalent inhibitors of Staphylococcus aureus serine hydrolases important for virulence and biofilm formation. [PDF]

open access: yesNat Commun
Upadhyay T   +18 more
europepmc   +1 more source

Identification and genetic analysis of candidate genes for resistance against <i>Phytophthora sojae</i> in soybean using a genome-wide association study. [PDF]

open access: yesFront Plant Sci
Park HR   +13 more
europepmc   +1 more source

Metabolic Profile Associated With Encystation in Acanthamoeba. [PDF]

open access: yesJ Eukaryot Microbiol
Cirelli C   +8 more
europepmc   +1 more source
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Mechanism of eukaryotic serine racemase-catalyzed serine dehydration

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2020
Eukaryotic serine racemase (SR) is a pyridoxal 5'-phosphate enzyme belonging to the Fold-type II group, which catalyzes serine racemization and is responsible for the synthesis of D-Ser, a co-agonist of the N-methyl-d-aspartate receptor. In addition to racemization, SR catalyzes the dehydration of D- and L-Ser to pyruvate and ammonia.
Hisashi Hemmi   +8 more
openaire   +3 more sources

Reactions of Serine Palmitoyltransferase with Serine and Molecular Mechanisms of the Actions of Serine Derivatives as Inhibitors

Biochemistry, 2004
Serine palmitoyltransferase (SPT) is a key enzyme in sphingolipid biosynthesis and catalyzes the decarboxylative condensation of L-serine and palmitoyl coenzyme A to 3-ketodihydrosphingosine. We have succeeded in the overproduction of a water-soluble homodimeric SPT from Sphingomonas paucimobilis EY2395(T) in Escherichia coli.
Hiroyuki Kagamiyama   +2 more
openaire   +3 more sources

Synthesis of photodeprotectable serine derivatives. “Caged serine”

Bioorganic & Medicinal Chemistry Letters, 1992
Abstract The synthesis of O-(4,5-dimethoxy-2-nitrobenzyl)serine has been accomplished by treatment of an FMOC-aziridinecarboxylate with nitroveratryl alcohol followed by hydrolysis. Irradiation with a Pyrex-filtered 450W Hanovia lamp releases serine with a half-life of 4.4 min. o-Nitrobenzyl serinate is prepared by direct esterification.
David S. Nunn, Michael C. Pirrung
openaire   +2 more sources

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