Results 91 to 100 of about 244,384 (312)
Oligonucleotide‐induced alternative splicing of serotonin 2C receptor reduces food intake
EMBO Molecular Medicine, 2016 The serotonin 2C receptor regulates food uptake, and its activity is regulated by alternative pre‐mRNA splicing. Alternative exon skipping is predicted to generate a truncated receptor protein isoform, whose existence was confirmed with a new antiserum ...
Zhaiyi Zhang +6 more
doaj +1 more source
Neuropharmacological classification of antidepressant agents based on their mechanisms of action
Archives of Medicine and Health Sciences, 2018 The currently available clinical antidepressants can be classified into 13 different classes based on their mechanisms of action. These basic pharmacological concepts thoroughly elucidate and unravel the therapeutic actions and side effects of the wide ...
Olumuyiwa John Fasipe
doaj +1 more source
2B Determined: The Future of the Serotonin Receptor 2B in Drug Discovery [PDF]
, 2023 Aaron M. Bender +4 more
openalex +1 more source
Integrating the inputs that shape pancreatic islet hormone release. [PDF]
, 2019 The pancreatic islet is a complex mini organ composed of a variety of endocrine cells and their support cells, which together tightly control blood glucose homeostasis.
Huising, Mark O, Noguchi, Glyn M
core
Understanding vulnerability for depression from a cognitive neuroscience perspective: a reappraisal of attentional factors and a new conceptual framework [PDF]
, 2010 We propose a framework to understand increases in vulnerability for depression after recurrent episodes that links attention processes and schema activation to negative mood states, by integrating cognitive and neurobiological findings.
De Raedt, Rudi, Koster, Ernst
core +1 more source
Advanced Science, EarlyView.Random ssDNA–SWCNT(single strand DNA‐single walled carbon nanotube) library is functionally screened and evolved using high‐throughput 3D prostate tumor spheroids via iterative positive and negative selection, enabling the identification of NIR‐II fluorescent ssDNA‐SWCNT nanoprobe specific for prostate cancer.
Dakyeon Lee +8 more
wiley +1 more source
Seasonal Affective Disorder and Serotonin-Related Polymorphisms
Neurobiology of Disease, 2001 Disturbances in central serotonergic systems have been hypothesized to be involved in seasonal affective disorder (SAD). Association between SAD and the shorter allele of the serotonin transporter promoter repeat length polymorphism (5-HTTLPR) has been ...
C. Johansson +10 more
doaj +1 more source
Triptans and CGRP blockade - impact on the cranial vasculature [PDF]
, 2017 The trigeminovascular system plays a key role in the pathophysiology of migraine. The activation of the trigeminovascular system causes release of various neurotransmitters and neuropeptides, including serotonin and calcitonin gene-related peptide ...
Alejandro Labastida-Ramírez +9 more
core +3 more sources
Hearing Loss: From Basic to Clinical Science
Advanced Science, EarlyView.Abstract Hearing loss (HL) affects over 1.5 billion people globally, with genetic factors accounting for ≈50% of congenital cases. Therefore, HL has become a global health issue, driving extensive research from basic science to clinical applications. This Special Collection includes a total of 31 papers, among which 9 are review papers, 21 are research
Renjie Chai, Hai Huang, Jing Zou
wiley +1 more source
Ibrain, EarlyView., 2023 This study compared the clinical effectiveness and treatment satisfaction of Pregabalin and Gabapentin triple therapy for neuropathic pain in a real‐world setting. The primary outcome measured the reduction in mean Self‐Administered Leeds Assessment of Neuropathic Symptoms and Signs pain score value from baseline to 12 weeks posttreatment.
Nithya Raju +7 more
wiley +1 more source