Results 151 to 160 of about 3,688,287 (401)

Severe Asthma and Biological Therapy: When, Which, and for Whom

Pulmonary Therapy, 2019
Asthma is a heterogeneous chronic inflammatory disease of the airways that affects approximately 300 million people worldwide. About 5–10% of all asthmatics suffer from severe or uncontrolled asthma, associated with increased mortality and ...
P. Rogliani, L. Calzetta, M. Matera, R. Laitano, B. L. Ritondo, N. Hanania, M. Cazzola   +6 more
semanticscholar   +1 more source

Acute Exercise Challenge and Airway Dynamics in Youth With Sickle Cell Anemia: A Multicenter Study

American Journal of Hematology, EarlyView.
Changes in airway dynamics in children with sickle cell anemia after maximal cardiopulmonary exercise testing and a controlled intensity interval excercise challenge. ABSTRACT Sickle cell anemia (SCA) leads to reduced physical functioning and cardiopulmonary fitness. Prior studies suggest that airway hyperresponsiveness to bronchoprovocation testing is
Robyn T. Cohen, Jane S. Hankins, Kirsten K. Ness, Lewis L. Hsu, Tracy Baynard, Amy Tang, Shlomit Radom‐Aizik, Kevin Guerrero, Mark Rodeghier, Robert I. Liem   +9 more
wiley   +1 more source

Steroid-sparing effects of benralizumab in patients with eosinophilic granulomatosis with polyangiitis

ERJ Open Research, 2020
Alexandra M. Nanzer, Jaideep Dhariwal, Joanne Kavanagh, Andrew Hearn, Mariana Fernandes, Louise Thomson, Cris Roxas, Linda Green, Grainne D'Ancona, Sangita Agarwal, Brian D. Kent, David J. Jackson   +11 more
doaj   +1 more source

Mepolizumab and COPD in Real Life

Open Respiratory Archives, 2022
Fernando Revuelta-Salgado, Rocío Magdalena Díaz-Campos, Ascensión Hernando-Sanz, Carlos Melero-Moreno   +3 more
doaj   +1 more source

Nance‐Horan Syndrome: Further Delineation of the Affected Male and the Female Carrier Phenotypes

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Nance‐Horan syndrome (NHS; OMIM 302350) is a rare, X‐linked syndrome characterized by bilateral congenital cataracts leading to profound vision loss, specific dental anomalies including characteristic screwdriver blade‐shaped incisors, facial anomalies, and intellectual disability.
Maria K. Haanpää, Chad R. Haldeman‐Englert, Marja Hietala, Melisa S. Tanverdi, Patrick P. Koty, Diana Brightman, Eniolami Dosunmu, Shailja Tibrewal, Savleen Kaur, Anupriya Kaur, Raj Kumar Verma, Alejandra G. de Alba Campomanes, Virginia Utz, Anne M. Slavotinek, Cynthia Curry   +14 more
wiley   +1 more source

Is it severe asthma or asthma with severe comorbidities?

Journal of Asthma and Allergy, 2017
Luisa Brussino,1 Paolo Solidoro,2 Giovanni Rolla1 1Allergy and Clinical Immunology, University of Torino and Mauriziano Hospital, 2SC Pneumologia U, AOU Città della Salute e della Scienza, Torino, Italy Abstract: Severe asthma is defined as asthma
Brussino L, Solidoro P, Rolla G
doaj  

High Burden of Exacerbations of Severe Asthma: Results from a Real-World Study of Patients Treated by Subspecialists in the United States [PDF]

, 2020
Warner Carr, Njira Lugogo, Wendy C. Moore, Reynold A. Panettieri, Weily Soong, Frank Trudo, Chris Ambrose   +6 more
openalex   +1 more source

Dupilumab Efficacy and Safety in Moderate‐to‐Severe Uncontrolled Asthma

New England Journal of Medicine, 2018
BACKGROUND Dupilumab is a fully human anti–interleukin‐4 receptor α monoclonal antibody that blocks both interleukin‐4 and interleukin‐13 signaling. We assessed its efficacy and safety in patients with uncontrolled asthma.
M. Castro, J. Corren, I. Pavord, J. Maspero, S. Wenzel, K. Rabe, W. Busse, L. Ford, L. Sher, M. Fitzgerald, C. Katelaris, Y. Tohda, Bingzhi Zhang, H. Staudinger, G. Pirozzi, N. Amin, M. Ruddy, B. Akinlade, A. Khan, J. Chao, R. Martincova, N. Graham, J. Hamilton, B. Swanson, N. Stahl, G. Yancopoulos, A. Teper   +26 more
semanticscholar   +1 more source

GATA3 Deletion Associated With Juvenile Idiopathic Arthritis: Expanding the Phenotypic Spectrum of Hypoparathyroidism, Sensorineural Deafness, and Renal Dysplasia (HDR) Syndrome

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Hypoparathyroidism, sensorineural deafness, and renal dysplasia (HDR) syndrome is caused by pathogenic variants in the GATA3 gene located on chromosome 10p14. Here we present a 10‐year‐old girl with HDR syndrome who also has oligoarticular juvenile idiopathic arthritis (JIA).
Lauren N. Meiss, Amanda V. Karam, Julia Shalen, David E. Tunkel, Belina Y. Yi, Kelsey S. Guthrie, Emily M. Kudalkar, Anna E. Patrick, Sonja A. Rasmussen   +8 more
wiley   +1 more source

Oral health-related quality of life in individuals with severe asthma [PDF]

Jornal Brasileiro de Pneumologia
Objective: To evaluate oral health-related quality of life (OHRQoL) among individuals with severe asthma, comparing it with that observed among individuals with mild-to-moderate asthma and individuals without asthma.
Rebeca Brasil-Oliveira, Álvaro Augusto Cruz, Adelmir Souza-Machado, Gabriela Pimentel Pinheiro, Debora dos Santos Inácio, Viviane Almeida Sarmento, Liliane Lins-Kusterer   +6 more
doaj   +4 more sources