Results 11 to 20 of about 595,872 (286)
Serotonin Syndrome/Serotonin Toxicity [PDF]
Federal Practitioner, 2020 This review of serotonin syndrome or serotonin toxicity covers the years 2014 to 2019, including information on pathophysiology, etiology, and diagnosis, 3 criteria for diagnosing serotonin syndrome, and criteria for neuroleptic malignant syndrome.The review highlights the potential lethal combinations of commonly prescribed medications used to treat ...
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DNA methylation of the serotonin transporter gene in peripheral cells and stress-related changes in hippocampal volume: a study in depressed patients and healthy controls. [PDF]
PLoS ONE, 2015 Serotonin plays an important role in the etiology of depression. Serotonin is also crucial for brain development. For instance, animal studies have demonstrated that early disruptions in the serotonin system affect brain development and emotion ...
Linda Booij +11 more
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Illumination of serotonin transporter mechanism and role of the allosteric site
Science Advances, 2021 Cryo-EM and binding experiments reveal the molecular mechanism of serotonin transport by the human serotonin transporter.
Dongxue Yang, E. Gouaux
semanticscholar +1 more source
Serotonin and schizophrenia [PDF]
, 2010 Abstract Although the serotonin hypothesis of schizophrenia is one of the oldest neurochemical hypotheses on the pathogenesis of the disease, it is still topical. The concept of how the serotonin system is involved in the origin and progress of schizophrenia has changed considerably over the past decades.
Quednow, Boris B +2 more
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Role of serotonin receptor signaling in cancer cells and anti-tumor immunity
Theranostics, 2021 Serotonin or 5-hydroxytryptamine (5-HT) is a neurotransmitter known to affect emotion, behavior, and cognition, and its effects are mostly studied in neurological diseases.
Surojit Karmakar, G. Lal
semanticscholar +1 more source
Neuropsychopharmacology, 1999 Forty-five years after its discovery, brain serotonin (5-HT) is still the subject of intense research aimed at understanding its role in stress adaptation. At the presynaptic level, numerous stressors increase nerve firing and extracellular 5-HT at the level of serotonergic cell bodies or nerve terminals.
Chaouloff, F. +2 more
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Frontiers in Molecular Neuroscience, 2020 A number of studies implicate biogenic amines in regulating circadian rhythms. In particular, dopamine and serotonin influence the entrainment of circadian rhythms to daily food availability.
Christian M. Gallardo +2 more
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Increased release of serotonin from rat primary isolated adult cardiac myofibroblasts
Scientific Reports, 2021 Elevated blood serotonin levels have been observed in patients with heart failure and serotonin has a role in pathological cardiac function. The serotonin receptor system was examined in adult rat isolated cardiac fibroblast and myofibroblast cells. This
Emiri Tarbit +4 more
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Frontiers in Microbiology, 2022 Herpes simplex virus-associated diseases are a complex interaction between cytolytic viral replication and inflammation. Within the normally avascular and immunoprivileged cornea, HSV ocular infection can result in vision-threatening immune-mediated ...
Diana Marie Battaglia +8 more
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International Journal of Molecular Sciences, 2021 Serotonin (5-hydroxytryptamine, 5-HT) is a biogenic monoamine produced from the essential amino acid tryptophan. Serotonin’s role as a neurotransmitter in the central nervous system and a motility mediator in the gastrointestinal tract has been well ...
Pragathi Balakrishna +3 more
semanticscholar +1 more source