Serpins from wheat grain [PDF]
FEBS Letters, 1994 Wheat serpin genes have been identified by Southern blot hybridization with three distinct barley protein Z probes. Immunoblot analysis with a monoclonal antibody towards barley protein Z confirmed expression of related M r ~ 40 kDa proteins in wheat grain.
Rosenkrands, Ida +3 more
openaire +2 more sources
The stability and activity of human neuroserpin are modulated by a salt bridge that stabilises the reactive centre loop [PDF]
, 2015 Neuroserpin (NS) is an inhibitory protein belonging to the serpin family and involved in several pathologies, including the dementia Familial Encephalopathy with Neuroserpin Inclusion Bodies (FENIB), a genetic neurodegenerative disease caused by ...
Caccia, Sonia +7 more
core +1 more source
Frontiers in Cardiovascular Medicine, 2021 Alpha-1 antitrypsin (AAT, also known as alpha-1 proteinase inhibitor or SERPINA1) is the most abundant member of the serpin superfamily found in human plasma.
Mostafa Hamada +4 more
doaj +1 more source
Serpina3c Mitigates Adipose Tissue Inflammation by Inhibiting the HIF1α-Mediated Endoplasmic Reticulum Overoxidation in Adipocytes [PDF]
Diabetes & Metabolism JournalBackground Visceral white adipose tissue (vWAT) inflammation is a critical pathology of obesity-caused heart damage and is closely associated with adipocyte endoplasmic reticulum (ER) dysfunction. Serine (or cysteine) peptidase inhibitor, clade A, member
Yu Jiang +7 more
doaj +1 more source
Heparin Blocks the Inhibition of Tissue Kallikrein 1 by Kallistatin through Electrostatic Repulsion
Biomolecules, 2020 Kallistatin, also known as SERPINA4, has been implicated in the regulation of blood pressure and angiogenesis, due to its specific inhibition of tissue kallikrein 1 (KLK1) and/or by its heparin binding ability.
Lina Ma +7 more
doaj +1 more source
Identification and in-silico characterization of Serpin genes in legumes genomes
The Indian Journal of Agricultural Sciences, 2020 Serine protease inhibitors (serpins) are a unique family of protease inhibitor containing mobile reactive center loop. The availability of genome sequences of pigeonpea, soybean, commanbean, cowpea, mungbean and adzuki bean provided an opportunity to ...
PAWAN S MAINKAR +5 more
doaj +1 more source
SerpinB3 and Yap Interplay Increases Myc Oncogenic Activity [PDF]
, 2015 SerpinB3 has been recently described as an early marker of liver carcinogenesis, but the potential mechanistic role of this serpin in tumor development is still poorly understood.
Biasiolo, Alessandra +16 more
core +2 more sources
Remote Pancreatic Response to Severe Polytrauma Correlates With Clinical Outcome. [PDF]
United European Gastroenterol JABSTRACT Background Acute pancreatic injury can result from blunt or sharp force trauma, often leading to serious complications. While direct pancreatic trauma is associated with high rates of infection, organ failure, and mortality, little is known about the pancreas as a potential secondary target and remote trauma organ and thereby as a booster of ...
Halbgebauer R +17 more
europepmc +2 more sources
Serpins in thrombosis, hemostasis and fibrinolysis
Journal of Thrombosis and Haemostasis, 2007 Jill C. Rau +3 more
openalex +2 more sources
A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells
Advanced Science, EarlyView.An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet +5 more
wiley +1 more source