Results 51 to 60 of about 16,115 (161)

Human Prostate Cell Lines: Derivation, Molecular Characteristics and Appropriate Use

The Prostate, EarlyView.
ABSTRACT Background Research on prostate cancer and benign prostatic hyperplasia depends on a small number of immortalized human cell lines established between 1977 and 2001, most of them from advanced metastatic disease. The cell lines differ from one another in androgen receptor status, prostate‐specific antigen secretion, p53 status, karyotype and ...
Hamza Abohamra, Keenau Mark Pearce
wiley   +1 more source

Urinary Soluble Collagen Levels Are Associated With Moderate/Severe LUTS

The Prostate, EarlyView.
ABSTRACT Background Expansion of the stromal compartment of the prostate concurrent with fibroblast activation and increased collagenization is now recognized as a pathobiology likely contributing to Lower Urinary Tract Symptoms (LUTS). However, approaches to quantitatively and, ideally, non‐invasively, assess prostatic collagenization in vivo are not ...
Marissa Sarna‐McCarthy, Claweens Quetant, Quentin D'Arcy, Richard Caesar, Kourosh Zarringhalam, Jill A. Macoska   +5 more
wiley   +1 more source

Umbilical Cord Mesenchymal Stem Cells Attenuate Podocyte Injury in Diabetic Nephropathy Rats by Inhibiting Angpltl4/Integrin β3 in the Glomerulus

Journal of Diabetes Research
In this study, we investigated the therapeutic effects and mechanisms of umbilical cord mesenchymal stem cells (UCMSCs) in diabetic nephropathy (DN) ZDF (FA/FA) rats.
Shiyuan Liu, Mingyao Meng, Chunkai Huang, Lijia He, Pu Wang, Zhe Tang, Xi Ran, Hui Gao, Yangfan Guo, Yan He, Jian Chen, Haiyan Hu, Shan He, Yiyi Zhao, Zongliu Hou, Lin Li, Wenhong Li, Wenju Wang, Xiaodan Wang   +18 more
doaj   +1 more source

Ruta graveolens L. in Evidence‐Based Phytotherapy: Pharmacological Activities, Bioactive Compounds and Safety

Phytotherapy Research, EarlyView.
Graphical representation of ethnomedical uses, major bioactive compounds, pharmacological potential and toxicological risks of Ruta graveolens L. ABSTRACT Ruta graveolens L. is widely used in traditional European, Asian, African, and South American medicine for digestive, nervous, cardiovascular, respiratory, and reproductive disorders.
Tetiana Serhiienko, Victoriya Georgiyants, Liudas Ivanauskas, Olha Mykhailenko   +3 more
wiley   +1 more source

小児期における血漿Fibronectinの動態に関する研究 : 第3報 特発性ネフローゼ症候群における血漿Fibronectin値の検討 [PDF]

Plasma fibronectin (p-FN) concentrations of patients with idiopathic nephrotic syndrome (INS) were measured successively to examine correlations with progression of the illness.
128395, 押阪, 裕之
core   +1 more source

Bioactive Gold Plasmonic Interfaces Meet Artificial Intelligence: Advancing Saliva‐Based Surface‐Enhanced Raman Spectroscopy Diagnostics

Small, EarlyView.
ABSTRACT Bioactive gold plasmonic nanostructures are enabling non‐invasive saliva diagnostics by amplifying weak Raman signals and converting complex biofluid chemistry into information‐rich spectral fingerprints. This Review examines saliva‐based Raman and surface‐enhanced Raman spectroscopy (SERS) integrated with artificial intelligence (AI) from a ...
Ajitesh Dhal, Ana Elena Aviña, Nguyen Le Thanh Hang, Pei‐Wen Peng, Cheng‐Jen Chang, Tzu‐Sen Yang   +5 more
wiley   +1 more source

Magnesium lithospermate B improves renal hemodynamics and reduces renal oxygen consumption in 5/6th renal ablation/infarction rats

BMC Nephrology, 2019
Background Magnesium lithospermate B (MLB) can promote renal microcirculation. The aim of the current project was to study whether MLB improves renal hemodynamics, oxygen consumption and subsequently attenuates hypoxia in rats induced by 5/6th renal ...
Pinglan Lin, Ming Wu, Junyan Qin, Jing Yang, Chaoyang Ye, Chen Wang   +5 more
doaj   +1 more source

Nonthermal plasma approaches for combating implant‐associated infections: A compendious review

VIEW, EarlyView.
Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe, Satish Rojekar, Amol Gholap, K. Navaneetha Pandiyaraj, Mukesh Patekar, Claudia Riccardi, R. R. Deshmukh, Tomáš Kovářík, Kalim Deshmukh   +8 more
wiley   +1 more source

Extracellular vesicles in pharmacology: Innovations in drug delivery and therapeutic applications in cancer

British Journal of Pharmacology, EarlyView.
Extracellular vesicles (EVs) are a diverse population of membrane nanoparticles secreted by nearly all cell types, playing a key role in intercellular communication by transferring bioactive macromolecular cargo. In cancer, EVs shape both the local tumour microenvironment and distant premetastatic niches.
Evangelia Pantazaka, Georgios Sivvas, Evangelia Papadimitriou, Constantinos M. Mikelis   +3 more
wiley   +1 more source

Genetic Testing Unveils a Novel Thrombospondin‐1 Domain Containing Protein 1 Gene Variant as the Cause of Chronic Edema in a 79‐Year‐Old Woman

Clinical Genetics, EarlyView.
A 79‐year‐old woman with lifelong peripheral edema and an affected sister was found to harbor a novel homozygous THSD1 splice‐site variant. Reduced THSD1 expression in dermal endothelial cells supported the possibility that this variant contributes to chronic hereditary edema.
Eiko Amo, Takafumi Toyohara, Naoya Saijo, Satoko Sato, Jun Takayama, Yoshiko Suto, Yuji Noguchi, Sosuke Kinomura, Yusuke Ishizuka, Shun Watanabe, Koichi Kikuchi, Rui Makino, Mai Yoshida, Yuji Oe, Tasuku Nagasawa, Koji Okamoto, Takehiro Suzuki, Mariko Miyazaki, Shinya Kawaguchi, Takashi Suzuki, Takaaki Abe, Shigeo Kure, Atsuo Kikuchi, Tetsuhiro Tanaka   +23 more
wiley   +1 more source