Results 81 to 90 of about 6,315 (155)

Diversity of FAAL enzymes and prediction of their substrate specificity using FAALPred

Protein Science, Volume 35, Issue 2, February 2026.
Abstract FAALs (fatty acyl‐AMP ligases) recruit and incorporate fatty acids during the biosynthesis of secondary metabolites. Their diversity, distribution, and substrate specificity remain poorly understood, which limits functional predictions from sequence data.
Anne Liong, Leandro de Mattos Pereira, Pedro N. Leão   +2 more
wiley   +1 more source

Comparison and optimization of ten phage encoded serine integrases for genome engineering in Saccharomyces cerevisiae [PDF]

BMC Biotechnology, 2016
Phage-encoded serine integrases, such as ϕC31 integrase, are widely used for genome engineering but have not been optimized for use in Saccharomyces cerevisiae although this organism is a widely used organism in biotechnology.The activities of derivatives of fourteen serine integrases that either possess or lack a nuclear localization signal were ...
Xu, Zhengyao, Brown, William
openaire   +3 more sources

Diversity, Function and Activity of DNA Viruses in the Qiangyong Proglacial Lake Sediment, the Tibetan Plateau

Environmental Microbiology Reports, Volume 18, Issue 1, February 2026.
This study identified DNA viruses from Qiangyong proglacial lake sediments on the Tibetan Plateau, revealing a highly diverse and previously uncharacterized viral community. These viruses influence microbial community structure and function by infecting key nutrient‐transforming taxa and encoding auxiliary metabolic genes that modulate host metabolism.
Yang Zhao, Meiling Feng, Hongfei Chi, Keshao Liu, Rong Wen, Weizhen Zhang, Pengfei Liu   +6 more
wiley   +1 more source

The Factors Involved in Plant–Insect–Microbe Interactions Expanded: Genome Analysis and Description of Frigoribacterium adelgis sp. nov.

Environmental Microbiology Reports, Volume 18, Issue 1, February 2026.
Aerobic Actinobacteria belonging to the genus Frigoribacterium were isolated from adelgid Adelges (Aphrastasia) pectinatae collected from a Korean fir tree. Genomic analysis showed that these bacteria encode a range of factors that may be involved in the interactions between Frigoribacterium strains, adelgids and/or Korean fir trees.
Gustė Tamošiūnaitė, Jekaterina Havelka, Raimonda Baranauskienė, Justas Lazutka, Nomeda Kuisiene   +4 more
wiley   +1 more source

A history-dependent integrase recorder of plant gene expression with single-cell resolution

Nature Communications
During development, most cells experience a progressive restriction of fate that ultimately results in a fully differentiated mature state. Understanding more about the gene expression patterns that underlie developmental programs can inform engineering ...
Cassandra J. Maranas, Wesley George, Sarah K. Scallon, Sydney VanGilder, Jennifer L. Nemhauser, Sarah Guiziou   +5 more
doaj   +1 more source

A New Inovirus from the Human Blood Encodes Proteins with Nuclear Subcellular Localization

Viruses
Viruses infecting bacteria (bacteriophages) represent the most abundant viral particles in the human body. They participate in the control of the human-associated bacterial communities and play an important role in the dissemination of virulence genes ...
Nikolay Popgeorgiev, Mart Krupovic, Julien Hiblot, Laura Fancello, Sonia Monteil-Bouchard, Christelle Desnues   +5 more
doaj   +1 more source

Functional significance of SRJ domain mutations in CITED2.

PLoS ONE, 2012
CITED2 is a transcriptional co-activator with 3 conserved domains shared with other CITED family members and a unique Serine-Glycine Rich Junction (SRJ) that is highly conserved in placental mammals.
Chiann-mun Chen, Jamie Bentham, Catherine Cosgrove, Jose Braganca, Ana Cuenda, Simon D Bamforth, Jürgen E Schneider, Hugh Watkins, Bernard Keavney, Benjamin Davies, Shoumo Bhattacharya   +10 more
doaj   +1 more source

CASP16 Protein Monomer Structure Prediction Assessment

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 1, Page 86-105, January 2026.
ABSTRACT The assessment of monomer targets in the Critical Assessment of Structure Prediction Round 16 (CASP16) underscores that the problem of single‐domain protein fold prediction is nearly solved—no target folds were incorrectly predicted across all Evaluation Units.
Rongqing Yuan, Jing Zhang, Andriy Kryshtafovych, R. Dustin Schaeffer, Jian Zhou, Qian Cong, Nick V. Grishin   +6 more
wiley   +1 more source

Tanglegram of host species lineages and phylogeny of serine integrases in prophages and ICEs.

, 2019
A tanglegram of serine integrases from ICEs and prophages with the species lineages plotted on the left and tyrosine integrase phylogeny plotted on the right. Connections are drawn between a species and the serine integrase(s) found in that species.
Andrew Brantley Hall (8119820), Xiaofang Jiang (3799252), Eric J. Alm (7485080), Ramnik J. Xavier (153776)   +3 more
core   +1 more source

Functional Relevance of CASP16 Nucleic Acid Predictions as Evaluated by Structure Providers

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 1, Page 51-78, January 2026.
ABSTRACT Accurate biomolecular structure prediction enables the prediction of mutational effects, the speculation of function based on predicted structural homology, the analysis of ligand binding modes, experimental model building, and many other applications.
Rachael C. Kretsch, Reinhard Albrecht, Ebbe S. Andersen, Hsuan‐Ai Chen, Wah Chiu, Rhiju Das, Jeanine G. Gezelle, Marcus D. Hartmann, Claudia Höbartner, Yimin Hu, Shekhar Jadhav, Philip E. Johnson, Christopher P. Jones, Deepak Koirala, Emil L. Kristoffersen, Eric Largy, Anna Lewicka, Cameron D. Mackereth, Marco Marcia, Michela Nigro, Manju Ojha, Joseph A. Piccirilli, Phoebe A. Rice, Heewhan Shin, Anna‐Lena Steckelberg, Zhaoming Su, Yoshita Srivastava, Liu Wang, Yuan Wu, Jiahao Xie, Nikolaj H. Zwergius, John Moult, Andriy Kryshtafovych   +32 more
wiley   +1 more source