Results 91 to 100 of about 122,475 (202)

Subunit III of ruminant procarboxypeptidase A‐S6 complexes and pancreatic proteases E a new family of pancreatic serine endopeptidases?

FEBS Letters, 1988
Subunit III (BSIII) of the bovine ternary complex of procarboxypeptidase A‐S6 (PCPA‐S6), a defective serine endopeptidase‐like protein, actively synthesized by the pancreas of some ruminant species, is highly homologous to human protease E (HPE). Both proteins possess the same atypical disulfide bridge in position 98–99b.
Cambillau, Christian, Kerfelec, Brigitte, Sciaky, Martine, Chapus, Catherine   +3 more
openaire   +2 more sources

A Short and Efficient Synthesis of l-5,5,5,5‘,5‘,5‘-hexafluoroleucine from N-Cbz-l-Serine

, 2016
5,5,5,5‘,5‘,5‘-Hexafluoroleucine (6), a fluorous analogue of leucine, is of considerable interest as a building block in the design of fluorous proteins and peptides.
James T. Anderson (218373), Peter L. Toogood (2384689), E. Neil G. Marsh (1344120)   +2 more
core   +1 more source

Effects of D-amino acid oxidase inhibition on memory performance and long-term potentiation in vivo [PDF]

, 2013
N-methyl-d-aspartate receptor (NMDAR) activation can initiate changes in synaptic strength, evident as long-term potentiation (LTP), and is a key molecular correlate of memory formation.
Kerry L. Spear, Seth C. Hopkins, Hopkins, Seth C., David C. Spanswick, Heffernan, Michele L. R., Campbell, Una C., Ross D. Jeggo, Spear, Kerry L., Varney, Mark A., Michele L. R. Heffernan, Thomas H. Large, Spanswick, David C., Jeggo, Ross D., Mark A. Varney, Large, Thomas H., Una C. Campbell   +15 more
core   +1 more source

Stage-specific transcriptomic analysis reveals insights into the development, reproduction and biological function of allergens in the European house dust mite Dermatophagoides pteronyssinus

BMC Genomics
Background House dust mites (HDMs) such as Dermatophagoides pteronyssinus are major allergy elicitors worldwide, yet their gene expression across developmental stages remains underexplored.
José Cristian Vidal-Quist, Félix Ortego, Bart N. Lambrecht, Stephane Rombauts, Pedro Hernández-Crespo   +4 more
doaj   +1 more source

Characterization of endopeptidases from the midgut of Morimus funereus (Coleoptera: Cerambycidae) larvae

, 2014
— Application of specific chromogenic substrates, use of class-specific inhibitors, and zymogram analysis enabled us to identify several peptidase classes in extracts of the midgut of Morimus funereus larvae. Zymogram analysis with gelatin as a peptidase
Nataša Božić, Vera Nenadović, Biljana Dojnov, Jelisaveta Ivanović, Ra Milovanović, Z. Vujčić   +5 more
core  

Two novel IgG endopeptidases of Streptococcus equi

, 2009
Streptococcus equi ssp. equi causes strangles, a highly contagious and serious disease in the upper respiratory tract of horses. Streptococcus equi ssp. zooepidemicus, another subspecies of this genus, is regarded as an opportunistic commensal in horses.
Hulting, Greta,, Guss, Bengt,, Sveriges lantbruksuniversitet., Frykberg, Lars,   +3 more
core   +2 more sources

Functional studies of serine/threonine protein kinase signalling in Mycobacterium tuberculosis. [PDF]

, 2006
Fork-head associated (FHA) domains function in the assembly of signalling complexes through specific interactions with phospho-threonine motifs. FHA domains are found in eukaryotes, and intriguingly in a subset of bacterial species including Mycobacteria
Patel, D.P.
core  

Site-specific serine incorporation by Lif and Epr into positions 3 and 5 of the Staphylococcal peptidoglycan interpeptide bridge

, 2000
The FemAB-like factors Lif and Epr confer resistance to glycylglycine endopeptidases lysostaphin and Ale-1, respectively, by incorporating serine residues into the staphylococcal peptidoglycan interpeptide bridges specifically at positions 3 and 5.
Brigitte Berger-Bächi, Claudio Mori, Mori, C, Werner Schröder, Berger-Bächi, B, Ehlert, K, Schröder, W, Tschierske, M, Kerstin Ehlert, Martin Tschierske   +9 more
core   +1 more source

ROC plots evaluating the performance of DeepDrug3D against the peptidase dataset.

, 2019
The performance is assessed individually for five groups of enzymes, serine endopeptidases (EC 3.4.21), cysteine endopeptidases (EC 3.4.22), aspartic endopeptidases (EC 3.4.23), metalloendopeptidases (EC 3.4.24), and threonine endopeptidases (EC 3.4.25).
Rajiv Gandhi Govindaraj (204730), Michal Brylinski (119287), Limeng Pu (6293801), Jeffrey Mitchell Lemoine (6293804), Hsiao-Chun Wu (192195)   +4 more
core   +1 more source

Inhibition of the Alanine-Serine-Cysteine‑1 Transporter by BMS-466442

, 2019
Experiment and modeling were combined to understand inhibition of the alanine-serine-cysteine-1 (asc1) transporter. The structure–activity relationship (SAR) was explored with synthesis of analogues of BMS-466442.
Andrés A. Trabanco, Aránzazu Garcı́a Molina (6458399), Gary Tresadern, Susana Conde-Ceide, Susana Conde-Ceide (1326192), Hilde Lavreysen (836508), Leonardo Pardo (206449), Ivan R. Torrecillas, Andrés A. Trabanco (1367745), Ana Isabel de Lucas (2030461), Gary Tresadern (836509), Hilde Lavreysen, Ivan R. Torrecillas (2228977), Ana Isabel de Lucas, Aránzazu Garcı́a Molina, Leonardo Pardo   +15 more
core   +1 more source