Results 111 to 120 of about 595,872 (286)

Seasonal variation of serotonin turnover in human cerebrospinal fluid, depressive symptoms and the role of the 5-HTTLPR. [PDF]

open access: yes, 2013
Studying monoaminergic seasonality is likely to improve our understanding of neurobiological mechanisms underlying season-associated physiological and pathophysiological behavior.
Bakker, SC   +16 more
core   +2 more sources

Activity patterns of serotonin neurons underlying cognitive flexibility

open access: yeseLife, 2017
Serotonin is implicated in mood and affective disorders. However, growing evidence suggests that a core endogenous role is to promote flexible adaptation to changes in the causal structure of the environment, through behavioral inhibition and enhanced ...
Sara Matias   +3 more
semanticscholar   +1 more source

Melatonin Natural Health Products and Supplements: Presence of Serotonin and Significant Variability of Melatonin Content.

open access: yesJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2017
STUDY OBJECTIVES Melatonin is an important neurohormone, which mediates circadian rhythms and the sleep cycle. As such, it is a popular and readily available supplement for the treatment and prevention of sleep-related disorders including insomnia and ...
Lauren A. E. Erland, P. Saxena
semanticscholar   +1 more source

Serotonin drives a novel GABAergic synaptic current recorded in rat cerebellar purkinje cells: a lugaro cell to Purkinje cell synapse [PDF]

open access: yes, 2003
We recorded a novel fast GABAergic synaptic current in cerebellar Purkinje cells in rat brain slices using patch-clamp techniques. Because of a relatively low sensitivity to bicuculline, these currents can be recorded under conditions in which basket ...
Dean, I., Edwards, F.A., Robertson, S.J.
core  

Understanding vulnerability for depression from a cognitive neuroscience perspective: a reappraisal of attentional factors and a new conceptual framework [PDF]

open access: yes, 2010
We propose a framework to understand increases in vulnerability for depression after recurrent episodes that links attention processes and schema activation to negative mood states, by integrating cognitive and neurobiological findings.
De Raedt, Rudi, Koster, Ernst
core   +1 more source

Endophenotypes and serotonergic polymorphisms associated with treatment response in obsessive-compulsive disorder

open access: yesClinics, 2012
OBJECTIVES: Approximately 40-60% of obsessive-compulsive disorder patients are nonresponsive to serotonin reuptake inhibitors. Genetic markers associated with treatment response remain largely unknown.
Fábio M. Corregiari   +3 more
doaj   +1 more source

Serotonin signals through a gut-liver axis to regulate hepatic steatosis

open access: yesNature Communications, 2018
Nonalcoholic fatty liver disease (NAFLD) is increasing in worldwide prevalence, closely tracking the obesity epidemic, but specific pharmaceutical treatments for NAFLD are lacking.
Wonsuk Choi   +19 more
semanticscholar   +1 more source

Comparative physiological responses and transcriptome analysis reveal the roles of melatonin and serotonin in regulating growth and metabolism in Arabidopsis

open access: yesBMC Plant Biology, 2018
Background Melatonin and serotonin are well-known signaling molecules that mediate multiple physiological activities in plants, including stress defense, growth, development, and morphogenesis, but their underlying mechanisms have not yet been thoroughly
Jinpeng Wan   +5 more
doaj   +1 more source

Antibiotics-induced depletion of mice microbiota induces changes in host serotonin biosynthesis and intestinal motility

open access: yesJournal of Translational Medicine, 2017
BackgroundThe gastrointestinal motility is affected by gut microbiota and the relationship between them has become a hot topic. However, mechanisms of microbiota in regulating motility have not been well defined.
X. Ge   +8 more
semanticscholar   +1 more source

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