Results 41 to 50 of about 24,058 (175)

Impact of the novel CYP2C:TG haplotype and CYP2B6 variants on sertraline exposure in a large patient population

open access: yesClinical and Translational Science, 2022
Sertraline is a commonly used SSRI antidepressant drug, metabolized by CYP2C19 and CYP2B6, that exhibits a substantial interindividual variation in clinical response, of which only a part can be attributed to known genetic variants.
Line Skute Bråten   +4 more
doaj   +1 more source

Effect of sertraline on proliferation and neurogenic differentiation of human adipose-derived stem cells

open access: yesAdvanced Biomedical Research, 2014
Background: Antidepressant drugs are commonly employed for anxiety and mood disorders. Sertraline is extensively used as antidepressant in clinic. In addition, adipose tissue represents an abundant and accessible source of adult stem cells with the ...
Shahnaz Razavi   +3 more
doaj   +1 more source

Medication prescription patterns in cancer rehabilitation physiatry outpatients: A multicenter retrospective study

open access: yesPM&R, EarlyView.
Abstract Background and Objective Previous work from this dataset found 45% prescribing frequency of any medications (35.1%, 33.5%, and 56.8% at institutions 1, 2, and 3 respectively), without significant difference between in‐person and telemedicine.
Matthew Chen   +7 more
wiley   +1 more source

Comparative Efficacy of Elinzanetant Versus Other Non‐Hormonal Pharmaceutical Therapies for the Treatment of Moderate‐to‐Severe Vasomotor Symptoms Associated With Menopause: A Network Meta‐Analysis

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background Elinzanetant, a novel, dual neurokinin‐targeted therapy, has been approved in various geographies for the treatment of moderate‐to‐severe vasomotor symptoms (VMS) associated with menopause. Objective To compare the efficacy of elinzanetant with non‐hormonal pharmaceutical treatments (nHT) in alleviating VMS.
Piotr Wojciechowski   +8 more
wiley   +1 more source

Development of self-nanoemulsifying tablet (SNET) for bioavailability enhancement of sertraline

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2018
The purpose of the study was to combine the advantages of self-nanoemulsifying drug delivery systems and tablets as a conventional dosage form. Self-nanoemulsifying drug delivery system (SNEDDS) was prepared to enhance the solubility and thus oral ...
Mohammad Akhlaquer Rahman   +1 more
doaj   +1 more source

Predicting Response to Pro‐Cognitive Interventions in Mood Disorders: A Systematic Review by the International Society for Bipolar Disorders Targeting Cognition Task Force

open access: yesActa Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Major depressive disorder (MDD) and bipolar disorder (BD) are often associated with persistent cognitive deficits that impair psychosocial functioning. While pro‐cognitive interventions show promise, trial findings are inconsistent, potentially due to baseline factors influencing treatment response.
Dimosthenis Tsapekos   +30 more
wiley   +1 more source

Sertraline reduces IL-1β and TNF-α mRNA expression and overcomes their rise induced by seizures in the rat hippocampus.

open access: yesPLoS ONE, 2014
We recently discovered that the antidepressant sertraline is an effective inhibitor of hippocampus presynaptic Na+ channel permeability in vitro and of tonic-clonic seizures in animals in vivo. Several studies indicate that the pro-inflammatory cytokines
María Sitges   +2 more
doaj   +1 more source

Molecular Biomarkers Predictive of Sertraline Treatment Response in Young Children With Autism Spectrum Disorder

open access: yesFrontiers in Genetics, 2020
Sertraline is one among several selective serotonin reuptake inhibitors (SSRIs) that exhibited improvement of language development in Autism Spectrum Disorder (ASD); however, the molecular mechanism has not been elucidated.
Reem Rafik Alolaby   +8 more
doaj   +1 more source

Steatocystoma Multiplex Suppurativa—A Case Report and Review of Treatments

open access: yesAustralasian Journal of Dermatology, EarlyView.
ABSTRACT We report a case of Steatocystoma Multiplex Suppurativa (SMS), a rare condition that can mimic hidradenitis suppurativa (HS). We also present a review of the surgical and medical therapies, including potential biologic agents.
Justin Tam Vu, Alexis Daniel Lara Rivero
wiley   +1 more source

Ecchymosis due to sertraline use: a case report

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Sertraline is a widely used antidepressant due to its low adverse effect profile. Hematological adverse effects related to sertraline are uncommon. This report includes a case which presented to an emergency department with a large ecchymotic lesion on ...
Orhan Cinar   +4 more
doaj  

Home - About - Disclaimer - Privacy