Results 21 to 30 of about 234,379 (321)

Telotristat ethyl reverses myxomatous changes in mice mitral valves

open access: yesFrontiers in Cardiovascular Medicine, 2022
RationaleMyxomatous mitral valve degeneration is a common pathological manifestation of mitral valve regurgitation, with or without valvular prolapse.
Xinmei Wang   +3 more
doaj   +1 more source

Glassy Carbon Microelectrode Arrays Enable Voltage-Peak Separated Simultaneous Detection of Dopamine and Serotonin Using Fast Scan Cyclic Voltammetry [PDF]

open access: yes, 2020
Progress in real-time, simultaneous in vivo detection of multiple neurotransmitters will help accelerate advances in neuroscience research. The need for development of probes capable of stable electrochemical detection of rapid neurotransmitter fluctuations with high sensitivity and selectivity and sub-second temporal resolution has, therefore, become ...
arxiv   +1 more source

Serotonin transporter dependent modulation of food-seeking behavior.

open access: yesPLoS ONE, 2020
The olfactory pathway integrates the odor information required to generate correct behavioral responses. To address how changes of serotonin signaling in two contralaterally projecting, serotonin-immunoreactive deutocerebral neurons impacts key odorant ...
Jianzheng He   +4 more
doaj   +1 more source

Serotonin signaling regulates actomyosin contractility during morphogenesis in evolutionarily divergent lineages

open access: yesNature Communications, 2023
Serotonin is a neurotransmitter that signals through 5-HT receptors to control key functions in the nervous system. Serotonin receptors are also ubiquitously expressed in various organs and have been detected in embryos of different organisms.
Sanjay Karki   +7 more
doaj   +1 more source

Serotonin and Hallucinogens [PDF]

open access: yesNeuropsychopharmacology, 1999
This brief review traces the serotonin (5-HT) hypothesis of the action of hallucinogenic drugs from the early 1950s to the present day. There is now converging evidence from biochemical, electrophysiological, and behavioral studies that the two major classes of psychedelic hallucinogens, the indoleamines (e.g., LSD) and the phenethylamines (e.g ...
Gerard J. Marek, George K. Aghajanian
openaire   +3 more sources

Identification, functional characterization and pharmacological profile of a serotonin type-2b receptor in the medically important insect, Rhodnius prolixus

open access: yesFrontiers in Neuroscience, 2015
In the Chagas disease vector, Rhodnius prolixus, two diuretic hormones act synergistically to dramatically increase fluid secretion by the Malpighian tubules (MTs) during the rapid diuresis that is initiated upon engorgement of vertebrate blood.
Jean-Paul V Paluzzi   +10 more
doaj   +1 more source

Arresting serotonin [PDF]

open access: yesProceedings of the National Academy of Sciences, 2008
[No abstract available]
Bryan L. Roth, Atheir I. Abbas
openaire   +3 more sources

Structure‐guided identification of a selective sulfonamide‐based inhibitor targeting the human carbonic anhydrase VA isoform

open access: yesArchiv der Pharmazie, Volume 356, Issue 1, January 2023., 2023
Combining ligand‐based and structure‐based methodologies, the applied virtual screening approach identified a collection of sulfonamides targeting the human carbonic anhydrase (hCA) VA isoform. 2‐(3,4‐Dihydro‐2H‐quinolin‐1‐yl)‐N‐(4‐sulfamoylphenyl)acetamide was identified as a potent and selective lead compound as a candidate for further exploitation ...
Laura De Luca   +4 more
wiley   +1 more source

Linear Latent Variable Models: The lava-package [PDF]

open access: yesComputational Statistics, Volume 28, Issue 4 , pp 1385-1452, 2012
An R package for specifying and estimating linear latent variable models is presented. The philosophy of the implementation is to separate the model specification from the actual data, which leads to a dynamic and easy way of modeling complex hierarchical structures.
arxiv   +1 more source

Interaction between Intestinal Microbiota and Serotonin Metabolism

open access: yesJournal of Mazandaran University of Medical Sciences, 2021
Gut microbiota regulates the production of signaling molecules, such as serotonin or 5-Hydroxytryptamine: 5-HT in the host. Serotonin is a biogenic amine that acts as a neurotransmitter in the gut and brain.
Rezvan Yaghobfar   +5 more
doaj  

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