Results 261 to 270 of about 2,926,392 (292)

Significance of Serotonin Transporter Gene Polymorphism in Tinnitus

Otology & Neurotology, 2010
To assess the role of serotonin transporter gene (SLC6A4) polymorphism in tinnitus.Fifty-four consecutive patients experiencing subjective tinnitus and 174 healthy controls were allocated for the study. Psychoacoustic parameters of tinnitus were measured. Beck Depression Inventory was used to assess the depression level of the patients.
Karabulut, Hayriye, Celenk, Fatih, Deniz, Murat, Bayazit, Yildirim A., Yilmaz, Akin, Saridogan, Cagil, Dagli, Muharrerm, Erdal, Emin, Menevse, Adnan, GÜNDÜZ, BÜLENT   +9 more
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Serotonin transporter gene is not associated with symptomatology of schizophrenia

Schizophrenia Research, 1999
The serotonin transporter gene is a primary candidate for involvement in major psychoses. A functional polymorphism in the upstream regulatory region of the serotonin transporter gene (5-HTTLPR) has recently been reported to be associated with a variety of psychopathological conditions.
A, Serretti, M, Catalano, E, Smeraldi
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Association of the Serotonin Transporter Gene With Smoking Behavior

American Journal of Psychiatry, 2005
In an ongoing molecular genetic study of temperament, participants were genotyped to examine the association of smoking with two polymorphisms of the serotonin transporter gene (SERT): the promoter region, 5-HTTLPR, and an intronic variable-number-of-tandem-repeats region (VNTR).Full information was available for 330 families, and 244 "ever smokers ...
Ilana, Kremer, Rachel, Bachner-Melman, Alon, Reshef, Leonid, Broude, Lubov, Nemanov, Inga, Gritsenko, Uriel, Heresco-Levy, Yoel, Elizur, Richard P, Ebstein   +8 more
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Serotonin transporter and serotonin receptor 2A gene polymorphisms in Alzheimer's disease

Neuroscience Letters, 2013
Genetic variants of the serotonergic neurotransmitter system are potential contributing factors in the pathological processes underlying Alzheimer's disease (AD). We examined polymorphisms of the serotonin transporter (SLC6A4) and serotonin receptor 2A (HTR2A) genes for possible association with AD, and therefore genotyped 5-HTTLPR, STin2-VNTR and ...
Agnes, Fehér, Anna, Juhász, Anna, László, Magdolna, Pákáski, János, Kálmán, Zoltán, Janka   +5 more
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Serotonin Transporter Gene Variants and Behavior: A Comprehensive Review

Current Drug Targets, 2006
The serotonin system modulates affective, cognitive and behavioral processes. A key molecular structure of this system, the serotonin transporter (SERT) gene, has been associated with many human behaviors, both normal and pathological. This article aim is a comprehensive overview of the human behavioral features influenced by SERT gene variants and to ...
SERRETTI, ALESSANDRO, CALATI, RAFFAELLA, MANDELLI, LAURA, DE RONCHI, DIANA   +3 more
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Depression vulnerability, cigarette smoking, and the serotonin transporter gene

Addictive Behaviors, 2005
People with current or past depression are more likely to have been smokers at some point in their lives. Smokers with depression histories are also less likely to quit. Attempts to understand this relationship are important insofar as they can help treatment efficacy for this group of smokers. Prior research indicates that different genetic variations
Cindy L, Brody, Dean H, Hamer, David A F, Haaga   +2 more
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Allelic Variation of Human Serotonin Transporter Gene Expression

Journal of Neurochemistry, 1996
Abstract: Mood, emotion, cognition, and motor functions as well as circadian and neuroendocrine rhythms, including food intake, sleep, and reproductive activity, are modulated by the midbrain raphe serotonin (5‐HT) system.
A, Heils, A, Teufel, S, Petri, G, Stöber, P, Riederer, D, Bengel, K P, Lesch   +6 more
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Serotonin transporter gene polymorphisms and treatment-resistant depression

Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2010
Major Depression Disorder (MDD) is a serious mental illness that is one of the most disabling diseases worldwide. In addition, approximately 15% of depression patients are defined treatment-resistant (TRD). Preclinical and genetic studies show that serotonin modulation dysfunction exists in patients with TRD.
Bonvicini C, MINELLI, Alessandra, Scassellati C, Bortolomasi M, Segala M, Sartori R, Giacopuzzi M, GENNARELLI, Massimo   +7 more
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Serotonin transporter gene polymorphisms, alcoholism, and suicidal behavior

Biological Psychiatry, 2000
Dysfunction of serotoninergic transmission could predispose to excessive alcohol consumption and dependence. The functional polymorphism of the serotonin transporter gene (5-HTTLPR) has been associated with different disorders, including alcoholism. Considering the likelihood of heterogeneity in the "alcohol dependence" phenotype, 5-HTTLPR may be more ...
P, Gorwood, P, Batel, J, Adès, M, Hamon, C, Boni   +4 more
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Looking on the Bright Side of Serotonin Transporter Gene Variation

Biological Psychiatry, 2011
Converging evidence indicates an association of the short (s), low-expressing variant of the repeat length polymorphism, serotonin transporter-linked polymorphic region (5-HTTLPR), in the human serotonin transporter gene (5-HTT, SERT, SLC6A4) with anxiety-related traits and increased risk for depression in interaction with psychosocial adversity across
Homberg, J.R., Lesch, K.P.
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