Discovery and biochemical characterization of the D-aspartyl endopeptidase activity of the serine protease LACTB [PDF]
Journal of Biological ChemistryNonenzymatic D-isomerization of aspartic acid in proteins has been observed in lesions associated with age-related diseases, including cataracts and Alzheimer's disease.
Genta Itô, Naoko Utsunomiya-Tate
exaly +5 more sources
Genetic Biodiversity and Posttranslational Modifications of Protease Serine Endopeptidase in Different Strains of Sordaria fimicola. [PDF]
Biomed Res Int, 2023 Genetic variations (mutation, crossing over, and recombination) act as a source for the gradual alternation in phenotype along a geographic transect where the environment changes.
Naureen U +5 more
europepmc +4 more sources
Ecotoxicology and Environmental Safety, 2020 Cadmium, a toxic heavy metal, is a persistent environmental contaminant with irreversible toxicity to aquatic organisms. Chironomus plumosus, a natural species, is the largest sediment-burrowing aquatic midge in freshwater environments. In this study, we
Kiyun Park, Ihn-Sil Kwak
exaly +4 more sources
Arterivirus Serine Endopeptidase [PDF]
Handbook of Proteolytic Enzymes, 2012 E. Snijder, A. Gorbalenya
europepmc +3 more sources
A Cytosolic Serine Endopeptidase from Trypanosoma cruzi Is Required for the Generation of Ca2+ Signaling in Mammalian Cells [PDF]
Journal of Cell Biology, 1997 An early event in the Trypanosoma cruzi cell invasion process, the recruitment of host lysosomes, led us to investigate the involvement of signal transduction.
Barbara A Burleigh +2 more
exaly +4 more sources
Specific fluorogenic substrates for neprilysin (neutral endopeptidase, EC 3.4.24.11) which are highly resistant to serine- and metalloproteases [PDF]
Brazilian Journal of Medical and Biological Research, 1997 Two intramolecularly quenched fluorogenic peptides containing o-aminobenzoyl (Abz) and ethylenediamine 2,4-dinitrophenyl (EDDnp) groups at amino- and carboxyl-terminal amino acid residues, Abz-DArg-Arg-Leu-EDDnp (Abz-DRRL-EDDnp) and Abz-DArg-Arg-Phe ...
M.A.S. Medeiros +4 more
doaj +10 more sources
Biomolecules, 2020 The aggregation of α-synuclein (α-Syn) is a characteristic of Parkinson’s disease (PD). α-Syn oligomerization/aggregation is accelerated by the serine peptidase, prolyl oligopeptidase (POP).
Gabriel S. Santos +4 more
doaj +2 more sources
Safety evaluation of the food enzyme serine endopeptidase from the genetically modified Aspergillus niger strain NZYM‐MG [PDF]
EFSA JournalThe food enzyme serine endopeptidase (EC 3.4.21) is produced with the genetically modified Aspergillus niger strain NZYM‐MG by Novozymes A/S. The genetic modifications do not give rise to safety concerns.
EFSA Panel on Food Enzymes (FEZ) +14 more
doaj +2 more sources
Frontiers in Immunology, 2022 Several serine proteases have been linked to autoimmune disorders and tumour initiation although the mechanisms are not fully understood. Activation of the kynurenine pathway enzyme indoleamine-2,3-dioxygenase (IDO1) modulates cellular activity in the ...
Felix I. L. Clanchy +6 more
doaj +2 more sources
Comparative Transcriptome Analysis Reveals Expression of Defense Pathways and Specific Protease Inhibitor Genes in Solanum lycopersicum in Response to Feeding by Tuta absoluta [PDF]
InsectsUnderstanding plant-insect interactions can help control the harm of herbivorous pests. According to transcriptome data, transcripts of Solanum lycopersicum responding to feeding by Tuta absoluta were screened for important endopeptidase inhibitors ...
Yan Zhou +4 more
doaj +2 more sources