Results 111 to 120 of about 40,842 (165)
Some of the next articles are maybe not open access.
Serotonin Antagonists as Antipsychotics
1993Recent evidence has indicated that antagonism of serotonin receptor subtypes may, in part, be responsible for the atypical profile of some antipsychotic drugs. In the past, our lab has investigated the neurobiology of the tridecapeptide neurotransmitter neurotensin (NT).
Becky L. Kinkead +2 more
openaire +1 more source
Psychotherapeutics and Serotonin Agonists and Antagonists
Journal of Clinical Gastroenterology, 2005Treatment of irritable bowel syndrome (IBS) remains challenging for patients and practitioners. Current therapeutic choices include antidepressants and psychotherapy, which are thought to target central nervous system triggers of symptoms. Data supporting these treatments are reviewed.
openaire +2 more sources
Treatment of "Dumping with Serotonin Antagonists
JAMA, 1962RECENT STUDIES in our laboratories have shown that a circulating agent of intestinal origin may be responsible for initiating the early symptomatic phase of the postgastrectomy dumping syndrome. Since serotonin and related substances have pharmacologie actions compatible with the physiologic derangements seen in dumping, and are released from the upper
L P, JOHNSON, R D, SLOOP, J E, JESSEPH
openaire +2 more sources
Serotonin Agonists and Antagonists in Experimental Hypertension
Journal of Cardiovascular Pharmacology, 1987Serotonin (5-hydroxytryptamine; also called 5-HT) modifies cardiovascular activity by central as well as peripheral sites of action. When 5-HT is injected within the central nervous system, depending upon the dose and site of administration, either a pressor or a depressor effect is observed.
P R, Saxena, G R, Bolt, K M, Dhasmana
openaire +2 more sources
O-Methylasparvenone, a nitrogen-free serotonin antagonist
Bioorganic & Medicinal Chemistry, 1997O-Methylasparvenone (1) and asparvenone (2) were isolated from an Aspergillus parvulus Smith broth in a microbial screening for 5-HT2C ligands and found to be 5-HT2C antagonists. They represent the first nitrogen-free serotonin ligands. The absolute configuration of 1 was determined to be S by X-ray analysis of the corresponding Mosher-ester.
M, Bös +5 more
openaire +2 more sources
Influence of serotonin antagonists on bulbospinal systems
Brain Research, 1973Abstract We attempted to elucidate the function of the serotonin-containing bulbospinal neurons by directly stimulating the raphe nucleus of unanesthetized decerebrates cats. Such stimuli evoked both a dorsal and a ventral root potential, and produced a complex time-dependent facilitation and inhibition of segmentally evoked monosynaptic reflexes ...
H K, Proudfit, E G, Anderson
openaire +2 more sources
Serotonin, Serotonergic Antagonists, and Hypertension
1986Whether the increased total systemic vascular resistance characteristic of chronic hypertension is a primary event or secondary to increased cardiac output is still debated. Whatever the initiating cause, the increased resistance must result from the narrowing of the small arteries and arterioles (Fig. 1).
P. M. Vanhoutte, R. F. J. Shepherd
openaire +1 more source