Results 61 to 70 of about 5,999 (124)

The Factors Involved in Plant–Insect–Microbe Interactions Expanded: Genome Analysis and Description of Frigoribacterium adelgis sp. nov.

Environmental Microbiology Reports, Volume 18, Issue 1, February 2026.
Aerobic Actinobacteria belonging to the genus Frigoribacterium were isolated from adelgid Adelges (Aphrastasia) pectinatae collected from a Korean fir tree. Genomic analysis showed that these bacteria encode a range of factors that may be involved in the interactions between Frigoribacterium strains, adelgids and/or Korean fir trees.
Gustė Tamošiūnaitė, Jekaterina Havelka, Raimonda Baranauskienė, Justas Lazutka, Nomeda Kuisiene   +4 more
wiley   +1 more source

CASP16 Protein Monomer Structure Prediction Assessment

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 1, Page 86-105, January 2026.
ABSTRACT The assessment of monomer targets in the Critical Assessment of Structure Prediction Round 16 (CASP16) underscores that the problem of single‐domain protein fold prediction is nearly solved—no target folds were incorrectly predicted across all Evaluation Units.
Rongqing Yuan, Jing Zhang, Andriy Kryshtafovych, R. Dustin Schaeffer, Jian Zhou, Qian Cong, Nick V. Grishin   +6 more
wiley   +1 more source

ICESag37, a Novel Integrative and Conjugative Element Carrying Antimicrobial Resistance Genes and Potential Virulence Factors in Streptococcus agalactiae

Frontiers in Microbiology, 2017
ICESag37, a novel integrative and conjugative element carrying multidrug resistance and potential virulence factors, was characterized in a clinical isolate of Streptococcus agalactiae. Two clinical strains of S.
Kaixin Zhou, Lianyan Xie, Lizhong Han, Xiaokui Guo, Yong Wang, Jingyong Sun   +5 more
doaj   +1 more source

Functional Relevance of CASP16 Nucleic Acid Predictions as Evaluated by Structure Providers

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 1, Page 51-78, January 2026.
ABSTRACT Accurate biomolecular structure prediction enables the prediction of mutational effects, the speculation of function based on predicted structural homology, the analysis of ligand binding modes, experimental model building, and many other applications.
Rachael C. Kretsch, Reinhard Albrecht, Ebbe S. Andersen, Hsuan‐Ai Chen, Wah Chiu, Rhiju Das, Jeanine G. Gezelle, Marcus D. Hartmann, Claudia Höbartner, Yimin Hu, Shekhar Jadhav, Philip E. Johnson, Christopher P. Jones, Deepak Koirala, Emil L. Kristoffersen, Eric Largy, Anna Lewicka, Cameron D. Mackereth, Marco Marcia, Michela Nigro, Manju Ojha, Joseph A. Piccirilli, Phoebe A. Rice, Heewhan Shin, Anna‐Lena Steckelberg, Zhaoming Su, Yoshita Srivastava, Liu Wang, Yuan Wu, Jiahao Xie, Nikolaj H. Zwergius, John Moult, Andriy Kryshtafovych   +32 more
wiley   +1 more source

Mitigating genetic instability caused by the excision activity of the phiC31 integrase in Streptomyces

Applied and Environmental Microbiology
Over the past three decades, the integrase (Int) from Streptomyces phage phiC31 has become a valuable genome engineering tool across various species. phiC31 Int was thought to mediate unidirectional site-specific integration (attP × attB to attL and attR)
Yadan Duan, Zhangliang Liu, Xiaofang Huang, Lu Xu, Xianxue Wang, Hao Liu, Zhoujie Xie   +6 more
doaj   +1 more source

Engineering Conditional Transgene Expression in Nicotiana benthamiana

Plant Biotechnology Journal, Volume 24, Issue 1, Page 18-30, January 2026.
ABSTRACT Nicotiana benthamiana has emerged as a premier plant biofactory for recombinant protein and metabolite production due to its high metabolic versatility, ease of cultivation and permissiveness to transient expression vectors. However, challenges such as transgene silencing, low yields and metabolic toxicity limit its scalability. Synthetic gene
Elena Garcia‐Perez, Marta Vazquez‐Vilar, Diego Orzaez   +2 more
wiley   +1 more source

Health Benefits and Therapeutic Potential of Quercetin

Journal of Food Biochemistry, Volume 2026, Issue 1, 2026.
Quercetin, a polyphenolic compound prevalent in many fruits, vegetables, and other dietary sources, has attracted considerable interest due to its extensive health benefits. This review examines its diverse biological properties, particularly its antioxidant and anti‐inflammatory effects. The study integrates recent scientific findings to elucidate the
Mahendra Aryal, Kim Wei Chan
wiley   +1 more source

Drug Discovery Applications of Nitroso (Hetero)Arene Derivatives

ChemPlusChem, Volume 90, Issue 12, December 10, 2025.
Nitroso (hetero)aromatic compounds are bioactive molecules with antiviral, anticancer, neuroprotective, and antimicrobial properties. This review highlights their mechanisms of action—oxidative stress, DNA damage, and enzyme inhibition—alongside synthesis, structure–activity relationships, and toxicity challenges, offering insight into their ...
Silvia Roscales, Aurelio G. Csáky
wiley   +1 more source

A history-dependent integrase recorder of plant gene expression with single-cell resolution

Nature Communications
During development, most cells experience a progressive restriction of fate that ultimately results in a fully differentiated mature state. Understanding more about the gene expression patterns that underlie developmental programs can inform engineering ...
Cassandra J. Maranas, Wesley George, Sarah K. Scallon, Sydney VanGilder, Jennifer L. Nemhauser, Sarah Guiziou   +5 more
doaj   +1 more source

A New Inovirus from the Human Blood Encodes Proteins with Nuclear Subcellular Localization

Viruses
Viruses infecting bacteria (bacteriophages) represent the most abundant viral particles in the human body. They participate in the control of the human-associated bacterial communities and play an important role in the dissemination of virulence genes ...
Nikolay Popgeorgiev, Mart Krupovic, Julien Hiblot, Laura Fancello, Sonia Monteil-Bouchard, Christelle Desnues   +5 more
doaj   +1 more source