Results 251 to 260 of about 77,943 (311)
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Effects of serotonin and serotonin antagonists on chick embryogenesis
Wilhelm Roux's Archives of Developmental Biology, 1979Serotonin and some selected substances known to interfere with its formation (diethyldithiocarbamate) and function (Catron®, 5-methyltryptamine, promethazine) were tested for their ability to affect chick embryo morphogenesis during the first 48 h of development.
Kjell, Palén +2 more
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Australian and New Zealand Journal of Medicine, 1984
The realisation that serotonin plays a role not only in the carcinoid syndrome but also in migraine, nociception, dumping syndrome, vascular disease and hypertension, has led to an enormous amount of activity in search of serotonin antagonists. Numerous such pharmacological agents have been identified but only few have found their way into clinical use.
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The realisation that serotonin plays a role not only in the carcinoid syndrome but also in migraine, nociception, dumping syndrome, vascular disease and hypertension, has led to an enormous amount of activity in search of serotonin antagonists. Numerous such pharmacological agents have been identified but only few have found their way into clinical use.
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Serotonin antagonists and vascular protection
Cardiovascular Drugs and Therapy, 1990There is very suggestive evidence for a role of serotonin release from platelets in the mechanisms for platelet aggregation, arterial thrombosis, and arterial spasm. These effects are mediated via the 5HT2 receptor and are specifically antagonized by ketanserin.
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Granisetron: The Second Serotonin-Receptor Antagonist
Annals of Pharmacotherapy, 1995Objective: To review the pharmacology, pharmacokinetics, clinical efficacy, and adverse effects of granisetron, focusing on critical analysis of published clinical trials and comparison with other antiemetic agents, including ondansetron. Data Sources: MEDLINE (1966–1995) and CANCERLIT (1991–1995) searches of English-language literature using the terms
V R, Adams, A W, Valley
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Hyperglycemic properties of serotonin receptor antagonists
Life Sciences, 1991Several serotonin (5-HT) receptor antagonists with varying specificities for the 5-HT receptor types, were studied with regard to their effects on blood glucose levels in mice. The non-selective antagonists, metergoline and methysergide, proved to be hyperglycemic at doses commonly used to antagonize 5-HT receptors. In contrast, ritanserin (a 5-HT2 and
K M, Wozniak, M, Linnoila
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Serotonin Antagonism and Serotonin Antagonists in Pregnancy: Role of Ketanserin
Obstetrical & Gynecological Survey, 2000Most agree that antihypertensive medication should be used to treat severe hypertension during pregnancy, but its role in patients with mild to moderate disease is debated. None of the regularly used drugs is completely safe for mother and fetus. Ketanserin decreases systolic and diastolic blood pressure in nonpregnant patients with acute and chronic ...
D W, Steyn, H J, Odendaal
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Serotonin Antagonists as Antipsychotics
1993Recent evidence has indicated that antagonism of serotonin receptor subtypes may, in part, be responsible for the atypical profile of some antipsychotic drugs. In the past, our lab has investigated the neurobiology of the tridecapeptide neurotransmitter neurotensin (NT).
Becky L. Kinkead +2 more
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Psychotherapeutics and Serotonin Agonists and Antagonists
Journal of Clinical Gastroenterology, 2005Treatment of irritable bowel syndrome (IBS) remains challenging for patients and practitioners. Current therapeutic choices include antidepressants and psychotherapy, which are thought to target central nervous system triggers of symptoms. Data supporting these treatments are reviewed.
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Treatment of "Dumping with Serotonin Antagonists
JAMA, 1962RECENT STUDIES in our laboratories have shown that a circulating agent of intestinal origin may be responsible for initiating the early symptomatic phase of the postgastrectomy dumping syndrome. Since serotonin and related substances have pharmacologie actions compatible with the physiologic derangements seen in dumping, and are released from the upper
L P, JOHNSON, R D, SLOOP, J E, JESSEPH
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Serotonin Agonists and Antagonists in Experimental Hypertension
Journal of Cardiovascular Pharmacology, 1987Serotonin (5-hydroxytryptamine; also called 5-HT) modifies cardiovascular activity by central as well as peripheral sites of action. When 5-HT is injected within the central nervous system, depending upon the dose and site of administration, either a pressor or a depressor effect is observed.
P R, Saxena, G R, Bolt, K M, Dhasmana
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