Results 11 to 20 of about 72,366 (294)

Long-Term Exposure of RN46A Cells Expressing Serotonin Transporter (SERT) to a cAMP Analog Up-regulates SERT Activity and Is Accompanied by Neural Differentiation of the Cells

Journal of Pharmacological Sciences, 2013
To examine the functional regulation of serotonin transporter (SERT) by cAMP, we examined whether SERT uptake activity was affected by dibutyryl cAMP (dbcAMP), a cAMP analog, in SERT-transfected RN46A cells derived from embryonic rat raphe neurons.
Hikaru Yammamoto, Shigeru Tanaka, Anna Tanaka, Izumi Hide, Takahiro Seki, Norio Sakai   +5 more
doaj   +2 more sources

Expanded characterization of the valproic acid zebrafish larval model of autism spectrum disorder: Insights into dysregulation in the gut [PDF]

Animal Model Exp Med
Meticulous calculation of zebrafish‐equivalent therapeutic valproic acid (VPA) dosage maximized the translational value of the data. Hyposerotonergic tone underpinned an anxiety‐like outcome as a core symptom of autism spectrum disorder (ASD). Compartment‐specific dopaminergic and serotonergic dysregulation in the brain versus gut provided mechanistic ...
Pretorius L, Coetzee J, dos Santos A, Smith C.   +3 more
europepmc   +2 more sources

Seconds-resolved in vivo measurements reveal rapid, serotonin transporter–independent plasma serotonin clearance [PDF]

Blood Vessels, Thrombosis & Hemostasis
: Serotonin potently regulates vascular tone, permeability, and platelet activation. Because of this, circulating plasma-free serotonin is normally maintained at very low concentrations through rapid, serotonin transporter (SERT)–mediated uptake into ...
Olena Lukoyanova, Rose Mery Bakestani, Nicole A. Emmons, Chelsea N. Brown, Dallin Ostler, Kaitlyn An, Kevin W. Plaxco, Tod E. Kippin   +7 more
doaj   +2 more sources

Josep Lluís Sert [PDF]

DC Papers. Revista de crítica i teoria de l'arquitectura, 2005
Reseña del libro de Jaume Freixa. Josep LLuís Sert.
García Estévez, Carolina Beatriz
core   +4 more sources

Implementation and Evaluation of the First Renewable Energy Systems Technical Course in Brazil

IEEE Access, 2019
Availability of skilled labor in renewable energies (REs) is a necessity for countries that, in search of sustainable development, intend to invest in this segment.
Manuel R. B. Neto, Paulo C. M. Carvalho, Ricardo M. Costa   +2 more
doaj   +1 more source

Differential regulation of the serotonin transporter by vesicle-associated membrane protein 2 in cells of neuronal versus non-neuronal origin. [PDF]

PLoS ONE, 2014
The serotonin transporter (SERT) is a key regulator of serotonergic signalling as it mediates the re-uptake of synaptic serotonin into nerve terminals, thereby terminating or modulating its signal.
Heidi Kaastrup Müller, Marie Kragballe, Anja Winther Fjorback, Ove Wiborg   +3 more
doaj   +1 more source

The C-Terminal Region of Serotonin Transporter Is Important for Its Trafficking and Glycosylation

Journal of Pharmacological Sciences, 2009
We investigated the effects of brefeldin A and ilimaquinone, inhibitors of membrane trafficking, using serotonin transporter (SERT)–expressing COS-7 cells.
Mariko Nobukuni, Hideki Mochizuki, Satoshi Okada, Nobuhisa Kameyama, Anna Tanaka, Hikaru Yamamoto, Taku Amano, Takahiro Seki, Norio Sakai   +8 more
doaj   +1 more source

SAHA Alleviates Diarrhea-Predominant Irritable Bowel Syndrome Through Regulation of the p-STAT3/SERT/5-HT Signaling Pathway

Journal of Inflammation Research, 2022
Jian Shen,1 Bimeng Zhang,2 Jianjie Chen,3 Jiazheng Cheng,1 Jiali Wang,1 Xianhui Zheng,1 Yu Lan,1 Xiaowen Zhang1 1Department of Pediatrics, Shuguang Hospital Affiliated to Shanghai Traditional Chinese Medical University, Shanghai, 201203, People’s ...
Shen J, Zhang B, Chen J, Cheng J, Wang J, Zheng X, Lan Y, Zhang X   +7 more
doaj  

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant

Frontiers in Molecular Neuroscience, 2020
Altered serotonin (5-HT) signaling is associated with multiple brain disorders, including major depressive disorder (MDD), obsessive-compulsive disorder (OCD), and autism spectrum disorder (ASD).
Meagan A. Quinlan, Meagan A. Quinlan, Meagan A. Quinlan, Matthew J. Robson, Ran Ye, Kristie L. Rose, Kevin L. Schey, Randy D. Blakely, Randy D. Blakely   +8 more
doaj   +1 more source

Architectural Interoperability in Industrial Automation: Toward Software-Defined Systems

IEEE Access
This paper presents a structured survey of the historical evolution of interoperability standards in industrial automation, examining how successive advances in control, programming, communication, cybersecurity, and execution infrastructures reshaped ...
Eduardo Andre Mossin, Rodrigo Palucci Pantoni, Afonso Celso Turcato   +2 more
doaj   +1 more source