Results 1 to 10 of about 72,366 (294)

Rare Opportunities for Insights Into Serotonergic Contributions to Brain and Bowel Disorders: Studies of the SERT Ala56 Mouse

Frontiers in Cellular Neuroscience, 2021
Altered structure, expression, and regulation of the presynaptic serotonin (5-HT) transporter (SERT) have been associated with multiple neurobehavioral disorders, including mood disorders, obsessive-compulsive disorder (OCD), and autism spectrum disorder
Randy D. Blakely, Samantha E Stilley
exaly   +3 more sources

The dynamics of Sert, Htr4a, and Bdnf genes expression in the blood of rats under chronic stress exposure

Учёные записки Казанского университета: Серия Естественные науки, 2022
In this article, we discuss the expression levels of Sert, Htr4a, and Bdnf genes in the blood of Wistar rats exposed to the following types of chronic stresses for 270 days: swimming with a load and immobilization, as well as the combination of these two
E.V. Valeeva, I.I. Semina , A.G. Galeeva, O.A. Kravtsova   +3 more
doaj   +1 more source

STUDY MOLECULES DOCKING OF ALKALOIDS IN KRATOM ON SEROTONIN TRANSPORTER (SERT), NOREPINEPHRINE TRANSPORTER (NET), AND MONOAMINE OXIDASE (MAO)

Jurnal Kimia Riset, 2023
Kratom (Mitragyna speciosa Korth) is a tropical plant originating from Southeast Asia that predominantly contains alkaloid compounds and can potentially maintain levels of monoamine compounds in the body to treat depression.
Dandi Irawan, Bambang Wijianto, Harianto IH   +2 more
doaj   +1 more source

Syntaxin 3 interacts with serotonin transporter and regulates its function

Journal of Pharmacological Sciences, 2021
Herein, we investigated the functional association of the serotonin transporter (SERT) with syntaxin-3 (STX3). We first overexpressed SERT and STX3 in various cells and examined their interaction, localization, and functional association ...
Serika Motoike, Kei Taguchi, Kana Harada, Masaya Asano, Izumi Hide, Shigeru Tanaka, Masahiro Irifune, Norio Sakai   +7 more
doaj   +1 more source

The Extent of Social Responsibility among Libyan and Palestinian Telecom Companies in Mitigating the Effects of the COVID-19 Pandemic

المجلة الأردنية للعلوم التطبيقية-العلوم الانسانية, 2022
This study primarily aims to identify the social responsibility of Libyan and Palestinian telecommunications companies and their contributions to addressing the negative effects resulting from COVID-19.
Abdelrahman Rashwan, Suad Amarif
doaj   +1 more source

Univariate Interpolation-based Modeling of Power and Performance

EAI Endorsed Transactions on Energy Web, 2016
Performance and power scale non-linearly with device utilization, making characterization and prediction of energy efficiency at a given load level a challenging issue.
Jóakim von Kistowski, Samuel Kounev
doaj   +1 more source

Synthesis of Novel Nicotinic Ligands with Multimodal Action: Targeting Acetylcholine α4β2, Dopamine and Serotonin Transporters

Molecules, 2019
Nicotinic acetylcholine receptors (nAChRs), serotonin transporters (SERT) and dopamine transporters (DAT) represent targets for the development of novel nicotinic derivatives acting as multiligands associated with different health conditions, such as ...
Juan Pablo González-Gutiérrez, Hernán Armando Pessoa-Mahana, Patricio Ernesto Iturriaga-Vásquez, Miguel Iván Reyes-Parada, Nicolas Esteban Guerra-Díaz, Martin Hodar-Salazar, Franco Viscarra, Pablo Paillali, Gabriel Núñez-Vivanco, Marcos Antonio Lorca-Carvajal, Jaime Mella-Raipán, María Carolina Zúñiga   +11 more
doaj   +1 more source

Pharmacological Studies on the Role of 5-HT1A Receptors in Male Sexual Behavior of Wildtype and Serotonin Transporter Knockout Rats

Frontiers in Behavioral Neuroscience, 2020
Brain serotonin (5-HT) neurotransmission plays an important role in male sexual behavior and it is well established that activating 5-HT1A receptors in rats facilitate ejaculatory behavior.
Diana Carolina Esquivel-Franco, Diana Carolina Esquivel-Franco, Diana Carolina Esquivel-Franco, Sietse F. de Boer, Marcel Waldinger, Berend Olivier, Berend Olivier, Berend Olivier, Jocelien D. A. Olivier   +8 more
doaj   +1 more source

Mechanisms of Intestinal Serotonin Transporter (SERT) Upregulation by TGF-β1 Induced Non-Smad Pathways. [PDF]

PLoS ONE, 2015
TGF-β1 is an important multifunctional cytokine with numerous protective effects on intestinal mucosa. The influence of TGF-β1 on serotonin transporter (SERT) activity, the critical mechanism regulating the extracellular availability of serotonin (5-HT),
Saad Nazir, Anoop Kumar, Ishita Chatterjee, Arivarasu N Anbazhagan, Tarunmeet Gujral, Shubha Priyamvada, Seema Saksena, Waddah A Alrefai, Pradeep K Dudeja, Ravinder K Gill   +9 more
doaj   +1 more source

The role of genetic factors in predicting results of obesity treatment with sibutramine – serotonin-norepinephrine reuptake inhibitor

Ожирение и метаболизм, 2016
Aim. To study the influence of SERT and GNB3 gene polymorphisms on the results of the treatment of obesity by serotonin-norepinephrine reuptake inhibitors.Methods.
Marina Galieva, Ekaterina Troshina, Nataliya Mazurina, Andrey Artiushin, Anastasia Pavlova, Anna Volynkina, Marina Aksyonova, Oksana Logvinova   +7 more
doaj   +1 more source