Results 131 to 140 of about 86,902 (236)

Effects of Electroacupuncture at ST36 on Visceral Pain and Inflammatory Markers in IBS Rats

open access: yesNeurogastroenterology &Motility, EarlyView.
Electroacupuncture (EA) at ST36 significantly reduced visceral pain and colonic inflammation in IBS model rats. EA increased pain thresholds, lowered AWR scores, and downregulated key inflammatory mediators (IL‐1β, IL‐6, TNF‐α, TRPV1, NF‐κB). These findings highlight ST36‐targeted EA as a promising therapeutic strategy for IBS visceral hypersensitivity
Ya‐bo Hao   +6 more
wiley   +1 more source

Functional and structural connectivity of thalamic subnuclei in major depressive disorder at 7 Tesla

open access: yesPsychiatry and Clinical Neurosciences, EarlyView.
Aims Major depressive disorder (MDD) is widely considered to be a mood disorder characterized by altered connectivity. The thalamus plays an important role in MDD by connecting large areas of the brain. Here, we explored thalamic connectivity in MDD at the subnuclear level using ultra‐high‐field MRI.
Weijian Liu   +10 more
wiley   +1 more source

Psychobiotics and the microbiota–gut–brain axis: Emerging paradigms in mental health modulation

open access: yesExperimental Physiology, EarlyView.
Abstract The global rise in mental health conditions has prompted interest in interventions that act beyond conventional psychopharmacology. Psychobiotics, broadly understood as live microorganisms or microbe‐derived products that interact with the microbiota–gut–brain axis, have been suggested to exert neuroactive effects through neural, immune ...
Amir Arsalan Ghahari   +4 more
wiley   +1 more source

Early adversity and the comorbidity between metabolic disease and psychopathology

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas   +1 more
wiley   +1 more source

Intramuscular pathways of maladaptation in overtraining syndrome

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The transition from adaptive overreaching to maladaptive overtraining and mechanisms through which excessive training load can lead to performance decline. Four interconnected pathophysiological domains are highlighted: neural fatigue, involving both central and peripheral components such as altered sensory feedback and reflex ...
Emily Shorter   +4 more
wiley   +1 more source

14‐3‐3 proteins: Regulators of cardiac excitation–contraction coupling and stress responses

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend 14‐3‐3 protein interactions in cardiac regulation. Schematic representation of 14‐3‐3 binding partners in excitation–contraction coupling, transcriptional regulation/development and stress response pathways. Asterisks indicate targets where the exact 14‐3‐3 binding site is unknown.
Heather C. Spooner, Rose E. Dixon
wiley   +1 more source

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