Results 21 to 30 of about 72,366 (294)
PLoS ONE, 2012 Serotonin reuptake transporter (SERT) is a key regulator of serotonin neurotransmission and a major target of antidepressants. Antidepressants, such as selectively serotonin reuptake inhibitors (SSRIs), that block SERT function are known to affect food ...
Xiaoning Chen +4 more
doaj +1 more source
, 2014 A, Immobilized GST or GST fusion proteins of VAMP2, SNAP25, and syntaxin 1A were incubated with cell extracts from HEK-293 MSR cells transiently expressing SERT. Bound protein was eluted with SDS sample buffer, and SERT was detected by immunoblotting. B,
Marie Kragballe (570208) +3 more
core +1 more source
Frontiers in Pharmacology, 2018 Tramadol is an effective pharmacological intervention in human premature ejaculation (PE). To investigate whether the inhibitory action of tramadol is primarily caused by its selective serotonin reuptake inhibitory (SSRI) effects we tested the dose ...
Diana C. Esquivel-Franco +9 more
doaj +1 more source
The Serotonin Transporter and Early Life Stress: Translational Perspectives
Frontiers in Cellular Neuroscience, 2017 The interaction between the serotonin transporter (SERT) linked polymorphic region (5-HTTLPR) and adverse early life stressing (ELS) events is associated with enhanced stress susceptibility and risk to develop mental disorders like major depression ...
Jocelien D. A. Olivier +4 more
doaj +1 more source
Serotonin Transporter Defect Disturbs Structure and Function of the Auditory Cortex in Mice
Frontiers in Neuroscience, 2021 Serotonin transporter (SERT) modulates the level of 5-HT and significantly affects the activity of serotonergic neurons in the central nervous system.
Wenlu Pan +10 more
doaj +1 more source
Journal of Pharmacological Sciences, 2013 The serotonin transporter (SERT) is involved in various psychiatric disorders, including depression and autism. Recently, chemical chaperones have been focused as potential therapeutic drugs that can improve endoplasmic reticulum (ER) stress–related ...
Masayuki Fujiwara +6 more
doaj +1 more source
The cellular distribution of serotonin transporter is impeded on serotonin-altered vimentin network. [PDF]
PLoS ONE, 2009 BACKGROUND:The C-terminus of the serotonin transporter (SERT) contains binding domains for different proteins and is critical for its functional expression.
Billow A Ahmed +11 more
doaj +1 more source
Frontiers in Neuroscience, 2014 Context: That serotonin plays a role in the regulation of feeding behavior and energy metabolism has been known for a long time. Serotonin transporters (SERT) play a crucial role in serotonin signalling by regulating its availability in the synaptic ...
Anke eBorgers +7 more
doaj +1 more source
Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni +19 more
wiley +1 more source