Results 121 to 130 of about 24,818 (268)
Allergy, EarlyView.Ritlecitinib modulated Type I/II immunity genes (CCL5, CD8A, GZMB, CCL13, CCL18, and IL13RA1), MoA genes (JAK3, ITK, and BTK), and upregulated hair keratins, with stronger effects in AAP than AT/AU. Baseline and longitudinal scalp and serum protein changes correlated with hair regrowth and disease improvement.
Li Xi +6 more
wiley +1 more source
CemOrange2 fusions facilitate multifluorophore subcellular imaging in C. elegans [PDF]
, 2019 Due to its ease of genetic manipulation and transparency, Caenorhabditis elegans (C. elegans) has become a preferred model system to study gene function by microscopy.
Buland, Justin R +14 more
core +3 more sources
Expression of maspin in benign and malignant salivary gland tumors: An immunohistochemical study
Indian Journal of Dental Research, 2014 Context: Maspin is a novel serine protease inhibitor (serpin) with multifaceted tumor-suppressive activities. It was originally identified in normal human breast myoepithelial cells and shows variable expression in different types of cancer cells. Maspin
V Reshma +5 more
doaj +1 more source
Membrane Phospholipids and Polyphosphates as Cofactors and Binding Molecules of SERPINA12 (vaspin)
Molecules, 2020 Visceral adipose tissue derived serine protease inhibitor (vaspin) is a member of the serpin family and has been shown to have beneficial effects on glucose tolerance, insulin stability as well as adipose tissue inflammation, parameters seriously ...
Catherine A. Tindall +6 more
doaj +1 more source
Occupational Mite Allergy and Asthma: An EAACI Task Force Report
Allergy, EarlyView.ABSTRACT Mite sensitization is notable in several occupational settings. Elevated house dust mite concentrations are primarily detected in workplaces where people congregate and are active. Allergy to storage mites and spider mites has commonly been reported in agricultural and various food processing occupations.
Hille Suojalehto +8 more
wiley +1 more source
Journal of Biological Chemistry, 2017 Enduring host-microbiome relationships are based on adaptive strategies within a particular ecological niche. Tannerella forsythia is a dysbiotic member of the human oral microbiome that inhabits periodontal pockets and contributes to chronic ...
T. Goulas +7 more
semanticscholar +1 more source
Allergy, EarlyView.This study described the expression and function of TSLP and IL‐33 in an experimental model of EoE. TSLP and IL‐33 were overexpressed in human and experimental EoE. Human and mouse esophageal MCs displayed the highest level of Crlf2 (TSLPR) compared to other immune cells.
Anish Dsilva +16 more
wiley +1 more source
The role of serpins in vertebrate immunity [PDF]
Tissue Antigens, 2008 AbstractSerine proteases are important components of the immune system, playing a role in many processes including migration, phagocytosis and elimination of virally infected and cancerous cells. Members of the serpin superfamily regulate the activity of these proteases to limit tissue damage and unwarranted cell death.
Phillip I. Bird +2 more
openaire +3 more sources
Protein accumulation in the endoplasmic reticulum as a non-equilibrium phase transition [PDF]
, 2014 Several neurological disorders are associated with the aggregation of aberrant proteins, often localized in intracellular organelles such as the endoplasmic reticulum.
Budrikis, Z. +3 more
core +2 more sources
Diagnostics of Autoimmune Hepatitis Enabled by Non‐Invasive Clinical Proteomics
Alimentary Pharmacology &Therapeutics, EarlyView.Mass‐spectrometry‐based proteomic analyses of paired liver‐plasma samples from patients with AIH enabled discovery of numerous proteins showing high diagnostic accuracy. Proteomics may constitute a novel non‐invasive diagnostic tool for AIH if validated in larger, age‐ and sex‐matched cohorts.
Anne‐Sofie Houlberg Jensen +20 more
wiley +1 more source