Results 91 to 100 of about 20,933 (225)

Genetic risk variants implicate impaired maintenance and repair of periodontal tissues as causal for periodontitis—A synthesis of recent findings

Periodontology 2000, EarlyView.
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer, Luigi Nibali, Noha Zoheir, Niki M. Moutsopoulos, Bruno G. Loos   +4 more
wiley   +1 more source

Amino acid sequence of the chymotryptic protease II from the larvae of the hornet, Vespa crabro [PDF]

, 1916
The covalent structure of the chymotrypsin II from the larvae of the hornet, Vespa crabro, has been determined. The sequence has been deduced from 3 sets of overlapping peptides generated by trypsin after modification of the lysine or arginine residues ...
De Haë, Law, Zwilling, Jany, Toi, Jany, Jany, Jany, Woodbury, Titani, Dayhoff   +10 more
core   +5 more sources

Traversing the effects of ploidy changes in different Eragrostis curvula genotypes through high‐throughput RNA sequencing

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Polyploidization has played a key role in plant genome evolution. Eragrostis curvula (Schrad.) Ness, a perennial forage grass species of the Poaceae family, is an excellent model for investigating genome duplication due to its natural variation in ploidy levels.
D. F. Santoro, J. Carballo, M. C. Pasten, C. A. Gallo, E. Albertini, V. Echenique   +5 more
wiley   +1 more source

Methodological Evaluation of Carbapenemase Detection by Different Methods

Polish Journal of Microbiology
The global proliferation of carbapenemase-producing bacteria (CPB) has garnered significant attention worldwide. Early diagnosis of CPB and accurate identification of carbapenemases are crucial for preventing the spread of CPB and ensuring targeted ...
Gao Nana, Zhou Jing, Li Ge, Liu Runde, Lu Guoping, Shen Jilu   +5 more
doaj   +1 more source

Positional scanning and computational modeling reveal determinants of legumain transpeptidase activity

Protein Science, Volume 35, Issue 5, May 2026.
Abstract Legumain is a lysosomal cysteine protease that plays a central role in antigen processing for MHC class II presentation. Beyond its canonical proteolytic activity, legumain can also function as a peptide ligase or transpeptidase. This non‐canonical activity becomes particularly relevant under pathophysiological conditions such as cancer and ...
Rupert Klaushofer, Sven O. Dahms, Hans Brandstetter, Elfriede Dall   +3 more
wiley   +1 more source

Protein traffic in parasites and mammalian cells. Proceedings of a workshop [PDF]

, 2014
The International Laboratory for Research on Animal Diseases (ILRAD) has recently developed interests in several areas of cell biology and biochemistry that are relevant to trypanosomiasis and theileriosis (East Coast Fever (ECF)).
Lenahan, J.K., Lonsdale-Eccles, J.C.
core  

Aluminum modulation of proteolytic activities [PDF]

, 2002
The effect of aluminum ions on the activity of proteolyic activities, mainly serine proteases and calpains, has been examined. Aluminum affects the biological activity of proteolytic activities either through a direct effect on the enzyme molecule or ...
Angeletti, M, Coletta, M, Eleuteri, AM, Fioretti, E, Gioia, M, Lupidi, G, Marini, S   +6 more
core   +1 more source

A Bifunctional Protease Cleaves the Leader Peptide in the Biosynthesis of Class I Microviridins

ChemBioChem, Volume 27, Issue 7, 14 April 2026.
Biochemical characterization of the peptidase candidate NosP reveals bifunctional endo‐ and aminopeptidase activity in the leader peptide removal of class I microviridins from Nostoc punctiforme. The discovery of the first leader‐processing peptidase from microviridin biosynthesis may pave the way for the efficient production and bioengineering of ...
Nico Brüssow, Stella Scholz, Antje Stindt, Vincent Wiebach, Tino Damaszek, Roderich D. Süssmuth, Elke Dittmann, Martin Baunach   +7 more
wiley   +1 more source

ZapA, a possible virulence factor from Proteus mirabilis exhibits broad protease substrate specificity [PDF]

, 2001
The opportunistic bacterium Proteus mirabilis secretes a metalloprotease, ZapA, considered to be one of its virulence factors due to its IgA-degrading activity. However, the substrate specificity of this enzyme has not yet been fully characterized.
Anéas, M.a.f., Fernandes, B.l., Juliano, Luiz, Lebrun, Ivo, Palma, M.s., Portaro, Fernanda Calheta Vieira   +5 more
core   +4 more sources

Characterization of a prolyl endopeptidase from Flavobacterium meningosepticum. Complete sequence and localization of the active-site serine.

Journal of Biological Chemistry, 1992
A prolyl endopeptidase was purified from Flavobacterium meningosepticum. It was digested with trypsin. Two oligonucleotides, based on tryptic peptide sequences and used in PCR experiments, amplified a 300-base pair (bp) fragment. A 2.4-kilobase EcoRI fragment that hybridized to the 300-bp probe was cloned in lambda ZAP and sequenced from both strands ...
Chevallier, S., Goeltz, P., Thibault, P., Banville, D., Gagnon, Joanne   +4 more
openaire   +3 more sources