Results 21 to 30 of about 244,384 (312)

The effects of glycogen synthase kinase-3beta in serotonin neurons. [PDF]

open access: yesPLoS ONE, 2012
Glycogen synthase kinase-3 (GSK3) is a constitutively active protein kinase in brain. Increasing evidence has shown that GSK3 acts as a modulator in the serotonin neurotransmission system, including direct interaction with serotonin 1B (5-HT1B) receptors
Wenjun Zhou   +9 more
doaj   +1 more source

Serotonin and motherhood: From molecules to mood [PDF]

open access: yes, 2019
Emerging research points to a valuable role of the monoamine neurotransmitter, serotonin, in the display of maternal behaviors and reproduction-associated plasticity in the maternal brain.
Li, Ming   +2 more
core   +3 more sources

Endophenotypes and serotonergic polymorphisms associated with treatment response in obsessive-compulsive disorder

open access: yesClinics, 2012
OBJECTIVES: Approximately 40-60% of obsessive-compulsive disorder patients are nonresponsive to serotonin reuptake inhibitors. Genetic markers associated with treatment response remain largely unknown.
Fábio M. Corregiari   +3 more
doaj   +1 more source

Efficacy of serotonin receptor agonists in the treatment of functional dyspepsia: a meta-analysis

open access: yesArchives of Medical Science, 2018
Introduction Functional dyspepsia (FD) is typically treated with serotonin receptor (5-HT) agonists such as cisapride, mosapride, tegaserod and tandospirone citrate.
Man Jin   +5 more
doaj   +1 more source

Mice in ecstasy : advanced animal models in the study of MDMA [PDF]

open access: yes, 2010
The party drug 3,4-methylenedioxymethamphetamine -better known as MDMA or ecstasy- has numerous effects on the human body, characterized by a rush of energy, euphoria and empathy.
Stove, Christophe   +3 more
core   +2 more sources

Serotonin reuptake inhibitors and cardiovascular disease [PDF]

open access: yes, 2005
Selective serotonin re-uptake inhibiting drugs (SSRIs) are widely used for endogenous depression. In addition to depleting the nerve terminals of serotonin they also lower blood platelet serotonin levels.
Belcher, P.R.   +2 more
core   +1 more source

The Serotonin Receptor Subtype 5b Specifically Interacts with Serotonin Receptor Subtype 1A

open access: yesFrontiers in Molecular Neuroscience, 2017
Previously, we described the dysregulation of serotonin (5-HT) receptor subtype 5b (5-ht5b) in a mouse model of Rett syndrome (RTT). 5-ht5b has not been extensively studied, so we set out to characterize it in more detail.
Sabine Niebert   +7 more
doaj   +1 more source

Monoamine Oxidase A Contributes to Serotonin—But Not Norepinephrine-Dependent Damage of Rat Ventricular Myocytes

open access: yesBiomolecules, 2023
Serotonin effects on cardiac hypertrophy, senescence, and failure are dependent either on activation of specific receptors or serotonin uptake and serotonin degradation by monoamine oxidases (MAOs).
Jonas Knittel   +6 more
doaj   +1 more source

Serotonin system implication in L-DOPA-induced dyskinesia: from animal models to clinical investigations [PDF]

open access: yes, 2014
In the recent years, the serotonin system has emerged as a key player in the induction of l-DOPA-induced dyskinesia (LID) in animal models of Parkinson's disease. In fact, serotonin neurons possess the enzymatic machinery able to convert exogenous l-DOPA
CARTA, MANOLO, TRONCI, ELISABETTA
core   +1 more source

Signaling pathways linking behavior to neurogenesis in healthy brain and disease [PDF]

open access: yes, 2020
Self-repair of the adult brain is limited – most diseases lack effective therapy. In order to better understand how a regenerative response can be achieved, studying mechanisms shaping the neurogenic niche, from environmental factors to intrinsic ...
Klempin, Friederike
core   +1 more source

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