Results 91 to 100 of about 595,872 (286)

Effects of methamphetamine abuse and serotonin transporter gene variants on aggression and emotion-processing neurocircuitry. [PDF]

, 2012
Individuals who abuse methamphetamine (MA) exhibit heightened aggression, but the neurobiological underpinnings are poorly understood. As variability in the serotonin transporter (SERT) gene can influence aggression, this study assessed possible ...
London, ED, McCracken, JT, Nurmi, EL, Payer, DE, Wilson, SA   +4 more
core   +3 more sources

5-HT_FAsTR: a versatile, label-free, high-throughput, fluorescence-based microplate assay to quantify serotonin transport and release

Scientific Reports
The neurotransmitter serotonin plays a pivotal role in mood and depression. It also acts as a vasoconstrictor within blood vessels and is the main neurotransmitter in the gastrointestinal system.
Lina Bukowski, Markus Emanuel Strøm, Jens Lindengren Andersen, Jannick Bang Maesen, Lin Tian, Steffen Sinning   +5 more
doaj   +1 more source

Serotonin

Periodicum biologorum, 2011
Serotonin is a monoamine that could be found in plans, animals and human body. The homeostasis of serotonin is maintained by the series of interdependent processes that include synthesis, storage, transport and removal/degradation. In the human body serotonin is synthesized in two independent compartments that are separated by brain-blood barrier.
Muck-Šeler, Dorotea, Pivac, Nela
openaire   +4 more sources

Smoking-induced long-lasting modifications of human platelet serotonin catabolism through a MAO epigenetic regulation [PDF]

, 2008
Postulating that serotonin, secreted from smoking-activated platelets, could be involved in smoking-induced vascular modifications, we studied 115 men distributed in smokers (S), former smokers (FS) and never smokers (NS).
Alain Simon, Francine Rendu, Gilles Chironi, Jacques Callebert, Jacques Mallet, Jean-Louis Mé, Jean-Marie Launay, Katell Peoc', Muriel Del Pino   +8 more
core   +1 more source

Coordination of opposing sex-specific and core muscle groups regulates male tail posture during Caenorhabditis elegans male mating behavior [PDF]

, 2009
Background To survive and reproduce, animals must be able to modify their motor behavior in response to changes in the environment. We studied a complex behavior of Caenorhabditis elegans, male mating behavior, which provided a model for understanding ...
A Barrios, A Jones, A Jones, AA Beg, Allyson J Whittaker, BA Bamber, BB Wang, BJ Dickinson, C Loer, C Trent, D Weinshenker, DM Raizen, E Culetto, EM Gabriel, G Schindelman, H Ogawa, I Bany, I Putrenko, J Lewis, J Rand, J Richmond, J Srinivasan, J Sulston, J Sze, J White, JQ White, JT Fleming, K Liu, L Carnell, L Garcia, LE Waggoner, M Zhang, MM Francis, O Saifee, P Towers, Paul W Sternberg, RE Ritzmann, S Brenner, S Clark, SH Chalasani, SL McIntire, T Liu, W Schafer, Y Jin, Y Jin, Y Liu   +45 more
core   +4 more sources

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6, CYP2C19, CYP2B6, SLC6A4, and HTR2A Genotypes and Serotonin Reuptake Inhibitor Antidepressants

Clinical pharmacology and therapy, 2023
C. Bousman, J. Stevenson, L. Ramsey, K. Sangkuhl, J. K. Hicks, J. Strawn, Ajeet B. Singh, G. Ruaño, D. J. Mueller, Evangelia Eirini Tsermpini, Jacob T Brown, G. Bell, J. Leeder, A. Gaedigk, Stuart A. Scott, T. Klein, K. Caudle, J. Bishop   +17 more
semanticscholar   +1 more source

Platelet Serotonin Aggravates Myocardial Ischemia/Reperfusion Injury via Neutrophil Degranulation

Circulation, 2019
Background: Platelets store large amounts of serotonin that they release during thrombus formation or acute inflammation. This facilitates hemostasis and modulates the inflammatory response.
Maximilian Mauler, N. Herr, C. Schoenichen, T. Witsch, T. Marchini, C. Härdtner, C. Koentges, Korbinian Kienle, V. Ollivier, Maximilian Schell, Ludwig Dorner, Christopher Wippel, D. Stallmann, C. Normann, H. Bugger, P. Walther, D. Wolf, I. Ahrens, T. Lämmermann, B. Ho-Tin-Noé, K. Ley, C. Bode, I. Hilgendorf, D. Duerschmied   +23 more
semanticscholar   +1 more source

Preclinical discovery of duloxetine for the treatment of depression [PDF]

, 2012
Introduction: Affective disorders, including major depressive disorder (MDD), are among the most severely disabling mental disorders, and in many cases areIntroduction: Affective disorders, including major depressive disorder (MDD), are among the most ...
Berrocoso Domínguez, Esther María, Elorza, Julián, Micó Segura, Juan Antonio, Perez-Caballero, Laura, Torres-Sanchez, Sonia   +4 more
core   +2 more sources

Pharmacology of novel psychoactive substances [PDF]

, 2016
This PhD work consists of an in vitro and in vivo part. In the in vivo part, we investigated the role of dopamine in the acute clinical effects of 3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”) in healthy human subjects.
Rickli, Anna
core   +1 more source

An Association of Serotonin with Pain Disorders and Its Modulation by Estrogens

International Journal of Molecular Sciences, 2019
Ovarian hormones play an important role in pain perception, and are responsible, at least in part, for the pain threshold differences between the sexes.
S. Paredes, Santiago Cantillo, K. Candido, N. Knezevic   +3 more
semanticscholar   +1 more source