Results 141 to 150 of about 93,898 (384)

Severe Asthma—Perspectives From Adult and Pediatric Pulmonology

Frontiers in Pediatrics, 2019
Both adults and children with severe asthma represent a small proportion of the asthma population; however, they consume disproportionate resources. For both groups it is important to confirm the diagnosis of severe asthma and ensure that modifiable ...
Louise Fleming, Liam Heaney
doaj   +1 more source

Cytokine and Lipid Mediator Regulation of Group 2 Innate Lymphoid Cells (ILC2s) in Human Allergic Airway Disease. [PDF]

, 2017
The recent discovery of group 2 innate lymphoid cells (ILC2s) has caused a paradigm shift in the understanding of allergic airway disease pathogenesis.
Cavagnero, Kellen, Doherty, Taylor A
core   +2 more sources

Effect of the Arg16Gly β₂‐Adrenergic Receptor Polymorphism on Long‐Term Mepolizumab Response and Clinical Remission in Severe Eosinophilic Asthma: A Genotype‐Stratified, Multicenter Study

Allergy, EarlyView.
This study examines the association between the rs1042713 (Arg16Gly) polymorphism of the β2‐adrenergic receptor and the risk of severe eosinophilic asthma, as well as its influence on mepolizumab long‐term effectiveness and clinical remission. The Arg16 allele is associated with increased risk of severe disease and potentially diminished long‐term ...
Santi Nolasco, Evelina Fagone, Raffaele Campisi, Andrea Portacci, Giulia Scioscia, Corrado Pelaia, Angelantonio Maglio, Claudio Candia, Vitaliano Nicola Quaranta, Isabella Carrieri, Alessandro Saglia, Alessandro Vatrella, Girolamo Pelaia, Carlo Vancheri, Maria Pia Foschino Barbaro, Maria D'Amato, Giovanna Elisiana Carpagnano, Nunzio Crimi, Claudia Crimi, the Southern Italy Network on Severe Asthma Therapy   +19 more
openalex   +2 more sources

Beyond eosinophils: A proteomic dissection of remodeling and inflammation in suspected eosinophilic esophagitis

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Eosinophilic esophagitis (EoE) is characterized by eosinophilic inflammation and epithelial remodeling. However, current biomarkers focus predominantly on eosinophilia, overlooking basal cell hyperplasia (BCH), a histologic feature that may persist despite treatment.
Adi Eindor‐Abarbanel, Nimrod Moss‐ Ophir, Netanel Agajany, Daniel L. Cohen, Vered Richter, Haim Shirin, Efrat Broide, Tzippora Shalem   +7 more
wiley   +1 more source

Nasal histamine responses in nonallergic rhinitis with eosinophilic syndrome [PDF]

, 2015
Background: Nonallergic rhinitis with eosinophilic syndrome (NARES) is persistent, without atopy, but with ≥25% nasal eosinophilia. Hypereosinophilia seems to contribute to nasal mucosa dysfunction.
Ciofalo, Andrea, de Vincentiis, Marco, Fusconi, Massimo, Greco, Antonio, Magliulo, Giuseppe, Romeo, Raffaello, Soldo, Pietro, Zambetti, Giampietro   +7 more
core   +1 more source

MEPOLIZUMAB IN SEVERE EOSINOPHILIC ASTHMA [PDF]

Chest, 2020
Q. Shahzad, M. Zaheer
openaire   +1 more source

Lower Plasma Antioxidant Defense and Heat Shock Proteins Mark Intra‐Amniotic Sludge Ultrasound Finding

Journal of Ultrasound in Medicine, EarlyView.
Objectives Intra‐amniotic sludge is an independent risk factor for preterm birth. It consists of a biophysical sonographic finding in the amniotic fluid, formed by dense echogenic particles near the cervical internal orifice, due to sterile or infectious inflammatory processes.
Clarissa Chavez Ortiz Roberto, Lílian Corrêa Costa‐Beber, Lucas Machado Sulzbacher, Jaíne Borges dos Santos, Anna Karolina Kretschmann Florencio de Souza Bagetti, Eduardo Becker Jr, Matias Nunes Frizzo, Thiago Gomes Heck, Mirna Stela Ludwig   +8 more
wiley   +1 more source

Level of Eosinophil Cationic Protein in Sputum of Chemical Warfare Victims [PDF]

Objective(s) Considering fair response to inhaled corticosteroids and reports of severe air way hyper responsiveness in chemical warfare victims (CWV), a role for eosinophilic inflammation (i.e. asthma) was postulated.
توحیدی, محمد, جعفريان, امير حسين, خاكزاد, محمد رضا, خواجه دلوئی, محمد, عطاران, داود, قبادی مراللو, حسن, محمدزاده لاری, شهرزاد, مير صدرائی, مجيد   +7 more
core  

TGFβ1 single-nucleotide polymorphism C-509T alters mucosal cell function in pediatric eosinophilic esophagitis. [PDF]

, 2020
Eosinophilic esophagitis (EoE) is a chronic Th2 antigen-driven disorder associated with tissue remodeling. Inflammation and remodeling lead to esophageal rigidity, strictures, and dysphagia. TGFβ1 drives esophageal remodeling including epithelial barrier
Aceves, SS, Barrett, K, Bezryadina, A, Dohil, R, Duong, LD, Kurten, R, Liu, Z, Manresa, MC, Newbury, RO, Rawson, R   +9 more
core  

Eosinophil Apoptosis and Clearance in Asthma [PDF]

, 2013
Peer reviewedPublisher ...
Bickham U.R., Duval E., Fadok V.A., Fadok V.A., Gaipl U.S., Hart S.P., Luttmann W., Meagher L.C., Schwartz B.R., Walsh G.M.   +9 more
core   +3 more sources