Acceleration of amyloid fibril formation by multichannel sonochemical reactor [PDF]
Formation of amyloid fibrils of various amyloidogenic proteins is dramatically enhanced by ultrasound irradiation. For applying this phenomenon to the study of protein aggregation science and diagnosis of neurodegenerative diseases, a multichannel ultrasound irradiation system with individually adjustable ultrasound-irradiation conditions is necessary.
arxiv +1 more source
The effect of robenacoxib on the concentration of C-reactive protein in synovial fluid from dogs with osteoarthritis [PDF]
Background: Robenacoxib is a novel and highly selective inhibitor of COX-2 in dogs and cats and because of its acidic nature is regarded as being tissue-selective.
Bennett, David+6 more
core +2 more sources
Background: Role of serum amyloid A (SAA) protein as a biomarker for the disease activity in juvenile idiopathic arthritis (JIA) has not been explored. This study was done to find its role as marker of disease activity in JIA.
Sharad Dev, Anup Singh
doaj +1 more source
Regulation of serum amyloid A protein expression during the acute-phase response.
The acute-phase (AP) serum amyloid A proteins (A-SAA) are multifunctional apolipoproteins which are involved in cholesterol transport and metabolism, and in modulating numerous immunological responses during inflammation and the AP response to infection,
L. Jensen, A. Whitehead
semanticscholar +1 more source
Reduction in BACE1 decreases body weight, protects against diet-induced obesity and enhances insulin sensitivity in mice [PDF]
Insulin resistance and impaired glucose homoeostasis are important indicators of Type 2 diabetes and are early risk factors of AD (Alzheimer's disease).
Alex J. Harper+62 more
core +4 more sources
Survey on Serum Amyloid A and Haptoglobin Concentrations in Normal or Sensitive to Rumen Acidosis Holstein Dairy Cows [PDF]
BACKGROUND: Diagnosis and prognosis of inflammatory conditions based on acute phase proteins (APPs) level in blood has been exploited for a long time in human medicine and their changes in SARA condition is considered in veterinary medicine. OBJECTIVES:
Ahmad Paidar Rood Moajeni+4 more
doaj +1 more source
Degradation of serum amyloid A protein by surface-associated enzymes of human blood monocytes
Peripheral blood monocytes incubated in a serum-free medium degraded serum amyloid A (SAA) protein along three pathways. Of 20 normal subjects, 8 degraded SAA completely with no detectable intermediates.
G. Lavie+2 more
semanticscholar +1 more source
Nonsteroidal Anti-Inflammatory Drugs and Ectodomain Shedding of the Amyloid Precursor Protein [PDF]
Background: Epidemiological studies have suggested that long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with a reduced incidence of Alzheimer's disease (AD).
Czirr, Eva+8 more
core +1 more source
Induction of hepatic synthesis of serum amyloid A protein and actin.
Major changes in the mRNA population of murine liver occur after administration of bacterial lipopolysaccharide, an agent that causes increases in the concentrations of acute-phase serum proteins.
John Morrow+3 more
semanticscholar +1 more source
Usefulness of Measuring Serum Amyloid A Concentration in Japanese Black Cattle in Clinical Practice
This study investigated the concentration of serum amyloid A (SAA), an acute phase protein, in Japanese Black cattle. Four practical trials were performed to evaluate the transition of SAA and sialic acid before and after dehorning, the relationship ...
Urara Shinya+7 more
doaj +1 more source