Results 121 to 130 of about 72,366 (294)
Alamandine/MrgD pathway modulates gut–bone marrow axis in ageing
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Ageing is associated with colon epithelial barrier disruption and up‐regulation of myelopoiesis in the bone marrow (BM). Alamandine (Ala) and MrgD are novel members of the renin angiotensin system (RAS). This study tested the hypothesis that Ala restores the colon epithelial barrier integrity in ageing via modulating gut–
Kishore Chittimalli +6 more
wiley +1 more source
Treating myocardial infarction combined with depression via regulating M1/TNF-α/TNFR1/NF-κB
Biochemistry and Biophysics ReportsObjective: To further explore the underlying mechanism by which the traditional Mongolian medicine Anshen Buxin Liuwei Pills (ABLP) alleviates cardiac dysfunction and depressive behaviors in a model of myocardial infarction (MI) combined with depression.
Lijun Zhang, Meiyan Liu, Haiyang Chen
doaj +1 more source
, 2007 Cionus merkli Stierlin, 1882 Material: 1 specimen examined: 27.05. 1989, GüdülAnkara (Turkey), O. SERT. Genital spicule basally slight expanded; arms of eighth sternite lie parallel to each other, slightly expanded toward apex (Fig. 1); coxite narrow,
Sert, Osman
core +1 more source
TRPM3 regulates fear memory encoding and seizure susceptibility in the lateral amygdala
British Journal of Pharmacology, EarlyView.Abstract Background and purpose TRPM3 is best known for its role as a peripheral sensor of pain and heat. Recent studies reporting gain‐of‐function TRPM3 mutations in patients with neurodevelopmental and epilepsy‐associated disorders suggest a previously unrecognized role of this channel in the brain.
Attila Gyéresi +12 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Background and Purpose Degeneration of the pontine noradrenergic and midbrain dopaminergic systems contributes to cognitive‐behavioural disturbances during the prodromal stages of Alzheimer's disease (AD). We developed a genetically engineered, programmable probiotic Escherichia coli Nissle 1917 strain (EcNrhaL‐DOPA) capable of producing L‐3,4 ...
Mona Abdelhamid +9 more
wiley +1 more source
DOĞAL YİYECEKLER: SERT KABUKLU MEYVELER
, 2023 Türkiye diğer bazı meyvelerde olduğu gibi, sert kabuklu meyve türlerinde de Dünya'nın önde gelen üretici ülkelerinden birisidir. FAO 2021 verilerine göre, dünya sert kabuklu meyveler üretim oranlarına bakıldığında, Türkiye dünya fındık üretiminin %63,5'ini, cevizin %9,29'unu, bademin %4,46'ını, Antep fıstığının %13,03'ünü ve kestanenin ise %3,43'ünü ...
openaire +2 more sources
Gene sert e resposta a ISRS: é clinicamente útil?
O gene transportador de serotonina (SERT, 5-HTT, SLC6A4) pode influenciar a resposta aos SSRI e os efeitos colaterais, particularmente em homens caucasianos mais velhos.
Mercedes Guaia Memita Guaia
core +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose The metabotropic glutamate receptor mGlu5 plays an important role in neuronal survival and synaptic plasticity. We and others have shown that mGlu5 positive allosteric modulators (PAMs) are biased agonists, triggering the activation of neuroprotective pathways and promoting neuronal survival. As mGlu5 biased pharmacology
Jennifer D. S. Guimaraes +14 more
wiley +1 more source
Politique étrangère, 1995 L'OTAN s'accroche à des fonctions traditionnelles devenues sans objet et à de vieilles structures peu compatibles avec ses fonctions nouvelles. Si elle le fait, c'est parce que son vrai dessein est ailleurs : servir de cadre aux évolutions de l'Europe.
openaire +2 more sources