Results 71 to 80 of about 2,828,019 (403)
The effects of peripheral and central high insulin on brain insulin signaling and amyloid-β in young and old APP/PS1 mice [PDF]
, 2016 Hyperinsulinemia is a risk factor for late-onset Alzheimer's disease (AD). In vitro experiments describe potential connections between insulin, insulin signaling, and amyloid-β (Aβ), but in vivo experiments are needed to validate these relationships ...
Caesar, Emily E +9 more
core +2 more sources
Therapeutic Benefits of Tocilizumab Vary in Different Organs of a Patient with AA Amyloidosis
Case Reports in Nephrology, 2014 Systemic reactive AA amyloidosis is a life-threatening complication of chronic inflammatory diseases. Anti-interleukin-6 receptor, tocilizumab (TCZ), has been shown to improve clinical symptoms of patients with AA amyloidosis, accompanied with regression
Masaru Matsui +11 more
doaj +1 more source
Evaluation of monocyte to HDL cholesterol ratio and other inflammatory markers in patients with psoriasis, [PDF]
Anais Brasileiros de Dermatologia, 2020 Background Psoriasis is a chronic systemic inflammatory disease frequently associated with serious comorbidities. Objectives To investigate the systemic inflammatory burden in psoriasis and to assess the correlation between traditional and novel ...
Mumtaz Cem Sirin +6 more
doaj +1 more source
Optimal combinations of acute phase proteins for detecting infectious disease in pigs [PDF]
, 2011 Peer reviewedPublisher ...
Campbell, Fiona Margaret +9 more
core +4 more sources
Inhibiting amyloid-like aggregation through bio-conjugation of proteins with polymer surfactant [PDF]
arXiv, 2020 Prevention of protein aggregation and thus stabilization of proteins has large biological and biotechnological implications. Here, we show that inhibition of amyloid-like aggregates is possible in stoichiometric conjugates of polymer surfactant and bovine serum albumin (BSA) chosen as a model protein.
arxiv
Molecular Oncology, EarlyView.Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever +1 more
wiley +1 more source
Evaluation of acute phase proteins in cows affected by Traumatic Reticuloperitonitis [PDF]
Āsīb/shināsī-i Darmāngāhī-i Dāmpizishkī, 2008 Traumatic Reticuloperitonitis is one of the most important diseases of the bovine digestive system which if diagnosed in early stage and before severe adhesions develop, more effective treatments leading to better prognosis could be under taken.
Ali Rezaei +2 more
doaj
FEBS Open Bio, EarlyView.Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal +2 more
wiley +1 more source
The relationships between vitamin K and cognition: a review of current evidence [PDF]
, 2019 Vitamin K is a fat-soluble nutrient discovered in 1935 and its role in blood coagulation has been thoroughly explored. In recent years, studies conducted in vitro and on animals highlighted vitamin K involvement in brain cells development and survival ...
Alisi, Ludovico +7 more
core +2 more sources
Role of Ligand Conformation on Nanoparticle-Protein Interactions [PDF]
, 2019 Engineered biomedical nanoparticles (NP) administered via intravenous routes are prone to associate to serum proteins. The protein corona can mask the NP surface functionalization and hamper the delivery of the NP to its biological target. The design of corona-free NPs relies on our understanding of the chemical-physical features of the NP surface ...
arxiv +1 more source