Results 41 to 50 of about 250,870 (304)

The acute phase protein serum amyloid A primes neutrophils [PDF]

FEMS Immunology & Medical Microbiology, 2003
We studied here the effect of the acute phase protein serum amyloid A (SAA) on the oxidative burst of neutrophils. Incubation of neutrophils with SAA increased the rate of oxygen uptake and the production of reactive oxygen species of neutrophils activated with opsonized zymosan (OZ). The increment in the neutrophil oxidative burst was dependent on SAA
Elaine, Hatanaka, Fernanda, Pereira Ribeiro, Ana, Campa   +2 more
openaire   +2 more sources

Dysregulation of Na+/K+ ATPase by amyloid in APP+PS1 transgenic mice [PDF]

, 2005
BACKGROUND: The pathology of Alzheimer's disease (AD) is comprised of extracellular amyloid plaques, intracellular tau tangles, dystrophic neurites and neurodegeneration. The mechanisms by which these various pathological features arise are under intense
Dickey, Chad A, Freeman, Melissa J, Gordon, Marcia N, Herber, Donna L, Morgan, Dave, Wilcock, Donna M   +5 more
core   +3 more sources

Neuronal human BACE1 knock-in induces systemic diabetes in mice [PDF]

, 2016
Acknowledgements The authors thank S. Tammireddy (Diabetes and Cardiovascular Science, University of the Highlands and Islands, Inverness, UK) for technical support with the lipidomics component. Funding We would like to thank R.
Dekeryte, Ruta, Delibegovic, Mirela, Doherty, Mary K., Koss, David, Mingarelli, Marco, Mody, Nimesh, Platt, Bettina, Pluci??ska, Kaja, Riedel, Gernot, Shearer, Kirsty, Welch, Andy, Whitfield, Phillip, Whitfield, Phillip D.   +12 more
core   +4 more sources

Serum Amyloid A proteins reduce bone mass during mycobacterial infections

Frontiers in Immunology, 2022
AbstractOsteopenia has been associated to several inflammatory conditions, including mycobacterial infections. How mycobacteria cause bone loss remains elusive, but direct bone infection may not be required. Using genetically engineered mice and morphometric, transcriptomic and functional analyses, we found that infection withMycobacterium aviumimpacts
Ana Cordeiro Gomes, Ana Cordeiro Gomes, Daniela Monteiro Sousa, Daniela Monteiro Sousa, Tiago Carvalho Oliveira, Óscar Fonseca, Óscar Fonseca, Ricardo J. Pinto, Ricardo J. Pinto, Ricardo J. Pinto, Diogo Silvério, Diogo Silvério, Ana Isabel Fernandes, Ana Isabel Fernandes, Ana C. Moreira, Ana C. Moreira, Ana C. Moreira, Tânia Silva, Tânia Silva, Maria José Teles, Maria José Teles, Maria José Teles, Luísa Pereira, Luísa Pereira, Margarida Saraiva, Margarida Saraiva, Meriem Lamghari, Meriem Lamghari, Meriem Lamghari, Maria Salomé Gomes, Maria Salomé Gomes   +30 more
openaire   +4 more sources

Survey on Serum Amyloid A and Haptoglobin Concentrations in Normal or Sensitive to Rumen Acidosis Holstein Dairy Cows [PDF]

Iranian Journal of Veterinary Medicine, 2020
BACKGROUND: Diagnosis and prognosis of inflammatory conditions based on acute phase proteins (APPs) level in blood has been exploited for a long time in human medicine and their changes in SARA condition is considered in veterinary medicine. OBJECTIVES:
Ahmad Paidar Rood Moajeni, Samad Lotfollahzadeh, Gholamreza Ghorbani, Mohammad Reza Mokhber Dezfouli, Mir Morteza Moosavi   +4 more
doaj   +1 more source

Apolipoprotein E related Co-Morbidities and Alzheimer’s disease [PDF]

, 2016
The primary goal of advancement in clinical services is to provide a health care system that enhances an individual’s quality of life. Incidence of diabetes mellitus, cardiovascular disease and associated dementia coupled with the advancing age of the ...
Akiyama, Alharbi, Armitage, Armitage, Armitage, Balin, Barbieri, Bergdahl, Berliner, Borilova Linhartova, Borrell-Pages, Bowling, Braak, Braak, Brown, Bu, Buchanan, Burt, Cambell, Cavrini, Chiu, Chukkapalli, Chukkapalli, Chukkapalli, Cole, Corder, Corrada, Curtiss, Cutler, De Oliveira, DeFronzo, DeStefano, Desvarieux, Duarte, Epel, Farrer, Forner, Foster, Freitag-Wolf, Galbraith, Gan, Gao, Genco, Grehan, Grossi, Habib, Haffajee, Hajishengalis, Hajishengalis, Haraszthy, Hardardottir, Hardy, Harold, Harper, Hayashi, Hayden, Heiduschka, Helfand, Het, Hitt, Holt, Hu, Huang, Hunter, Hutton, Imhof, Iqbal, Itzhaki, Jagannathachary, Joiner, Kamer, Kamer, Kamer, Katz, Khovidhunkit, Klein, Kliegel, Kolovou, Kornman, Kozarov, Kubota, Lalla, Lambert, Lesne, Leszcynska, Libby, Machado, Mahley, Mahley, Mahley, Mahley, Maney, Marti, McGeer, Michalowicz, Miklossy, Miklossy, Miller, Mooradian, Moutsopoulos, Nagpal, Neto, Nicoll, Noble, Okuda, Olsen, Ono, O’Brien, Papapanou, Perls, Pitas, Pizzo, Poirier, Poling, Poole, Poole, Rivera, Riviere, Rogers, Rohn, Roses, Roses, Rowe, Saito, Saunders, Scannapieco, Schuett, Shao, Singhrao, Singhrao, Singhrao, Singhrao, Small, Smit, Socransky, Soscia, Stein, Strittmatter, Strittmatter, Sullivan, Velsko, Walsh, Walsh, Watkins, Weisgraber, Wetterau, Wilson, Young   +147 more
core   +1 more source

Amyloid-β acts as a regulator of neurotransmitter release disrupting the interaction between synaptophysin and VAMP2. [PDF]

, 2012
BACKGROUND: It is becoming increasingly evident that deficits in the cortex and hippocampus at early stages of dementia in Alzheimer's disease (AD) are associated with synaptic damage caused by oligomers of the toxic amyloid-β peptide (Aβ42).
Alifragis, P, Austen, BM, Beesley, PW, Empson, RM, Russell, CL, Semerdjieva, S   +5 more
core   +7 more sources

Usefulness of Measuring Serum Amyloid A Concentration in Japanese Black Cattle in Clinical Practice

Veterinary Sciences, 2023
This study investigated the concentration of serum amyloid A (SAA), an acute phase protein, in Japanese Black cattle. Four practical trials were performed to evaluate the transition of SAA and sialic acid before and after dehorning, the relationship ...
Urara Shinya, Osamu Yamato, Yuka Iwamura, Tomohiro Kato, Yuhei Hamada, Oky Setyo Widodo, Masayasu Taniguchi, Mitsuhiro Takagi   +7 more
doaj   +1 more source

Herpes simplex virus interferes with amyloid precursor protein processing [PDF]

, 2005
Background The early events underlying Alzheimer's disease (AD) remain uncertain, although environmental factors may be involved. Work in this laboratory has shown that the combination of herpes simplex virus type 1 (HSV1) in brain and carriage of the
Dobson, C.B., Itzhaki, R.F., Parkin, E.T., Shipley, S.J.   +3 more
core   +4 more sources

Evaluation of monocyte to HDL cholesterol ratio and other inflammatory markers in patients with psoriasis, [PDF]

Anais Brasileiros de Dermatologia, 2020
Background Psoriasis is a chronic systemic inflammatory disease frequently associated with serious comorbidities. Objectives To investigate the systemic inflammatory burden in psoriasis and to assess the correlation between traditional and novel ...
Mumtaz Cem Sirin, Selma Korkmaz, Ijlal Erturan, Basak Filiz, Buket Cicioglu Aridogan, Emel Sesli Cetin, Mehmet Yildirim   +6 more
doaj   +1 more source