Results 131 to 140 of about 1,917,601 (292)

Severe eosinophilic asthma in Chinese C‐BIOPRED asthma cohort [PDF]

Clinical and Translational Medicine, 2022
Qingling Zhang, Xiuhua Fu, Changzheng Wang, Huahao Shen, Lei Zhu, Guochao Shi, Zhongmin Qiu, Zhongguang Wen, Wei Gu, Wei Luo, Lina Zhao, Yunqin Chen, Sam Lim, Chang Xiao, Jian Kang, Yunhui Zhang, Mao Huang, Jinfu Xu, Kewu Huang, Qiang Li, Xiangyan Zhang, Jianping Zhao, Xiaoxia Liu, Shenghua Sun, Huaping Tang, Bei He, Shaoxi Cai, Ping Chen, Chunhua Wei, Guangfa Wang, Ping Chen, Lixin Xie, Jiangtao Lin, Yuling Tang, Zhihai Han, Kian Fan Chung, Nanshan Zhong, the C‐BIOPRED consortium   +37 more
openaire   +3 more sources

Treatment Persistence and Factors Associated With Discontinuation in Real‐World Biologic Therapy for Chronic Rhinosinusitis With Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Biologic therapies are effective for severe, uncontrolled CRSwNP, yet real‐world data on treatment persistence remain limited. Methods This retrospective single‐center study included 95 adults with CRSwNP who initiated dupilumab (88.4%), mepolizumab, or omalizumab between 2021 and 2025.
Hen Chaushu, Yuval Presman, Roni Vass, Narin Nard Carmel‐Neiderman, Liyona Kampel, Forsan Jahashan, Nidal Muhanna, Eiman Abu Bandora, Avraham Abergel   +8 more
wiley   +1 more source

Exploring novel perspectives on eosinophilic inflammation in severe asthma

Two recent articles by the same research group documented that patients with severe eosinophilic asthma exhibit an increased proportion of a subtype of eosinophils, namely CD62Llow inflammatory eosinophils (iEos) and identified an intriguing correlation ...
Motta A., D'Anna S. E., Maniscalco M., Ambrosino P., Candia C.   +4 more
core   +1 more source

Where Eastern Medicine Meets Western Medicine: A World Review of the Management of Chronic Cough

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Purpose To summarize current Western and Eastern approaches to the evaluation and management of chronic cough, with particular emphasis on etiology‐directed therapy, cough hypersensitivity, behavioral interventions, neuromodulators, procedural treatments, and traditional remedies.
Thomas Zheng Jie Teng, Zhi Xuan Koh, Justin Yi Shen Lim, Kavimalar Ravi, Jin Wayne Kyler Ong, Christina Hui Lee Ng   +5 more
wiley   +1 more source

Eosinophilic Sialodochitis: A Rare Comorbidity of Severe Asthma

Journal of Investigational Allergy and Clinical Immunology, 2023
O, González, C, Picado, E, Arismendi, I, Alobid, J, Ramirez, A, Valero, I, Bobolea   +6 more
openaire   +2 more sources

The experiences, perceptions and needs of people living with food chemical intolerances and dietitians: A qualitative study

Nutrition &Dietetics, EarlyView.
Abstract Aim This study explored the experiences, perceptions and needs of people living with food chemical intolerances and dietitians involved in their dietary management in Australia. Methods Semi‐structured online interviews were conducted with people living with food chemical intolerance and dietitians. Key themes were derived by consensus between
Annabel K. Clancy, Sarah Pfeiffer, Patricia Maddigan, Anne‐Therese McMahon   +3 more
wiley   +1 more source

Novel Bispecific Engagers Targeting the CεmX Domain of mIgE‐Expressing Cells

Allergy, EarlyView.
We developed bispecific TCE & NKCE targeting the CεmX domain of mIgE to eliminate IgE‐producing cells. Both constructs demonstrated potent, specific, dose‐dependent cytotoxicity and selective immune activation in vitro. These results highlight their promise as off‐the‐shelf, potentially curative therapeutics for IgE‐associated allergic diseases ...
Constantin Möller, Julia Hambach, Alessa Zoe Schaffrath, Thomas Eden, Sophia Cichutek, Anna Josephine Gebhardt, Natalie Tode, Ronald Maitschke‐Rajasekharan, Philipp Lewe, Sharon Qi, Susanne Witt, Marie Eggers, Nicola M. Tomas, Friedrich Haag, Friedrich Koch‐Nolte, Boris Fehse, Kristoffer Riecken   +16 more
wiley   +1 more source

Exhaled Volatile Organic Compounds Identify Allergic Patients Among Individuals With Chronic Rhinitis

Allergy, EarlyView.
Exhaled decane and nonadecane discriminate allergic (AR + LAR) from non‐allergic (NAR + HC) subjects among individuals with chronic rhinitis. LAR patients display higher levels of exhaled nonadecane than NAR individuals at baseline. Subjects with FeNO≥ 25 ppb have higher levels of exhaled decane, nonanal, and styrene than individuals with FeNO < 25 ppb
Rosa Alba Sola‐Martinez, Laura Zubiaga‐Fernandez, Marta Figuerola, Anyith Cruz‐Amaya, Carlos J. Aranda, Maria J. Torres, Ibon Eguiluz‐Gracia, Carmen Rondon, Teresa De Diego Puente, Almudena Testera‐Montes   +9 more
wiley   +1 more source

The effects of anti-sense interleukin-5 gene transferred by recombinant adeno-associated virus in allergic rats [PDF]

, 2008
The accumulation and infiltration of eosinophils in airways is one of the most important characteristics of asthma, and is mediated partly by secretion of IL-5 from Th2 lymphocytes.
Weining Xiong, Qingfeng Song, Yongjian Xu, Xiansheng Liu, Daxiong Zeng, Yong Cao, Chao Cao   +6 more
core  

Preventive Application of House Dust Mite‐Sublingual Immunotherapy Induces Blocking Antibodies in Sensitized Preschool Children

Allergy, EarlyView.
HDM‐pSLIT induced IgG, IgG1, and IgG4 specific to major HDM allergens in sensitized non‐allergic preschool children without increasing HDM‐sIgE. It blunted the development of new sensitizations and reduced HDM reactivity in skin and basophils. HDM‐pSLIT treated children displayed a blocking effect on HDM‐induced basophil activation.
Varsha Dwivedi, Klara Schmidthaler, Hilal Demir, Justyna Sieber, René Gaupmann, Livia Mia Gona‐Höpler, Christina Bannert, Saskia Gruber, Eleonora Dehlink, Thomas Eiwegger, Alexandra Graf, Barbara Bohle, Zsolt Szépfalusi   +12 more
wiley   +1 more source