Respiratory syncytial virus (RSV) is a highly contagious human pathogen that poses a significant threat to children under the age of two, and there is a current need for new small molecule treatments. The Antarctic sponge Suberites sp.
Joe Bracegirdle +6 more
doaj +1 more source
9-Deoxymuzigadial, a Sesquiterpene Isolated From Drimys brasiliensis (Winteraceae), Displays Reduced Cytotoxicity In Vitro and Modulates Leukocyte Activity and Fibrogenesis In Vivo. [PDF]
ABSTRACT The aims of this study were to investigate in vitro cytotoxic potential and the effects of daily administration during the inflammatory response induced by sponge implants in mice of the sesquiterpene 9‐deoxymuzigadial (9‐DOM), isolated from Drimys brasiliensis (Winteraceae).
Ferreira BA +7 more
europepmc +2 more sources
Chemical investigation of a biologically active schinus molle L. leaf extract [PDF]
The pepper tree Schinus molle L. is an evergreen ornamental plant belonging to the Anacardiaceae family, native to South America and widespread throughout the world. It has biological activities and is used in folk medicine. This paper aims to contribute
Garzoli, S. +5 more
core +1 more source
Thiophene Derivatives as Versatile Precursors for (Hetero)Arene and Natural Product Synthesis
Hidden but Powerful: Thiophenes and their saturated analogues have been demonstrated to be versatile C4‐building blocks that can be rapidly applied to natural product synthesis and the construction of functionalized (hetero)arenes. This minireview aims to provide a concise overview of the strategies and implementations of these sulfur‐containing ...
Anna Keimer, Franz‐Lucas Haut
wiley +1 more source
Ozone stress as a driving force of sesquiterpene emissions: a suggested parameterization [Discussion paper] [PDF]
Sesquiterpenes (C15H24) are semi-volatile organic compounds emitted by vegetation and are of interest in atmospheric research because they influence the oxidative capacity of the atmosphere and contribute to the formation of secondary organic aerosols ...
Bonn, Boris +5 more
core +1 more source
Citrus aroma and flavor, chief traits of fruit quality, are derived from their high content in essential oils of most plant tissues, including leaves, stems, flowers, and fruits.
Berta Alquézar +6 more
doaj +1 more source
In Vitro Anti-Influenza A Virus H1N1 Effect of Sesquiterpene-Rich Extracts of Carpesium abrotanoides
Due to a high content of sesquiterpenes, Carpesium abrotanoides has been investigated to fully explore its health-promoting properties. Therefore, this work aimed to assess, for the first time, the anti-influenza A virus H1N1 potential of sesquiterpene ...
Li Li +7 more
doaj +1 more source
Secondary Organic Aerosol Formation from Healthy and Aphid-Stressed Scots Pine Emissions. [PDF]
One barrier to predicting biogenic secondary organic aerosol (SOA) formation in a changing climate can be attributed to the complex nature of plant volatile emissions.
Buchholz, Angela +11 more
core
Directed enzyme evolution: climbing fitness peaks one amino acid at a time [PDF]
Directed evolution can generate a remarkable range of new enzyme properties. Alternate substrate specificities and reaction selectivities are readily accessible in enzymes from families that are naturally functionally diverse.
Arnold, Frances H., Tracewell, Cara A.
core +2 more sources
Abstract Guaraná (Paullinia cupana) is a fruit native to the Amazon region. Due to its widespread use, primarily in beverages, its production has grown over the years. The seed is the only commercially valuable part of the fruit so the guaraná production chain generates byproducts, including peel, husk, and spent seed.
Leiliane do Socorro Sodré de Souza +9 more
wiley +1 more source

