Results 111 to 120 of about 234,379 (321)
Serotonin receptors are involved in pathophysiology of schizophrenia and may mediate other neurotransmitter effects. We investigated serotonin receptors gene expression in peripheral blood mononuclear cells (PBMC) of naïve schizophrenic patients, before
Gholam Reza Shariati+5 more
doaj
Background Melatonin and serotonin are well-known signaling molecules that mediate multiple physiological activities in plants, including stress defense, growth, development, and morphogenesis, but their underlying mechanisms have not yet been thoroughly
Jinpeng Wan+5 more
doaj +1 more source
Objective Systemic sclerosis (SSc) is a connective tissue disease with fibrotic remodeling of the skin and various internal organs. SSc is associated with the highest case‐specific mortality of all rheumatic autoimmune diseases with limited antifibrotic treatment options.
Thuong Trinh‐Minh+12 more
wiley +1 more source
Contemporary management of pain in cirrhosis: Toward precision therapy for pain
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman+4 more
wiley +1 more source
Neuromodulated Patience for Robot and Self-Driving Vehicle Navigation [PDF]
Robots and self-driving vehicles face a number of challenges when navigating through real environments. Successful navigation in dynamic environments requires prioritizing subtasks and monitoring resources. Animals are under similar constraints. It has been shown that the neuromodulator serotonin regulates impulsiveness and patience in animals.
arxiv
Studies with the Serotonin Precursor, 5-Hydroxytryptophan, in Experimental Animals and Man [PDF]
John D. Davidson+3 more
openalex +1 more source
This study compared the clinical effectiveness and treatment satisfaction of Pregabalin and Gabapentin triple therapy for neuropathic pain in a real‐world setting. The primary outcome measured the reduction in mean Self‐Administered Leeds Assessment of Neuropathic Symptoms and Signs pain score value from baseline to 12 weeks posttreatment.
Nithya Raju+7 more
wiley +1 more source
Mechanisms underlying the response of mouse cortical networks to optogenetic manipulation [PDF]
GABAergic interneurons can be subdivided into three subclasses: parvalbumin positive (PV), somatostatin positive (SOM) and serotonin positive neurons. With principal cells (PCs) they form complex networks. We examine PCs and PV responses in mouse anterior lateral motor cortex (ALM) and barrel cortex (S1) upon PV photostimulation in vivo.
arxiv
Effects of Serotonin Antagonists in Normal Subjects and Patients with Carcinoid Tumors [PDF]
Roland E. Schneckloth+3 more
openalex +1 more source
Aim This study builds on the environmental risk analysis presented in the 2022 National Report on Medicines Use in Italy by the Italian Medicines Agency and aims to assess the environmental risk posed by medicines in Italy and its regions. Methods The analysis selected 90 medicines based on three criteria: high utilization, low predicted no effect ...
Valentina Giunchi+8 more
wiley +1 more source