Results 1 to 10 of about 337,086 (242)

Serum Amyloid A Protein–Associated Kidney Disease: Presentation, Diagnosis, and Management [PDF]

Kidney Medicine, 2022
Serum amyloid A protein (AA) amyloidosis, also known as secondary amyloidosis, is a known consequence of chronic inflammation and results from several conditions including inflammatory arthritis, periodic fever syndromes, and chronic infection.
Jordan Thorne, David Clark, Laurette Geldenhuys, Keigan More, Amanda Vinson, Karthik Tennankore   +5 more
doaj   +3 more sources

Presence of a SARS-CoV-2 Protein Enhances Amyloid Formation of Serum Amyloid A [PDF]

The Journal of Physical Chemistry B, 2021
ABSTRACTA marker for the severeness and disease progress of COVID-19 is overexpression of serum amyloid A (SAA) to levels that in other diseases are associated with a risk for SAA amyloidosis. In order to understand whether SAA amyloidosis could also be a long-term risk of SARS-COV-2 infections we have used long all-atom molecular dynamic simulations ...
Asis K. Jana, Augustus B. Greenwood, Ulrich H. E. Hansmann   +2 more
openaire   +5 more sources

RETRACTED: Serum amyloid A protein in the course of infectious mononucleosis

Therapeutic Advances in Infectious Disease, 2019
Serum amyloid A (SAA) protein is a major acute phase protein. Increased concentrations have been reported in many inflammatory diseases. In bacterial infections, high levels correlate with those of C-reactive protein (CRP). In viral infections, where CRP changes are weaker, SAA is of value for establishing early diagnosis, monitoring the severity, and ...
Iliyan Todorov, Margarita Gospodinova, Yana Bocheva, Gergana Popcheva   +3 more
doaj   +4 more sources

Serum amyloid A is a better predictive biomarker of mucosal healing than C-reactive protein in ulcerative colitis in clinical remission

BMC Gastroenterology, 2020
Background Many studies have revealed that mucosal healing improves the long-term prognosis of ulcerative colitis. Frequent colonoscopy is difficult because of its invasiveness and cost.
Masaki Wakai, Ryohei Hayashi, Shinji Tanaka, Toshikatsu Naito, Junko Kumada, Motonobu Nomura, Hidehiko Takigawa, Shiro Oka, Yoshitaka Ueno, Masanori Ito, Kazuaki Chayama   +10 more
doaj   +2 more sources

Aggregation of Mouse Serum Amyloid A Protein Was Promoted by Amyloid-Enhancing Factors with the More Genetically Homologous Serum Amyloid A. [PDF]

Int J Mol Sci, 2021
Amyloid A (AA) amyloidosis is a condition in which amyloid fibrils characterized by a linear morphology and a cross-β structure accumulate and are deposited extracellularly in organs, resulting in chronic inflammatory diseases and infections. The incidence of AA amyloidosis is high in humans and several animal species.
Lin X, Watanabe K, Kuragano M, Tokuraku K.   +3 more
europepmc   +4 more sources

C-reactive protein and serum amyloid A protein as complementary biomarkers in differentiating viral and bacterial community-acquired pneumonia in children [PDF]

BMC Pediatrics
Objective Distinguishing between viral and bacterial community-acquired pneumonia (CAP) in children is crucial for guiding targeted management and antibiotic use.
Juan Cheng, Ying Wu, Hui Ma, Mingyu Tang, Yufen Wu, Yong Yin, Qiuhui Pan, Qizhi Diao, Jing Zhang   +8 more
doaj   +2 more sources

Serum Amyloid A Protein Concentration in Blood is Influenced by Genetic Differences in the Cheetah (Acinonyx jubatus). [PDF]

J Hered, 2016
Systemic amyloid A (AA) amyloidosis is a major cause of morbidity and mortality among captive cheetahs. The self-aggregating AA protein responsible for this disease is a byproduct of serum amyloid A (SAA) protein degradation. Transcriptional induction of
Franklin AD, Schmidt-Küntzel A, Terio KA, Marker LL, Crosier AE.   +4 more
europepmc   +2 more sources

SERUM AMYLOID A PROTEIN

Transplantation, 1983
Acute human renal allograft rejection induces a dramatic elevation of serum amyloid A protein (SAA). To evaluate the clinical significance of this finding we monitored 31 consecutive recipients of cadaveric renal allografts by daily SAA measurements. SAA increased significantly during 37/38 rejection episodes.
C P, Maury, A, Teppo, B, Eklund, J, Ahonen   +3 more
openaire   +3 more sources

Serum amyloid A protein in acute viral infections. [PDF]

Archives of Disease in Childhood, 1993
Concentrations of serum amyloid A protein (SAA) were measured in 254 children with viral diseases, including measles, varicella, rubella, mumps, echo-30 meningitis, chronic hepatitis B and C, and in eight with Kawasaki disease. Latex agglutination nephelometric immunoassay was used for assaying SAA.
H, Miwata, T, Yamada, M, Okada, T, Kudo, H, Kimura, T, Morishima   +5 more
openaire   +3 more sources

Assessment of the biochemical basis underlying the resistance against systemic amyloidosis [PDF]

Scientific Reports
Amyloid resistance is the reduced or abrogated ability of an organism to develop a specific type of amyloid disease. For example, it was found that certain mouse strains show resistance against systemic AA amyloidosis, due to mutations in the amyloid ...
Tim Moderer, Adrian F. Schnell, Natalie J. Scheurmann, Matthias Schmidt, Christian Haupt, Nadine Schwierz, Marcus Fändrich   +6 more
doaj   +2 more sources