Results 121 to 130 of about 3,688,287 (401)

Remotely Monitored Therapy and Nitric Oxide Suppression Identifies Nonadherence in Severe Asthma

American Journal of Respiratory and Critical Care Medicine, 2019
Rationale: Poor adherence is common in difficult‐to‐control asthma. Distinguishing patients with difficult‐to‐control asthma who respond to inhaled corticosteroids (ICS) from refractory asthma is an important clinical challenge.
L. Heaney, J. Busby, P. Bradding, R. Chaudhuri, A. Mansur, R. Niven, I. Pavord, John T Lindsay, R. Costello   +8 more
semanticscholar   +1 more source

Sex Differences in Severe Asthma: Results From Severe Asthma Network in Italy-SANI

Allergy Asthma and Immunology Research, 2020
Purpose After adolescence, asthma is more frequent in females than in males due to different hormonal, immunologic, and occupational/environmental factors.
G. Senna, M. Latorre, Massimo Bugiani, M. Caminati, E. Heffler, Daniela Morrone, G. Paoletti, P. Parronchi, F. Puggioni, F. Blasi, G. Canonica, P. Paggiaro   +11 more
semanticscholar   +1 more source

OTUD6A in Airway Epithelial Cells Exacerbates Allergic Asthma by Promoting Airway Inflammation and Airway Remodeling Through Deubiquitination of hResistin/mRELMα

Advanced Science, EarlyView.
This study elucidates a novel mechanistic role of the deubiquitinase OTUD6A in asthma pathogenesis, uncovering its regulatory function in airway inflammation and airway remodeling through the stabilization of hResistin/mRELMα. This study offers a novel regulatory axis (OTUD6A‐hResistin/mRELMα) in asthma pathogenesis and OTUD6A inhibition as a potential
Weiting Pan, Xinru Xi, Wei Dai, Tingfang Xiao, Yeqing Chen, Xuanyu Chen, Xiangting Ge, Chengguang Zhao, Hui Zhang, Yali Zhang, Weixi Zhang   +10 more
wiley   +1 more source

Estadsticas del Asma en Los Latinos [PDF]

, 2009
Chicago is known for many things, our great food and architecture. Unfortunately, we are also known for being an epi-center for asthma. We lead the Nation in asthma deaths, emergency room visits and hospitalizations.

core  

Asthma referrals : a key component of asthma management that needs to be addressed [PDF]

, 2017
Peer reviewedPublisher ...
Bergen, David A, Bjermer, Leif, Martinez, Rafael, Price, David   +3 more
core   +1 more source

Biologic Therapies for Severe Asthma.

New England Journal of Medicine, 2022
G. Brusselle, G. Koppelman
semanticscholar   +1 more source

Targeting NLRP3 Inflammasome Activation in Severe Asthma

Journal of Clinical Medicine, 2019
Severe asthma (SA) is a chronic lung disease characterized by recurring symptoms of reversible airflow obstruction, airway hyper-responsiveness (AHR), and inflammation that is resistant to currently employed treatments.
Efthymia Theofani, M. Semitekolou, I. Morianos, K. Samitas, G. Xanthou   +4 more
semanticscholar   +1 more source

Boron Nitride Nanomaterials Trigger Immunomodulatory Effects in Human Broncho‐Epithelial Cells by Modulating Eicosanoid Lipid Signaling

Advanced Science, EarlyView.
This study demonstrates that BNNT exposure disrupts lipid homeostasis in bronchial epithelial cell cultures and activates eicosanoid lipid biosynthesis, producing inflammatory lipid mediators like leukotrienes. These effects are more pronounced in asthmatic cell cultures compared to healthy ones.
Govind Gupta, Jonas Bossart, Sènan Mickael D'Almeida, Luis Augusto Visani de Luna, Christoph Schwärzler, Tingting Fu, Vanesa Ayala‐Nunez, Alexander Gogos, Marija Buljan, Vera M Kissling, Emmanuel Flahaut, Miguel Garcia, Cyrill Bussy, Peter Wick, Tina Buerki‐Thurnherr   +14 more
wiley   +1 more source

Asthma Is More Severe in Older Adults.

PLoS ONE, 2015
BackgroundSevere asthma occurs more often in older adult patients. We hypothesized that the greater risk for severe asthma in older individuals is due to aging, and is independent of asthma duration.MethodsThis is a cross-sectional study of prospectively
Joe G Zein, Raed A Dweik, Suzy A Comhair, Eugene R Bleecker, Wendy C Moore, Stephen P Peters, William W Busse, Nizar N Jarjour, William J Calhoun, Mario Castro, K Fan Chung, Anne Fitzpatrick, Elliot Israel, W Gerald Teague, Sally E Wenzel, Thomas E Love, Benjamin M Gaston, Serpil C Erzurum, Severe Asthma Research Program   +18 more
doaj   +1 more source

Efficacy of azithromycin in severe asthma from the AMAZES randomised trial

ERJ Open Research, 2019
Background Low-dose azithromycin is an effective therapy for persistent asthma; however, its benefit in severe asthma is not defined. Methods Participants with severe asthma were identified from the AMAZES randomised, placebo-controlled trial of long ...
Peter G. Gibson, Ian A. Yang, John W. Upham, Paul N. Reynolds, Sandra Hodge, Alan L. James, Christine Jenkins, Matthew J. Peters, Guy B. Marks, Melissa Baraket, Heather Powell, Jodie L. Simpson   +11 more
doaj   +1 more source