Results 11 to 20 of about 45,777 (283)

Severe combined immunodeficiency (SCID) in Canadian children: a national surveillance study. [PDF]

J Clin Immunol, 2013
Severe Combined Immune Deficiency (SCID) is universally fatal unless treated with hematopoietic stem cell transplantation (HSCT). Following the identification of disseminated Bacille Calmette-Guérin (BCG) infections in Canadian First Nations, Métis and ...
Rozmus J, Junker A, Thibodeau ML, Grenier D, Turvey SE, Yacoub W, Embree J, Haddad E, Langley JM, Ramsingh RM, Singh VA, Long R, Schultz KR.   +12 more
europepmc   +5 more sources

A Human Severe Combined Immunodeficiency (SCID) Condition with Increased Sensitivity to Ionizing Radiations and Impaired V(D)J Rearrangements Defines a New DNA Recombination/Repair Deficiency [PDF]

Journal of Experimental Medicine, 1998
The products of recombination activating gene (RAG)1 and RAG2 initiate the lymphoid-specific phase of the V(D)J recombination by creating a DNA double-strand break (dsb), leaving hairpin-sealed coding ends.
Nathalie Nicolas, Despina Moshous, Marina Cavazzana, D. Papadopoulo, Régina de Chasseval, Françoise Le Deist, Alain Fischer, Jean‐Pierre de Villartay   +7 more
openalex   +2 more sources

Ten Years of Newborn Screening for Severe Combined Immunodeficiency (SCID) in Massachusetts. [PDF]

J Allergy Clin Immunol Pract, 2021
Hale JE, Platt CD, Bonilla FA, Hay BN, Sullivan JL, Johnston AM, Pasternack MS, Hesterberg PE, Meissner HC, Cooper ER, Barmettler S, Farmer JR, Fisher D, Walter JE, Yang NJ, Sahai I, Eaton RB, DeMaria A, Notarangelo LD, Pai SY, Comeau AM.   +20 more
europepmc   +2 more sources

When Screening for Severe Combined Immunodeficiency (SCID) with T Cell Receptor Excision Circles Is Not SCID: a Case-Based Review. [PDF]

J Clin Immunol, 2021
Buchbinder D, Walter JE, Butte MJ, Chan WY, Chitty Lopez M, Dimitriades VR, Dorsey MJ, Nugent DJ, Puck JM, Singh J, Collins CA.   +10 more
europepmc   +2 more sources

Disseminated BCG infection and rotavirus enteritis in an infant with severe immunodeficiency: a causal association study [PDF]

Frontiers in Public Health
Live attenuated vaccines may cause life-threatening complications in infants with undiagnosed severe combined immunodeficiency (SCID). We describe a fatal case of disseminated Bacillus Calmette–Guérin infection and rotavirus enteritis in an infant with ...
Jianlin Cai, Shuping Li, Jingyi Xu, Zhen Li, Fang Wang, Liqing Yang, Bin Jia, Yunhua Bai, Li Li   +8 more
doaj   +2 more sources

Case Report: Convalescent Plasma Achieves SARS-CoV-2 Viral Clearance in a Patient With Persistently High Viral Replication Over 8 Weeks Due to Severe Combined Immunodeficiency (SCID) and Graft Failure. [PDF]

Front Immunol, 2021
Keitel V, Bode JG, Feldt T, Walker A, Müller L, Kunstein A, Klindt C, Killer A, Senff T, Timm J, Ostermann P, Damagnez M, Lübke N, Adams O, Schaal H, Antoch G, Neubert J, Albrecht P, Meuth S, Elben S, Mohring A, Fischer JC, Bölke E, Hoenig M, Schulz AS, Luedde T, Jensen B.   +26 more
europepmc   +3 more sources

Glucose stimulates human beta cell replication in vivo in islets transplanted into NOD–severe combined immunodeficiency (SCID) mice [PDF]

Diabetologia, 2010
Helena Levitt, Travis J. Cyphert, Jordan L. Pascoe, Douglas A. Hollern, Noella Abraham, R. J. Lundell, Teresa Gonzalez‐de la Rosa, LC Romano, Bin Zou, Christopher P. O’Donnell, Andrew F. Stewart, Adolfo Garcı́a-Ocaña, Laura Alonso   +12 more
openalex   +2 more sources

Evaluation of newborn screening for severe combined immunodeficiency (SCID). [PDF]

Br J Gen Pract, 2021
Important features about a screening programme for newborn infants are that it should accurately, without too many false positives, detect a disease that is serious, where effective management is readily available and early presymptomatic detection and intervention should reduce morbidity and mortality.
Nightingale R, Cavanagh C, Gennery AR.
europepmc   +5 more sources

Severe combined immunodeficiency with BCG-osis by salvage therapy with allogeneic hematopoietic stem cell transplantation: cases report and literature review [PDF]

BMC Pediatrics
Background Severe combined immunodeficiency(SCID) combined with Bacillus Calmette-Guérin(BCG) disease(BCG-osis) is a rare but life-threatening complication in pediatric patients who received allogeneic hematopoietic stem cell transplantation (allo-HSCT).
Yuqing Jiao, Quan Li, Zhi Chen, Li Yang, Zhuo Wang, Fang Tao, Yu Du, Xiuwen Xu, Zuofeng Li, Hao Xiong   +9 more
doaj   +2 more sources

Atypical Hemolytic Uremic Syndrome (aHUS) and Adenosine Deaminase (ADA)-Deficient Severe Combined Immunodeficiency (SCID)-Two Diseases That Exacerbate Each Other: Case Report. [PDF]

Int J Mol Sci, 2021
Bogdał A, Badeński A, Pac M, Wójcicka A, Badeńska M, Didyk A, Trembecka-Dubel E, Dąbrowska-Leonik N, Walaszczyk M, Matysiak N, Morawiec-Knysak A, Szczepański T, Szczepańska M.   +12 more
europepmc   +3 more sources