Results 231 to 240 of about 235,344 (293)
Some of the next articles are maybe not open access.
Clozapine—A Serotonin Antagonist?
Pharmacology Biochemistry and Behavior, 1984The effect of clozapine on the central serotonergic transmission system was studied by investigation of open-field motility of rats after microinjection of drugs into nucleus accumbens and median raphe nucleus. Previous work has shown that LSD in low doses potentiates apomorphine-induced hypermotility and that this LSD effect is induced by a serotonin ...
R Morgenstern, H Fink, W Oelssner
exaly +3 more sources
Effects of serotonin and serotonin antagonists on chick embryogenesis
Wilhelm Roux's Archives of Developmental Biology, 1979Serotonin and some selected substances known to interfere with its formation (diethyldithiocarbamate) and function (Catron®, 5-methyltryptamine, promethazine) were tested for their ability to affect chick embryo morphogenesis during the first 48 h of development.
Kjell, Palén +2 more
openaire +2 more sources
Serotonin Antagonism and Serotonin Antagonists in Pregnancy: Role of Ketanserin
Obstetrical & Gynecological Survey, 2000Most agree that antihypertensive medication should be used to treat severe hypertension during pregnancy, but its role in patients with mild to moderate disease is debated. None of the regularly used drugs is completely safe for mother and fetus. Ketanserin decreases systolic and diastolic blood pressure in nonpregnant patients with acute and chronic ...
D W, Steyn, H J, Odendaal
openaire +2 more sources
Australian and New Zealand Journal of Medicine, 1984
The realisation that serotonin plays a role not only in the carcinoid syndrome but also in migraine, nociception, dumping syndrome, vascular disease and hypertension, has led to an enormous amount of activity in search of serotonin antagonists. Numerous such pharmacological agents have been identified but only few have found their way into clinical use.
openaire +2 more sources
The realisation that serotonin plays a role not only in the carcinoid syndrome but also in migraine, nociception, dumping syndrome, vascular disease and hypertension, has led to an enormous amount of activity in search of serotonin antagonists. Numerous such pharmacological agents have been identified but only few have found their way into clinical use.
openaire +2 more sources
Serotonin antagonists and vascular protection
Cardiovascular Drugs and Therapy, 1990There is very suggestive evidence for a role of serotonin release from platelets in the mechanisms for platelet aggregation, arterial thrombosis, and arterial spasm. These effects are mediated via the 5HT2 receptor and are specifically antagonized by ketanserin.
openaire +2 more sources
Psychotherapeutics and Serotonin Agonists and Antagonists
Journal of Clinical Gastroenterology, 2005Treatment of irritable bowel syndrome (IBS) remains challenging for patients and practitioners. Current therapeutic choices include antidepressants and psychotherapy, which are thought to target central nervous system triggers of symptoms. Data supporting these treatments are reviewed.
openaire +2 more sources
Cinnamamides as structural analogs and antagonists of serotonin
Biochemical Pharmacology, 1964Abstract Cinnamamides with aminoalkyl groups on the amide nitrogen were conceived as structural analogs of serotonin which would act as antimetabolites of it. Several such amides were synthesized and tested for antiserotonin activity on the isolated rat uterus and in living animal. All such amides that were tested acted as antagonists of the hormone.
R S, DOMBRO, D W, WOOLLEY
openaire +2 more sources