Results 1 to 10 of about 374,590 (196)
Plasma Serotonin and Cardiovascular Outcomes in Chronic Kidney Disease
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023 Background Platelet‐poor plasma serotonin levels are associated with adverse cardiovascular outcomes. Although plasma serotonin levels increase in chronic kidney disease, the cardiovascular implications remain unknown.
Daniel Edmonston +2 more
doaj +2 more sources
The Effects of Serotonin in Immune Cells
Frontiers in Cardiovascular Medicine, 2017 Serotonin [5-hydroxytryptamine (5-HT)] plays an important role in many organs as a peripheral hormone. Most of the body’s serotonin is circulating in the bloodstream, transported by blood platelets and is released upon activation.
Nadine Herr +2 more
doaj +2 more sources
Psychiatric and cognitive function in patients with serotonin producing neuroendocrine tumors [PDF]
Translational PsychiatryCognitive and psychiatric problems are common in cancer patients, but literature on patients with neuroendocrine tumors (NET) is scarce. In a subset of these patients, the tumor produces serotonin, causing physical symptoms known as carcinoid syndrome ...
Maryse J. Luijendijk +12 more
doaj +2 more sources
Serotonin syndrome: a clinical review of current controversies [PDF]
Journal of Integrative Neuroscience, 2020 Serotonin syndrome is a state of increased central and peripheral serotonin (5-hydroxytryptamine) activity. Unless recognized and treated early, serotonin syndrome can lead to seizures, shock and death.
Ursula Werneke +3 more
doaj +1 more source
The serotonin theory of depression: a systematic umbrella review of the evidence
Molecular Psychiatry, 2022 The serotonin hypothesis of depression is still influential. We aimed to synthesise and evaluate evidence on whether depression is associated with lowered serotonin concentration or activity in a systematic umbrella review of the principal relevant areas
J. Moncrieff +5 more
semanticscholar +1 more source
International Journal of Molecular Sciences, 2022 Depression is a common and serious disorder, characterized by symptoms like anhedonia, lack of energy, sad mood, low appetite, and sleep disturbances.
A. Correia, N. Vale
semanticscholar +1 more source
The Role of Serotonin Neurotransmission in Gastrointestinal Tract and Pharmacotherapy
Molecules, 2022 5-Hydroxytryptamine (5-HT, serotonin) is a neurotransmitter in both the central nervous system and peripheral structures, acting also as a hormone in platelets.
Tomasz Guzel, D. Mirowska-Guzel
semanticscholar +1 more source
A genetically encoded sensor for measuring serotonin dynamics
Nature Neuroscience, 2021 Serotonin (5-HT) is a phylogenetically conserved monoamine neurotransmitter modulating important processes in the brain. To directly visualize the release of 5-HT, we developed a genetically encoded G-protein-coupled receptor (GPCR)-activation-based 5-HT
Jinxia Wan +18 more
semanticscholar +1 more source
Targeting SERT promotes tryptophan metabolism: mechanisms and implications in colon cancer treatment
Journal of Experimental & Clinical Cancer Research, 2021 Background Serotonin signaling has been associated with tumorigenesis and tumor progression. Targeting the serotonin transporter to block serotonin cellular uptake confers antineoplastic effects in various tumors, including colon cancer.
Di Ye +5 more
doaj +1 more source
Biomolecules, 2023 Serotonin effects on cardiac hypertrophy, senescence, and failure are dependent either on activation of specific receptors or serotonin uptake and serotonin degradation by monoamine oxidases (MAOs).
Jonas Knittel +6 more
doaj +1 more source