Association between Serum Amyloid A Levels and Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis [PDF]
Background To date, consistent data have not been reported on the association between serum amyloid A (SAA) levels and type 2 diabetes mellitus (T2DM). The purpose of this study was to systematically summarize their relationship.
Ting Liu+3 more
doaj +1 more source
Serum heart-type fatty acid-binding protein and cerebrospinal fluid tau: Marker candidates for dementia with Lewy bodies [PDF]
Background: The measurement of biomarkers in cerebrospinal fluid (CSF) has gained increasing acceptance in establishing the diagnosis of some neurodegenerative diseases.
Andreasen N+27 more
core +1 more source
Succinct Amyloid and Non-Amyloid Patterns in Hexapeptides [PDF]
Hexapeptides are widely applied as a model system for studying amyloid-forming properties of polypeptides, including proteins. Recently, large experimental databases have become publicly available with amyloidogenic labels. Using these datasets for training and testing purposes, one may build artificial intelligence (AI)-based classifiers for ...
arxiv
Neuronal human BACE1 knock-in induces systemic diabetes in mice [PDF]
Acknowledgements The authors thank S. Tammireddy (Diabetes and Cardiovascular Science, University of the Highlands and Islands, Inverness, UK) for technical support with the lipidomics component. Funding We would like to thank R.
Dekeryte, Ruta+12 more
core +3 more sources
Calcium in the initiation, progression and as an effector of Alzheimer's disease pathology. [PDF]
The cause(s) of sporadic Alzheimer's disease (sAD) are complex and currently poorly understood. They likely result from a combination of genetic, environmental, proteomic and lipidomic factors that crucially occur only in the aged brain.
Green, Kim N
core +1 more source
Background Early detection of Rhodococcus equi pneumonia in foals is essential for horse health and for veterinarians. Objectives This study aimed to demonstrate the usefulness of assessing the serum concentration of acute‐phase proteins (APPs) in the ...
Ali Hassanpour, Sina Moghaddam
doaj +1 more source
Functionalization and Characterization of Magnetic Nanoparticles for the Detection of Ferritin Accumulation in Alzheimer's Disease [PDF]
Early diagnosis in Alzheimer's disease (AD), prior to the appearance of marked clinical symptoms, is critical to prevent irreversible neuronal damage and neural malfunction that lead to dementia and death.
Cussó, Lorena+4 more
core +1 more source
Evolution of the Serum Amyloid A (SAA) Protein Superfamily
The serum amyloid A (SAA) superfamily comprises a number of genes and proteins characterized from a range of mammalian species. The majority of members described to date are dramatically induced during the acute-phase response, suggesting an important short-term beneficial role in the response to tissue injury and inflammation.
Alexander S. Whitehead+3 more
openaire +3 more sources
Clinical value of combined detection of SAA,PCT and hs-CRP in predicting neonatal septicemia [PDF]
Objective To study the performance of serum amyloid A (SAA), procalcitonin (PCT) and hypersensitive C-reactive protein (hs-CRP) in predicting and evaluating therapeutic efficacy of neonatal septicemia.
LU Jiali, WU Yunlu
doaj +1 more source
BACKGROUND C-Reactive protein (CRP) and serum amyloid A protein (SAA) are exquisitely sensitive acute-phase reactants, but their baseline values are surprisingly constant in individuals in the general population.
A. MacGregor+3 more
semanticscholar +1 more source