Results 101 to 110 of about 72,366 (294)

SERT 2 solar array Final report [PDF]

, 1970
Performance tests of flight worthiness of SERT array ...

core  

Notoginsenoside‐Fa mitigates vascular endothelial permeability via targeting SUGT1 to stabilize NLRP3 in a resting state

British Journal of Pharmacology, EarlyView.
Background and Purpose Notoginsenoside‐Fa (Noto‐Fa) is an emerging active compound derived from notoginseng with promise in treating cardiovascular diseases. The development of cardiovascular diseases is intricately linked to the damage of vascular endothelium and it is widely acknowledged that numerous chronic inflammation pathways, especially the ...
Xiao‐Ying Yu, Da‐Hao Mai, Xing‐Ming Zhong, Li‐Ting Huang, Lan‐Ting Fu, He‐Cai Wang, Ke Wang, Hai‐Yan Li, Qiu‐He Chen, Yang Chen   +9 more
wiley   +1 more source

Physical Interactions and Functional Relationships of Neuroligin 2 and Midbrain Serotonin Transporters

Frontiers in Synaptic Neuroscience, 2016
The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) modulates many key brain functions including those subserving sensation, emotion, reward and cognition.
Ran eYe, Meagan A. Quinlan, Hideki eIwamoto, Hsiao-Huei eWu, Noah H. Green, Christopher S. Jetter, Douglas G. McMahon, Douglas G. McMahon, Jeremy eVeenstra-VanderWeele, Pat R. Levitt, Randy D. Blakely, Randy D. Blakely   +11 more
doaj   +1 more source

A quoi sert l'Epistémologie ?

Droit et société, 1992
On Epistemology. Epistemology, in the continental meaning of "Philosophy of the Sciences" has no direct effects indeed on the advancement of science. But it has an interest, which we propose to suggest, applying epistemology to the case of the social sciences.
openaire   +2 more sources

R/SERT

, 2016
A series of novel 3-indolylpropyl derivatives was synthesized and evaluated for their binding affinities at the serotonin-1A receptor subtype (5-HT1AR) and the 5-HT transporter (SERT). Compounds 11b and 14b exhibited the highest affinities at the 5-HT1AR
Zapata Torres, Gerald, Reyes Parada, Miguel, Pessoa Mahana, Hernán, Quiroz, Gabriel, Iturriaga Vásquez, Patricio, Patricio Iturriaga‐Vásquez, Pessoa Mahana, Carlos David, Araya Maturana, Ramiro, Claudio Saitz‐Barría, Gerald Zapata‐Torres, C. David Pessoa‐Mahana, Möller Acuña, Patricia, Hernán Pessoa‐Mahana, Gabriel Quiroz, Chung, Hery, Hery Chung, Ramiro Araya‐Maturana, Silva Matus, Paul, Saitz Barría, Claudio Antonio, Patricia Möller‐Acuña, Miguel Reyes‐Parada, Paul Silva‐Matus, Saitz-Barría C., Iturriaga-Vásquez P., Zapata-Torres G., Chung H., Silva-Matus, Paul, Möller-Acuña P., Reyes-Parada M., Pessoa-Mahana H., Araya-Maturana, Ramiro, Araya-Maturana R., Quiroz G., Iturriaga-Vasquez, Patricio, Pessoa-Mahana, Hernan, Silva-Matus P., Pessoa-Mahana C.D., Saitz-Barria, Claudio, Moller-Acuna, Patricia, Zapata-Torres, Gerald, David Pessoa-Mahana, C   +40 more
core   +1 more source

Inhibition of late sodium current prevents pathological hyperactivation of calcium/calmodulin‐dependent protein kinase IIδ in a murine model of acute doxorubicin‐related cardiotoxicity

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Doxorubicin (DOX) is a highly effective anthracycline, whose clinical application for cancer is limited by cardiotoxicity. The mechanisms underlying doxorubicin‐induced toxic cardiomyopathy (DICM) involve electrophysiological remodelling with intracellular Na+ overload because of increased late INa and hyperactivation of
Anna‐Lena Feder, Anna‐Maria Pfützenreuter, Lea Maria Funke, Maria Johanna Baier, Daniel Tarnowski, Laura Stengel, Lars Siegfried Maier, Can Martin Sag   +7 more
wiley   +1 more source

Effects of cortisol and brain-derived neurotropic factor on the serotonin transporter in the midbrain of bipolar I disorder

Psychiatry and Clinical Psychopharmacology, 2021
Objective: Studies have demonstrated an association between cortisol levels and availability of the serotonin transporter (SERT) in healthy subjects and in those with major depressive disorder (MDD). We evaluated if this association could be observed in
Yi An Tu, Shyh Jen Wang, Yuan Hwa Chou
doaj  

Description of SERT 2 spacecraft and mission [PDF]

, 1970
Mission objectives and systems analysis of SERT 2 ...
Goldman, R. G., Hawersaat, W. H., Gurski, G. S.   +2 more
core  

sGC stimulator BAY 41‐8543 improves survival and ventricular function in a rat model of doxorubicin‐induced cardiomyopathy with nephrotic syndrome

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Anthracyclines such as doxorubicin (DOXO) remain a cornerstone of cancer therapy but are associated with a high risk of cardiotoxicity and subsequent heart failure (HF). Impairment of NO/soluble guanylyl cyclase (sGC)/cGMP pathway has been reported in anthracycline‐induced cardiomyopathy.
Olga Gawrys, Petra Škaroupková, Soňa Kikerlová, Zdeňka Vaňourková, Martina Hüttl, Olga Lenčová, Kasin Yadunandam Anandam, Svenja Stomberg, Sönke Behrends, Barbara Szeiffová Bačová, Matúš Sykora, Lisa Dietz, Peter Sandner, Luděk Červenka, Martin Štěrba   +14 more
wiley   +1 more source

SERT 2 spacecraft electrical power system [PDF]

, 1971
Design and performance of SERT 2 spacecraft electrical power ...
Krawczyk, R. J.
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