Results 31 to 40 of about 1,285,254 (263)

Serine Metabolism in Health and Disease and as a Conditionally Essential Amino Acid. [PDF]

Nutrients, 2022
L-serine plays an essential role in a broad range of cellular functions including protein synthesis, neurotransmission, and folate and methionine cycles and synthesis of sphingolipids, phospholipids, and sulphur containing amino acids.
Holeček M.
europepmc   +2 more sources

Hsa_circ_0062682 Promotes Serine Metabolism and Tumor Growth in Colorectal Cancer by Regulating the miR-940/PHGDH Axis

Frontiers in Cell and Developmental Biology, 2021
Colorectal cancer (CRC) is one of the most common malignancies globally. Increasing evidence indicates that circular RNAs (circRNAs) play a pivotal role in various cancers. The present study focused on exploring the role of a functionally unknown circRNA,
Shengbai Sun, Shengbai Sun, Chaoqun Li, Chaoqun Li, Kaisa Cui, Kaisa Cui, Bingxin Liu, Bingxin Liu, Mingyue Zhou, Mingyue Zhou, Yulin Cao, Yulin Cao, Jia Zhang, Jia Zhang, Zehua Bian, Zehua Bian, Bojian Fei, Zhaohui Huang, Zhaohui Huang   +18 more
doaj   +1 more source

Dietary intake and glutamine-serine metabolism control pathologic vascular stiffness [PDF]

Cell Metabolism
Thomas Bertero, Jingsi Zhao
exaly   +2 more sources

Serine biosynthesis with one carbon catabolism represents a novel pathway for ATP generation in cells using alternative glycolysis with zero net ATP production [PDF]

, 2011
Recent experimental evidence indicates that some cancer cells have an alternative glycolysis pathway with net zero ATP production, implying that upregulation of glycolysis in these cells may not be related to the generation of ATP.
Alexei Vazquez, Zoltan Oltvai, Zoltan N. Oltvai   +2 more
core   +3 more sources

The Dynamics of Metabolic Characterization in iPSC-Derived Kidney Organoid Differentiation via a Comparative Omics Approach

Frontiers in Genetics, 2021
The use of differentiating human induced pluripotent stem cells (hiPSCs) in mini-tissue organoids provides an invaluable resource for regenerative medicine applications, particularly in the field of disease modeling.
Qizheng Wang, Yucui Xiong, Yucui Xiong, Sheng Zhang, Sheng Zhang, Yufei Sui, Cunlai Yu, Peng Liu, Heying Li, Wenjing Guo, Yubo Gao, Aneta Przepiorski, Alan J. Davidson, Meijin Guo, Xiao Zhang, Xiao Zhang   +15 more
doaj   +1 more source

Insulin-regulated serine and lipid metabolism drive peripheral neuropathy [PDF]

, 2023
Diabetes represents a spectrum of disease in which metabolic dysfunction damages multiple organ systems including liver, kidneys and peripheral nerves(1,2).
Gengatharan, Jivani M., Green, Courtney R., Calcutt, Nigel A., Gantner, Marin L., Frizzi, Katie E, McGregor, Grace H., Moreno, Ana M, Ideguchi, Yoichiro, Wallace, Martina, Knight, Rob, Fallon, Regis J, Gantner, Marin L, Frizzi, Katie E., Mali, Prashant, Metallo, Christian M., Gengatharan, Jivani M, Rahman, Gibraan, Guernsey, Lucie S., Calcutt, Nigel A, Metallo, Christian M, Lin, Terry, Fallon, Regis J., Handzlik, Michal K., Moreno, Ana M., Panda, Satchidananda, Martino, Cameron, Tseng, Patrick, Handzlik, Michal K, Green, Courtney R, Gonzalez, Antonio, Chaix, Amandine, Guernsey, Lucie S, McGregor, Grace H, Antonio Gonzalez, Satchidananda Panda, Courtney R. Green, Marin L. Gantner, Katie E. Frizzi, Lucie S. Guernsey, Amandine Chaix, Prashant Mali, Patrick Tseng, Terry Lin, Christian M. Metallo, Michal K. Handzlik, Cameron Martino, Nigel A. Calcutt, Jivani M. Gengatharan, Martina Wallace, Grace H. McGregor, Rob Knight, Ana M. Moreno, Yoichiro Ideguchi, Gibraan Rahman, Regis J. Fallon   +54 more
core   +1 more source

Linking Serine/Glycine Metabolism to Radiotherapy Resistance [PDF]

Cancers, 2021
The activation of de novo serine/glycine biosynthesis in a subset of tumors has been described as a major contributor to tumor pathogenesis, poor outcome, and treatment resistance. Amplifications and mutations of de novo serine/glycine biosynthesis enzymes can trigger pathway activation; however, a large group of cancers displays serine/glycine pathway
Sanchez-Castillo, Anais, Vooijs, Marc, Kampen, Kim R.   +2 more
openaire   +4 more sources

Serine Supports IL-1β Production in Macrophages Through mTOR Signaling

Frontiers in Immunology, 2020
Intracellular metabolic programs tightly regulate the functions of macrophages, and previous studies have shown that serine mainly shapes the macrophage function via one-carbon metabolism.
Siyuan Chen, Yaoyao Xia, Fang He, Jian Fu, Zhongquan Xin, Baichuan Deng, Liuqin He, Xihong Zhou, Wenkai Ren   +8 more
doaj   +1 more source

glycine, serine & threonine metabolism-html

, 2014
unigenes associated with glycine, serine & threonine ...
Karen Fugate (480954)
core   +1 more source

glycine, serine & threonine metabolism-png

, 2014
unigenes associated with glycine, serine & threonine ...
Karen Fugate (480954)
core   +1 more source