Results 101 to 110 of about 19,116 (219)

Frequency and histological appearance of adenomas in multiple intestinal neoplasia mice are unaffected by severe combined immunodeficiency (scid) mutation. [PDF]

, 1996
Well-characterized murine mutations are powerful analytical tools for the genetic analysis of tumorigenesis. We crossed the multiple intestinal neoplasia (Min) allele of adenomatous polyposis coli (Apc), which produces a profound pre-disposition to ...
Dudley, M E, Sundberg, J P, Roopenian, D C   +2 more
core  

Therapeutic potential of spexin in diabetic neuropathy: Insights from in vitro and in vivo models

Experimental Physiology, Volume 111, Issue 8, Page 3800-3817, 1 August 2026.
Abstract The present study investigated the therapeutic potential of spexin (SPX) on both in vitro and in vivo models of diabetic neuropathy (DN). A total of 40 male BALB/c mice were randomly allocated into four experimental groups (n = 10 per group): a normoglycaemic control, an untreated DN group and two SPX treatment groups (DN+SPX‐12.5 and DN+SPX ...
Mehmet Refik Bahar, Seval Ulku Orhan, Cigdem Tekin, Asli Taslidere, Mete Ozcan, Suat Tekin   +5 more
wiley   +1 more source

Testing Methodology and Clinical Advantages of a Newborn Screening Protocol for Severe Combined Immunodeficiency [PDF]

, 2021
Severe combined immunodeficiency (SCID) is a genetic disorder defined by a disruption in the development of functional T cells and B cells that circulate in the body (1).
Ryan, Alicia
core   +1 more source

A high‐fat, high‐sucrose diet exacerbates muscle and metabolic pathology and undermines glucocorticoid efficacy in dystrophin‐deficient mice

The Journal of Physiology, Volume 604, Issue 15, Page 6440-6464, 1 August 2026.
Abstract figure legend A high‐fat, high‐sucrose diet (HFHSD) exacerbated muscle and metabolic dysregulation in mdx mice while also altering the physiological response to prednisolone (Pred) In diaphragms of control diet (CD)‐fed mdx mice, prednisolone treatment improved muscle function and reduced fibrosis, inflammatory signalling, and mitochondrial ...
Morgan E. Vorwald, Swathy Krishna, Ji Heun Lee, Melissa Roths, Rudy J. Valentine, Joshua T. Selsby   +5 more
wiley   +1 more source

Chimerism in a child with severe combined immunodeficiency: a case report [PDF]

, 2006
Severe combined immunodeficiency (SCID) represents a group of rare, sometimes fatal, congenital disorders in which there is a combined absence of T-lymphocyte and B-lymphocyte function. Children with SCID die within two years of age, if untreated.
Aureli, A, Antonina Piazza, Domenico Adorno, ISACCHI, GIANCARLO, Adorno, D., Giancarlo Isacchi, Daniela Piancatelli, Monaco, PI, Caniglia, M, Angelica Canossi, Maurizio Caniglia, Anna Aureli, Isacchi, G, Giuseppina Ozzella, Piazza, A, Adorno, D, Piancatelli, D, Ozzella, G, Canossi, A, Palmina I. Monaco   +19 more
core   +1 more source

Disseminated tuberculosis complicating Bacillus Calmette-Guérin (BCG) vaccine as only presentation of severe combined immunodeficiency (SCID): A report of 3 cases. [PDF]

Qatar Med J, 2023
Omer K, Algaly G, Mohamed Salih OA.
europepmc   +1 more source

The Role of Invasive Procedures in the Treatment of Complicated Gastrointestinal Graft‐Versus‐Host Disease in Pediatric Patients

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Background Gastrointestinal graft‐versus‐host disease (GI GVHD) following hematopoietic stem cell transplant is typically managed with medical therapy, but surgery and angioembolization may be warranted in selected cases with life‐threatening complications.
Gaia Brunetti, Giorgio Persano, Chiara Grimaldi, Pier Luigi Di Paolo, Carmen Malaspina, Francesco Quagliarella, Valerio Balassone, Anna Chiara Iolanda Contini, Gian Luigi Natali, Rita Alaggio, Ivan Pietro Aloi, Tamara Caldaro, Alessandro Crocoli   +12 more
wiley   +1 more source

Stem cell–based therapies for type 1 diabetes: Progress in differentiation, clinical translation, and immune protection

Animal Models and Experimental Medicine, Volume 9, Issue 7, Page 1277-1291, July 2026.
Directed differentiation of pluripotent stem cells into functional pancreatic β cells have emerged as a promising strategy for the radical treatment of type 1 diabetes, with preclinical and early clinical evidence demonstrating reversal of hyperglycemia and insulin independence.
Zifan Li, Yu Kang, Yuyu Niu
wiley   +1 more source

Data in support of the bone analysis of NOD–SCID mice treated with zoledronic acid and prednisolone

Data in Brief, 2016
This paper reports data on the bone, specifically the tibia and mandible, of nonobese diabetic mice with severe combined immunodeficiency disease (NOD–SCID mice) treated with zoledronic acid (ZA) and prednisolone (PSL).
Naoko Hori, Takahiro Abe, Tsuyoshi Sato, Shoichiro Kokabu, Yumiko Shimamura, Tomoya Sato, Tetsuya Yoda   +6 more
doaj   +1 more source

Severe Combined ImmunoDeficient (SCID) mice in biomedical research

Journal of the Hellenic Veterinary Medical Society, 2017
Mice have been used in cancer research since the last decade of the 19th century. In 1921 inbred strains, that were predisposed to developing tumors, were bred and became available to cancer researchers. The nude mouse, a hairless mutantdiscovered in 1962, is immunodeficient, and thus does not reject tumor transplantations from other species.
openaire   +2 more sources