Results 91 to 100 of about 709,580 (281)

β-Amyloid(1-42)-Induced Cholinergic Lesions in Rat Nucleus Basalis Bidirectionally Modulate Serotonergic Innervation of the Basal Forebrain and Cerebral Cortex

Neurobiology of Disease, 2001
Ample experimental evidence suggests that β-amyloid (Aβ), when injected into the rat magnocellular nucleus basalis (MBN), impels excitotoxic injury of cholinergic projection neurons.
Tibor Harkany, Sheila O'Mahony, Jan Keijser, John P. Kelly, Csaba Kónya, Zsolt A. Borostyánkői, Tamás J. Görcs, Márta Zarándi, Botond Penke, Brian E. Leonard, Paul G.M. Luiten   +10 more
doaj   +1 more source

A scoping review of adverse events associated with concomitant beta‐adrenoreceptor blockers and selective serotonin reuptake inhibitors

British Journal of Clinical Pharmacology, EarlyView.
Beta‐adrenoreceptor blockers (beta‐blockers) and selective serotonin reuptake inhibitors (SSRIs) are commonly used medications and often used together, such as for the treatment of anxiety. However, there is no recent review of any potential adverse events related to concomitant use of medicines from each group.
Ziyi Cai, James Sutton, Charlotte Archer, Caroline S. Copeland, Joseph Hayes, Charles E. Leonard, Nicky Lidbetter, Kenneth K. C. Man, Faraz Mughal, Ian C. K. Wong, Hayley C. Gorton   +10 more
wiley   +1 more source

Serotonin Deficiency Exacerbates Acetaminophen-Induced Liver Toxicity In Mice [PDF]

, 2015
Acetaminophen (APAP) overdose is a major cause of acute liver failure. Peripheral 5-hydroxytryptamine (serotonin, 5-HT) is a cytoprotective neurotransmitter which is also involved in the hepatic physiological and pathological process. This study seeks to
Liu, Sushun, Zhang, Ruiyao, Zhou, Lei, Zhang, Jingyao, Meng, Fandi, Pang, Qing, Song, Sidong, Wu, Qifei, Liu, Chang   +8 more
core   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

Demystifying serotonin syndrome (or serotonin toxicity).

Canadian family physician Medecin de famille canadien, 2019
To review the symptoms of serotonin toxicity (commonly referred to as serotonin syndrome) and the causative drugs and their mechanisms of action, and to equip primary care providers with practical strategies to prevent and identify serotonin toxicity.PubMed and Google Scholar were searched for relevant articles on serotonin toxicity, the causes, and ...
Ai-Leng, Foong, Kelly A, Grindrod, Tejal, Patel, Jamie, Kellar   +3 more
openaire   +1 more source

Activation of serotonin 5-HT7 receptor induces coronary flow increase in isolated rat heart

, 2017
Serotonin (5-Hydroxytryptamine, 5-HT) can elicit both vasoconstrictive and relaxant responses on rat coronary artery. The constrictive response has been well discussed, but the mechanism of relaxant response is less studied.
Chien, Ching-Chia Chang;Hsin, Ling-Wei;Su, Ming-Jai, 忻凌偉;蘇銘嘉   +1 more
core   +1 more source

Innovation of plant‐derived extracellular vesicles and interdisciplinary research: From discovery to biomedical applications

BMEMat, EarlyView.
Plant‐derived extracellular vesicles offer numerous advantages and are regarded as highly promising candidates in the field of biomedicine. Abstract Extracellular vesicles (EVs) are double‐membrane vesicular structures that can be secreted by nearly all living cells.
Zilin Li, Yi Wei, Ben Hu, Yafang Song, Xiaojia Chen, Nik Ahmad Nizam Nik Malek, Tongkai Chen   +6 more
wiley   +1 more source

A Case of the Blues: Serotonin toxicity caused by the use of methylene blue and antidepressants

, 2011
My research at UIC is studying digital art tools and how they are used to address the visualization of scientific research. I use 3D modeling and digital painting tools to create pieces addressing problems within the medical field.
Melissa Sisk (7916765)
core   +3 more sources

Comparison of serotonin toxicity with concomitant use of either linezolid or comparators and serotonergic agents: an analysis of Phase III and IV randomized clinical trial data.

, 2012
Click on the Resource Link to access the article (may not be free).OBJECTIVES AND METHODS: The present study's objective was to evaluate serotonin toxicity with concomitant use of linezolid or comparators and serotonergic agents from 20 Phase III and IV ...
Butterfield-Cowper, Jill M, Thompson, Charles A, Lodise, Thomas P, Lawrence, Kenneth R, Reisman, Arlene, Huang, David B   +5 more
core   +1 more source

The influence of circadian variables on ecotoxicology metabolomics

Biological Reviews, EarlyView.
ABSTRACT Ecotoxicologists are using metabolomics increasingly to gain insight into toxicological mechanisms and sublethal effects of chemical exposures. Metabolomics offers a sensitive multi‐parameter approach that can detect biochemical responses not obvious using apical and behavioural endpoints.
Ryan I. Lester, David J. Beale, Anthony R. Carroll, Steven D. Melvin   +3 more
wiley   +1 more source