Serotonin antagonists - Open Access .click

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The effect of serotonin and serotonin antagonists on external pancreatic secretion in dogs

Journal of Surgical Research, 1963
Summary Suppression of external pancreatic secretion in dogs was produced by exogenous serotonin (serotonin creatinine sulfate) despite constant secretin stimulation and despite vagotomy or atropine. Attempts to modify this response, and attempts to modify the similar response to intraduodenal hypertonic feedings, by pretreatment with a number of ...
J J, HUDOCK, A, KHENTIGAN, P, VANAMEE, W, LAWRENCE +3 more
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The Evolution of the Serotonin-Dopamine Antagonist Concept

Journal of Clinical Psychopharmacology, 1995
Before the dopamine hypothesis of schizophrenia became established, a serotonin (5-hydroxy-tryptamine) 5-HT hypothesis was popular. This was based on the hallucinogenic properties of lysergic acid diethlyamide and abnormal serotonin levels in schizophrenics. Suggestions that serotonin might be involved in the cause of schizophrenia or could be a target
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The Role of Serotonin in Schizophrenia and the Place of Serotonin-Dopamine Antagonist Antipsychotics

Journal of Clinical Psychopharmacology, 1995
After four decades of the use of antipsychotic drugs that target the dopamine D2 receptor as the initial site of action, a new strategy for antipsychotic therapy has emerged and, with it, new hope for greater efficacy and fewer side effects. This new strategy involves identifying drugs with strong serotonin (5-hydroxytryptamine) 5-HT2A receptor ...
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Ketanserin, A Serotonin Antagonist