Results 81 to 90 of about 19,116 (219)

Disseminated BCG infection and rotavirus enteritis in an infant with severe immunodeficiency: a causal association study

Frontiers in Public Health
Live attenuated vaccines may cause life-threatening complications in infants with undiagnosed severe combined immunodeficiency (SCID). We describe a fatal case of disseminated Bacillus Calmette–Guérin infection and rotavirus enteritis in an infant with ...
Jianlin Cai, Shuping Li, Jingyi Xu, Zhen Li, Fang Wang, Liqing Yang, Bin Jia, Yunhua Bai, Li Li   +8 more
doaj   +1 more source

The role of acquired host immunity in periodontal diseases

Periodontology 2000, EarlyView.
Abstract The aim of this narrative review is to relate the contribution of European researchers to the complex topic of the host immune system in periodontal disease, focusing on acquired immunity. Other chapters in this volume will address the genetics and autoantibody responses and other forms of immunity to periodontal disease.
Denis F. Kinane, David F. Lappin, Shauna Culshaw   +2 more
wiley   +1 more source

Mitochondrial Ca2+ uniporter haploinsufficiency leads to sexually dimorphic redox imbalance and metabolic remodelling in the mouse brain

The Journal of Physiology, EarlyView.
Abstract figure legend The genetic inactivation of one Mcu allele leads to sex‐specific changes in neuronal function in adult mice, that is, the firing of action potentials and the relationship between cytosolic and mitochondrial Ca2+ levels. The ability to produce NAD(P)H by stimulated neural tissue is largely preserved in male mice but delayed in ...
Jenna Gray, Girish Halemirle, Beatriz Ferrán, Hadyn Rose, Traci L. Redwine, Sophia Pham, Bo Hagy, Atul Pranay, Jennifer Giorgione, Stacy A. Hussong, Veronica Galvan, Kenneth Humphries, Holly Van Remmen, Mike Kinter, William E. Sonntag, Pankaj K. Singh, Carlos Manlio Díaz‐García   +16 more
wiley   +1 more source

New characterization of congenital immunodeficiencies due to different functional alterations [PDF]

, 2010
In the last thirty years of the 20th century, a formidable numbers of scientific discoveries in the field of PIDs were made. Many scientific papers have been published on the molecular and cellular basis of the immune response and on the mechanisms ...
Fusco, Anna
core  

Generation of Allogeneic CAR‐T Circumvents Functional Deficits in Patient‐Derived Autologous Product for Glioblastoma

International Journal of Cancer, Volume 159, Issue 6, Page 1521-1534, 15 September 2026.
Clinical trials of chimeric antigen receptor T‐cell (CAR‐T) therapies in glioblastoma have shown limited clinical benefits. Whether this may be explained by the basal quality of CAR‐T products, which are currently generated using patient, autologous T‐cells, has been little explored.
Sabra K. Salim, Muhammad Vaseem Shaikh, Jeffrey Wei, William T. Maich, Alisha Anand, Oliver Y. Tang, Minomi K. Subapanditha, Zahra Alizada, Yujin Suk, Manoj Singh, Kui Zhai, Aapti Khanna, Benjamin Brakel, Vassil Dimitrov, Zoya Tabunshchyk, Katie Chan, Kevin R. Brown, Parvez Vora, Donald M. O'Rourke, Zev A. Binder, Chitra Venugopal, Jason Moffat, Sheila K. Singh   +22 more
wiley   +1 more source

Dental manifestations in severe combined immunodeficiency following bone marrow transplantation [PDF]

, 2000
Severe combined immunodeficiency (SCID) is a rare primary immunodeficiency disorder with an estimated overall frequency of 1 in 75,000 live births. Bone marrow transplantation is the only curative treatment available.
Welbury RR, Bond E, Abinun M, Cole BOI
core  

Prostate Cancer Development, Progression, and Therapy

MedComm – Oncology, Volume 5, Issue 3, September 2026.
This review provides an integrated overview of prostate cancer development, progression, and therapy, spanning historical milestones, molecular mechanisms, advanced research models, and emerging therapeutic strategies. It highlights recent advances in precision diagnosis, lineage plasticity, therapy resistance, and next‐generation treatments for ...
Xin Jin, Zicheng Xiao, Zexian Ding, Wei Li, Ruijiang Zeng, Yujun Shuai, Weimin Ci, Dan Xia, Xu Zhang, Haojie Huang   +9 more
wiley   +1 more source

Successful Handling of Disseminated BCG Disease in a Child with Severe Combined Immunodeficiency

Case Reports in Medicine, 2011
In high-burden countries, Mycobacterium bovis Bacillus Calmette-Guérin (BCG) vaccine is administered in newborn to prevent severe Mycobacterium tuberculosis infection.
Sílvia Bacalhau, Cristina Freitas, Rosalina Valente, Deolinda Barata, Conceição Neves, Katrin Schäfer, Annelie Lubatschofski, Ansgar Schulz, João Farela Neves   +8 more
doaj   +1 more source

Insights Into the Biological Mechanisms and Multifunctional Health Benefits of Morelloflavone

eFood, Volume 7, Issue 4, August 2026.
Morelloflavone (MF), a biflavonoid from Garcinia and related species, exhibits broad human health benefits through antioxidant, anti‐inflammatory, anticancer, and metabolic regulatory effects. This review highlights its molecular mechanisms, biosynthesis, and emerging roles in chronic disease prevention, emphasizing systems biology and machine learning
Yi Liu, Ziyong Mao, Jesus Simal‐Gandara, Zi Chen, Hui Cao   +4 more
wiley   +1 more source

Delayed presentation of severe combined immunodeficiency due to prolonged maternal T cell engraftment

Annals of Saudi Medicine, 2010
Severe combined immunodeficiency (SCID) is a primary immunodeficiency disorder with heterogenous genetic etiologies. We describe a typical case in a 9-year-old boy that was masked by a clinically functional maternal T cell engraftment leading to late ...
Al-Muhsen Saleh
doaj