Results 151 to 160 of about 3,446,938 (405)

Neutrophil cytoplasts induce TH17 differentiation and skew inflammation toward neutrophilia in severe asthma

open access: yesScience immunology, 2018
Neutrophil cytoplasts promote TH17 inflammation. Nefarious neutrophil cytoplasts In addition to DNA release, neutrophil extracellular trap (NET) formation can result in enucleated cells called cytoplasts. Krishnamoorthy et al.
N. Krishnamoorthy   +22 more
semanticscholar   +1 more source

Beyond Climate Change Concern: Why Air Pollution Health Concern and Health Orientation Matter in Battery Electric Vehicle Adoption

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT While previous research has emphasized climate change concern as a driver of battery electric vehicle (BEV) adoption, concerns about the personal health impacts of air pollution caused by internal combustion vehicles—such as respiratory and cardiovascular diseases—have been neglected as behavioral triggers.
Patrick Hartmann   +4 more
wiley   +1 more source

Omalizumab as alternative to chronic use of oral corticosteroids in severe asthma

open access: yes, 2019
Systemic/oral corticosteroids (OCS) have been used for decades in the management of acute asthma exacerbations and chronically in patients with uncontrolled severe asthma.
Bousquet, Jean   +6 more
core   +1 more source

The Correlation between Atopy Level and Asthma Manifestation in Children 3-10 Years of Age at The Pulmonary Community Health Center (Bbkpm) Surakarta, Central Java [PDF]

open access: yes, 2018
Background: Asthma is a chronic inflammation of the airways that involves many cells and their elements. In Indonesia, the incidence of asthma in children ranges from 2 to 30% and it causes the loss of child’s school days.
Rahayuningrum, I. O. (Indriyati)   +2 more
core   +1 more source

Nordic consensus statement on the systematic assessment and management of possible severe asthma in adults

open access: yesEuropean Clinical Respiratory Journal, 2018
Although a minority of asthma patients suffer from severe asthma, they represent a major clinical challenge in terms of poor symptom control despite high-dose treatment, risk of exacerbations, and side effects.
Celeste Porsbjerg   +17 more
doaj   +1 more source

Dupilumab Efficacy and Safety in Moderate‐to‐Severe Uncontrolled Asthma

open access: yesNew England Journal of Medicine, 2018
BACKGROUND Dupilumab is a fully human anti–interleukin‐4 receptor α monoclonal antibody that blocks both interleukin‐4 and interleukin‐13 signaling. We assessed its efficacy and safety in patients with uncontrolled asthma.
M. Castro   +26 more
semanticscholar   +1 more source

Pareto in Prison

open access: yesBehavioral Sciences &the Law, EarlyView.
ABSTRACT The Pareto principle is based on the concept that roughly 80% of outcomes are generated by 20% of inputs, efforts, or contributors within a group. Using a national sample of U.S. prison inmates, we examined various percentile rankings of self‐reported institutional misconduct to determine how much disorder is created behind bars by the most ...
Mark A. Morgan   +3 more
wiley   +1 more source

Assessing severe asthma [PDF]

open access: yesEuropean Respiratory Journal, 2016
Structured assessment of patients identifies asthma misdiagnosis, and improves asthma control and quality of life http://ow.ly ...
openaire   +2 more sources

Assessment of asthma control and asthma exacerbations in the epidemiology and natural history of asthma: outcomes and treatment regimens (TENOR) observational cohort [PDF]

open access: yes, 2012
Patients with severe or difficult-to-treat asthma account for substantial asthma morbidity, mortality, and healthcare burden despite comprising only a small proportion of the total asthma population.
Alejandro Dorenbaum   +12 more
core   +2 more sources

Oral corticosteroid-sparing effects of reslizumab in the treatment of eosinophilic granulomatosis with polyangiitis

open access: yesERJ Open Research, 2020
Brian D. Kent   +9 more
doaj   +1 more source

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