Results 1 to 10 of about 250,870 (304)

RETRACTED: Serum amyloid A protein in the course of infectious mononucleosis

Therapeutic Advances in Infectious Disease, 2019
Serum amyloid A (SAA) protein is a major acute phase protein. Increased concentrations have been reported in many inflammatory diseases. In bacterial infections, high levels correlate with those of C-reactive protein (CRP). In viral infections, where CRP changes are weaker, SAA is of value for establishing early diagnosis, monitoring the severity, and ...
Iliyan Todorov, Margarita Gospodinova, Yana Bocheva, Gergana Popcheva   +3 more
doaj   +4 more sources

Aggregation of Mouse Serum Amyloid A Protein Was Promoted by Amyloid-Enhancing Factors with the More Genetically Homologous Serum Amyloid A. [PDF]

Int J Mol Sci, 2021
Amyloid A (AA) amyloidosis is a condition in which amyloid fibrils characterized by a linear morphology and a cross-β structure accumulate and are deposited extracellularly in organs, resulting in chronic inflammatory diseases and infections. The incidence of AA amyloidosis is high in humans and several animal species.
Lin X, Watanabe K, Kuragano M, Tokuraku K.   +3 more
europepmc   +4 more sources

Serum Amyloid A Protein–Associated Kidney Disease: Presentation, Diagnosis, and Management [PDF]

Kidney Medicine, 2022
Serum amyloid A protein (AA) amyloidosis, also known as secondary amyloidosis, is a known consequence of chronic inflammation and results from several conditions including inflammatory arthritis, periodic fever syndromes, and chronic infection.
Jordan Thorne, David Clark, Laurette Geldenhuys, Keigan More, Amanda Vinson, Karthik Tennankore   +5 more
doaj   +2 more sources

C-reactive protein and serum amyloid A protein as complementary biomarkers in differentiating viral and bacterial community-acquired pneumonia in children [PDF]

BMC Pediatrics
Objective Distinguishing between viral and bacterial community-acquired pneumonia (CAP) in children is crucial for guiding targeted management and antibiotic use.
Juan Cheng, Ying Wu, Hui Ma, Mingyu Tang, Yufen Wu, Yong Yin, Qiuhui Pan, Qizhi Diao, Jing Zhang   +8 more
doaj   +2 more sources

Assessment of the biochemical basis underlying the resistance against systemic amyloidosis [PDF]

Scientific Reports
Amyloid resistance is the reduced or abrogated ability of an organism to develop a specific type of amyloid disease. For example, it was found that certain mouse strains show resistance against systemic AA amyloidosis, due to mutations in the amyloid ...
Tim Moderer, Adrian F. Schnell, Natalie J. Scheurmann, Matthias Schmidt, Christian Haupt, Nadine Schwierz, Marcus Fändrich   +6 more
doaj   +2 more sources

Investigation of acute-phase proteins and cytokines response in goats with contagious caprine pleuropneumonia with special reference to their diagnostic accuracy [PDF]

PeerJ, 2020
Acute-phase proteins (APPs) have always had valued diagnostic potentialities in response to infection. This study aimed to evaluate the diagnostic accuracy of selected APPs and proinflammatory cytokines (PIC) in goats with contagious caprine ...
Wael El-Deeb, Mahmoud Fayez, Ibrahim Elsohaby, Mohamed Salem, Abdulrhman Alhaider, Mahmoud Kandeel   +5 more
doaj   +2 more sources

Revisiting misfolding propensity of serum amyloid A1: Special focus on the signal peptide region

Biochemistry and Biophysics Reports, 2022
AA amyloidosis is the result of overproduction and aberrant processing of acute-phase serum amyloid A1 (SAA1) by hepatocytes. Proteolytic cleavage of SAA1 is believed to play a central role in AA amyloid formation.
Morgan S. Haines, Eduardo Ramirez, Kendall B.E. Moore, Jessica S. Fortin   +3 more
doaj   +1 more source

Presence of a SARS-CoV-2 Protein Enhances Amyloid Formation of Serum Amyloid A [PDF]

The Journal of Physical Chemistry B, 2021
ABSTRACTA marker for the severeness and disease progress of COVID-19 is overexpression of serum amyloid A (SAA) to levels that in other diseases are associated with a risk for SAA amyloidosis. In order to understand whether SAA amyloidosis could also be a long-term risk of SARS-COV-2 infections we have used long all-atom molecular dynamic simulations ...
Asis K. Jana, Augustus B. Greenwood, Ulrich H. E. Hansmann   +2 more
openaire   +4 more sources

Serum amyloid A levels in acute and chronic urticaria [PDF]

Anais Brasileiros de Dermatologia, 2019
: Background: Serum amyloid A is an acute-phase protein. There is no available data regarding serum amyloid A levels in patients with acute (AU) and chronic urticaria (CU). Objective: To investigate the association between serum amyloid A and urticaria.
Wei Lu, Baobing Chen, Chunfeng Wang, Xiaohong Yang, Changyu Zhou   +4 more
doaj   +2 more sources

Serum amyloid A is a better predictive biomarker of mucosal healing than C-reactive protein in ulcerative colitis in clinical remission

BMC Gastroenterology, 2020
Background Many studies have revealed that mucosal healing improves the long-term prognosis of ulcerative colitis. Frequent colonoscopy is difficult because of its invasiveness and cost.
Masaki Wakai, Ryohei Hayashi, Shinji Tanaka, Toshikatsu Naito, Junko Kumada, Motonobu Nomura, Hidehiko Takigawa, Shiro Oka, Yoshitaka Ueno, Masanori Ito, Kazuaki Chayama   +10 more
doaj   +1 more source