Results 11 to 20 of about 43,231 (331)

Elevated cerebrospinal fluid levels of SERPIN E1 in participants with lewy body diseases [PDF]

npj Parkinson's Disease
Parkinson’s disease (PD) exhibits substantial phenotypic variability, likely influenced, at least in part, by proteins associated with pathways integral to aging processes.
Milan Zimmermann, Madeleine Fandrich, Meike Jakobi, Benjamin Röben, Isabel Wurster, Stefanie Lerche, Claudia Schulte, Shahrzad Zimmermann, Christian Deuschle, Nicole Schneiderhan-Marra, Thomas O. Joos, Thomas Gasser, Kathrin Brockmann   +12 more
doaj   +2 more sources

Arginine Inhibits Serpins [PDF]

Clinical and Applied Thrombosis/Hemostasis, 2007
Serine protease inactivators (serpins) are important regulators in biochemistry. Often it is necessary to block the serpin action, that is, to stabilize the sample. The guanidine group of arginine is the ligand for the active center pocket of many serine proteases.
T. Stief
openalex   +3 more sources

Amblyomma americanum serpin 27 (AAS27) is a tick salivary anti-inflammatory protein secreted into the host during feeding

PLoS Neglected Tropical Diseases, 2019
Ticks successfully feed and transmit pathogens by injecting pharmacological compounds in saliva to thwart host defenses. We have previously used LC-MS/MS to identify proteins that are present in saliva of unfed Amblyomma americanum ticks that were ...
Lucas Tirloni, Tae Kwon Kim, Markus Berger, Carlos Termignoni, Itabajara da Silva Vaz, Albert Mulenga   +5 more
openalex   +3 more sources

Comparison of structures and inhibition activities of serine protease inhibitors of Trichinella spiralis and Trichinella pseudospiralis [PDF]

Cell & Bioscience
Background Trichinosis is one of the most widespread parasitic infections worldwide. Trichinella spiralis not only infects humans but can also utilize wild anddomestic animals as hosts. The serine protease inhibitors secreted by Trichinella spiralis play
Ruixue Li, Bing Zhang, Chen Chen
doaj   +2 more sources

Species-Specific Serological Detection for Schistosomiasis by Serine Protease Inhibitor (SERPIN) in Multiplex Assay. [PDF]

PLoS Neglected Tropical Diseases, 2015
Both Schistosoma mansoni and Schistosoma haematobium cause schistosomiasis in sub-Saharan Africa. We assessed the diagnostic value of selected Schistosoma antigens for the development of a multiplex serological immunoassay for sero-epidemiological ...
Chihiro Tanigawa, Yoshito Fujii, Masashi Miura, Samson Muuo Nzou, Anne Wanjiru Mwangi, Sachiyo Nagi, Shinjiro Hamano, Sammy M Njenga, Evaristus Chibunna Mbanefo, Kenji Hirayama, Matilu Mwau, Satoshi Kaneko   +11 more
doaj   +2 more sources

Serpin B9 is Highly Expressed in Lung Adenocarcinoma and is Associated with Progression-Free Survival [PDF]

Journal of Inflammation Research
Yue Fang,1,2,* Yi Yue,3,* Sensen Hao,1 Ying Zhang,4 Nan Liu,1 Shengling Wang,1 Yan Li,1 Hongzhi Wang1 1Galactophore Oncology Center, Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei City, Anhui Province, People’s Republic of China ...
Fang Y, Yue Y, Hao S, Zhang Y, Liu N, Wang S, Li Y, Wang H   +7 more
doaj   +2 more sources

Molecular mechanisms of antithrombin–heparin regulation of blood clotting proteinases. A paradigm for understanding proteinase regulation by serpin family protein proteinase inhibitors

Biochimie, 2010
Steven T Olson, Gonzalo Izaguirre
exaly   +3 more sources

Nanoparticles Encapsulated with LL37 and Serpin A1 Promotes Wound Healing and Synergistically Enhances Antibacterial Activity

Molecular Pharmaceutics, 2016
Emmanuel A Ho
exaly   +2 more sources

SERPIN-Derived Small Peptide (SP16) as a Potential Therapeutic Agent against HIV-Induced Inflammatory Molecules and Viral Replication in Cells of the Central Nervous System

Cells, 2023
Despite the success of combined antiretroviral therapy (cART) increasing the survival rate in human immunodeficiency virus (HIV) patients, low levels of viremia persist in the brain of patients leading to glia (microglia and astrocytes)-induced ...
Yemmy Soler, Myosotys Rodriguez, Dana Austin, Cyrille Gineste, Cohava Gelber, Nazira El-Hage   +5 more
doaj   +1 more source

Serpin-1a and serpin-6 regulate the Toll pathway immune homeostasis by synergistically inhibiting the Spätzle-processing enzyme CLIP2 in silkworm, Bombyx mori

PLoS Pathogens, 2023
The Toll receptor signaling pathway is an important innate immune response of insects to pathogen infection; its extracellular signal transduction involves serine protease cascade activation.
Huawei Liu, Jiahui Xu, Luoling Wang, P. Guo, Zhangchen Tang, Xiaotong Sun, Xin Tang, Wei Wang, Lingyan Wang, Yang Cao, Qingyou Xia, Ping Zhao   +11 more
semanticscholar   +1 more source